ChemicalBook >> CAS DataBase List >>E3 ligase Ligand-Linker Conjugates 36

E3 ligase Ligand-Linker Conjugates 36

CAS No.
1351169-40-8
Chemical Name:
E3 ligase Ligand-Linker Conjugates 36
Synonyms
cIAP1 Ligand-Linker Conjugates 14;E3 ligase Ligand-Linker Conjugates 36;12,15,18-Trioxa-2,6,9-triazaeicosanedioic acid, 4-hydroxy-7-(2-methylpropyl)-5,8-dioxo-3-(phenylmethyl)-, 1-(9H-fluoren-9-ylmethyl) ester, (3R,4S,7S)-
CBNumber:
CB48054713
Molecular Formula:
C39H49N3O10
Molecular Weight:
719.82
MDL Number:
MFCD32197266
MOL File:
1351169-40-8.mol
Last updated:2025-04-18 09:52:21

E3 ligase Ligand-Linker Conjugates 36 Properties

Boiling point 981.3±65.0 °C(Predicted)
Density 1.239±0.06 g/cm3(Predicted)
pka 3.39±0.10(Predicted)

E3 ligase Ligand-Linker Conjugates 36 Chemical Properties,Uses,Production

Uses

cIAP1 Ligand-Linker Conjugates 14 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 14 can be used to design SNIPERs[1].

IC 50

cIAP1

References

[1] Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78. DOI:10.1016/j.bmc.2011.09.041

E3 ligase Ligand-Linker Conjugates 36 Preparation Products And Raw materials

Raw materials

Preparation Products

E3 ligase Ligand-Linker Conjugates 36 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1592 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18478 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 13417589054 trendseenbio@gmail.com China 9070 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 176345344 7 17634854698 1959525201@qq.com China 8068 58
Adooq Bioscience LLC 400-025-6535 sales@adooq.cn China 18215 58
cIAP1 Ligand-Linker Conjugates 14 E3 ligase Ligand-Linker Conjugates 36 12,15,18-Trioxa-2,6,9-triazaeicosanedioic acid, 4-hydroxy-7-(2-methylpropyl)-5,8-dioxo-3-(phenylmethyl)-, 1-(9H-fluoren-9-ylmethyl) ester, (3R,4S,7S)- 1351169-40-8