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FAK inhibitor 2

CAS No.
2354405-14-2
Chemical Name:
FAK inhibitor 2
Synonyms
FAK inhibitor 2;1-Piperazinecarbodithioic acid, 4-[4-[[4-[[2-[(methylamino)carbonyl]phenyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]benzoyl]-, 2-(dimethylamino)ethyl ester
CBNumber:
CB48054399
Molecular Formula:
C29H33F3N8O2S2
Molecular Weight:
646.75
MDL Number:
MFCD32067961
MOL File:
2354405-14-2.mol
Last updated:2024-07-02 08:55:09

FAK inhibitor 2 Properties

Density 1.382±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 14.57±0.46(Predicted)
form Solid
color White to off-white

FAK inhibitor 2 Chemical Properties,Uses,Production

Description

FAK inhibitor 2 is a potent focal adhesion kinase (FAK) inhibitor with an IC50 ?of 0.07?nM, with antitumor and anti-angiogenesis activities[1]. IC50: 0.07?nM (FAK)[1]

References

[1]. Su Y, et al. Discovery of 2,4-diarylaminopyrimidine derivatives bearing dithiocarbamate moiety as novel FAK inhibitors with antitumor and anti-angiogenesis activities. Eur J Med Chem. 2019 May 18;177:32-46.

FAK inhibitor 2 Preparation Products And Raw materials

Raw materials

Preparation Products

FAK inhibitor 2 Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10000 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 23963 58
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 hanfangpharma@126.com China 30968 58
FAK inhibitor 2 1-Piperazinecarbodithioic acid, 4-[4-[[4-[[2-[(methylamino)carbonyl]phenyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]benzoyl]-, 2-(dimethylamino)ethyl ester 2354405-14-2