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c-Fms-IN-8

c-Fms-IN-8 structure

CAS No.: 1255303-58-2

Chemical Name:: c-Fms-IN-8

Synonyms: cFmsIN8,c Fms IN 8;Methanone, [3-[4-[(4-ethylphenyl)methoxy]-3-methoxyphenyl]-1-azetidinyl][4-(2-hydroxyethoxy)-2-pyridinyl]-

CBNumber:: CB48054339

Molecular Formula:: C27H30N2O5

Molecular Weight:: 462.54

MDL Number:: MFCD32067931

MOL File:: 1255303-58-2.mol

Last updated:2024-07-02 08:55:09

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c-Fms-IN-8 Properties

Boiling point	671.2±55.0 °C(Predicted)
Density	1.230±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
pka	13.89±0.10(Predicted)
form	Solid
color	White to off-white

c-Fms-IN-8 Chemical Properties,Uses,Production

Description

c-Fms-IN-8 (compound 4a) is a colony stimulating factor-1 receptor (CSF-1R, c-FMS) Type II inhibitor, with an IC50 of 9.1 nM[1]. IC50: 9.1 nM (CSF-1R)[1].

References

[1]. Ikegashira K, et al. Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models. Bioorg Med Chem Lett. 2019 Jan 1;29(1):115-118.

c-Fms-IN-8 Preparation Products And Raw materials

Raw materials

Preparation Products

c-Fms-IN-8 Suppliers

Global( 5)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7892	56
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	021-59167510 18117107507	vip@med-life.cn	China	5014	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Sichuan Wei Keqi Biological Technology Co., Ltd.	56
TargetMol Chemicals Inc.	58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd	58

cFmsIN8,c Fms IN 8 Methanone, [3-[4-[(4-ethylphenyl)methoxy]-3-methoxyphenyl]-1-azetidinyl][4-(2-hydroxyethoxy)-2-pyridinyl]- 1255303-58-2