5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester

CAS No.
1847464-89-4
Chemical Name:
5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
Synonyms
Mobocertinib succinate intermediate;5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
CBNumber:
CB49018527
Molecular Formula:
C29H35N7O5
Molecular Weight:
561.64
MDL Number:
MOL File:
1847464-89-4.mol
Last updated:2024-03-07 09:33:46

5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Properties

Boiling point 754.3±70.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
pka 9.00±0.28(Predicted)

5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Chemical Properties,Uses,Production

Description

The IUPAC Name of 5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester is isopropyl 2-((4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxy-5-nitrophenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate. This compound is an intermediate of Mobocertinib succinate which is an orally active and irreversible EGFR/HER2 inhibitor.

5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Suppliers

Global( 1)Suppliers
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Enki Biopharmaceuticals (Shanghai) Limited
+86-0086-2157680326 +8613916707528 yusu@enkibiopharma.com China 46 58
5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-nitrophenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester Mobocertinib succinate intermediate 1847464-89-4