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Macropa-NCS

Macropa-NCS structure

CAS No.: 2146095-31-8

Chemical Name:: Macropa-NCS

Synonyms: Macropa-NCS;Macropa NCS,MacropaNCS;6-((16-((6-carboxypyridin-2-yl)methyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecan-7-yl)methyl)-4-isothiocyanatopicolinic acid;2-Pyridinecarboxylic acid, 6-[[16-[(6-carboxy-2-pyridinyl)methyl]-1,4,10,13-tetraoxa-7,16-diazacyclooctadec-7-yl]methyl]-4-isothiocyanato-

CBNumber:: CB48054450

Molecular Formula:: C27H35N5O8S

Molecular Weight:: 589.66

MDL Number:: MFCD31813825

MOL File:: 2146095-31-8.mol

Last updated:2023-05-21 10:59:17

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Macropa-NCS Properties

Boiling point	802.7±65.0 °C(Predicted)
Density	1.33±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble in DMSO
pka	2.94±0.10(Predicted)

Macropa-NCS Chemical Properties,Uses,Production

Description

Macropa-NCS is conjugated to trastuzumab as well as to the prostate-specific membrane antigen-targeting compound RPS-070. A promising therapeutic radionuclide applied in the treatment of soft-tissue metastases[1].

References

[1]. Thiele NA, et al. An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14712-14717.

Macropa-NCS Preparation Products And Raw materials

Raw materials

Preparation Products

Macropa-NCS Suppliers

Global( 5)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Xi'an Confluore Biological Technology Co., Ltd.	+86-156-80926068 +86-15680926068	1924344760@qq.com	China	4824	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd	0431-80514535 19917294565	caoy@chemextension.com	China	4758	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	21667	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 18112977050	cb5@aikonchem.com	China	10529	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Xi'an Confluore Biological Technology Co., Ltd.	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd	58
TargetMol Chemicals Inc.	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	58

Macropa-NCS Macropa NCS,MacropaNCS 2-Pyridinecarboxylic acid, 6-[[16-[(6-carboxy-2-pyridinyl)methyl]-1,4,10,13-tetraoxa-7,16-diazacyclooctadec-7-yl]methyl]-4-isothiocyanato- 6-((16-((6-carboxypyridin-2-yl)methyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecan-7-yl)methyl)-4-isothiocyanatopicolinic acid 2146095-31-8