ChemicalBook >> CAS DataBase List >>ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
- CAS No.
- 51931-66-9
- Chemical Name:
- ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
- Synonyms
- Dea no. 9750;trans-Tilidine;Tilidate [ban];Einecs 257-522-9;ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate;Ethyl trans-2-(dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylate;3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethyl ester, trans-;3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethyl ester, (1R,2S)-rel-
- CBNumber:
- CB4928566
- Molecular Formula:
- C17H23NO2
- Molecular Weight:
- 273.37
- MDL Number:
- MOL File:
- 51931-66-9.mol
Last updated:2023-05-04 17:34:39
| Boiling point | 96 °C(Press: 0.01 Torr) |
|---|---|
| Density | 1.06±0.1 g/cm3(Predicted) |
| pka | 8.26±0.40(Predicted) |
| EWG's Food Scores | 1 |
| FDA UNII | GY33N31E9Y |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H332-H302-H373-H312-H334 |
| Precautionary statements | P260-P314-P501-P280-P302+P352-P312-P322-P363-P501-P261-P285-P304+P341-P342+P311-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312 |
ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate Chemical Properties,Uses,Production
Uses
Tilidine is an opioid used primarily as a painkiller it inhibits the enzyme adenylyl cyclase.
Definition
ChEBI: Dextilidine is an ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate that has S configuration at the carbon bearing the phenyl group and R configuration at the carbon bearing the dimethylamino group. The opioid analgesic tilidine is the racemate comprising equimolar amounts of dextilidine and its enantiomer, ent-dextilidine. A prodrug, tilidine is converted by the liver to the active analgesic, nortilidine; virtually all of the opioid activity resides in the (1S,2R) isomer (i.e. the isomer derived from dextilidine). It has a role as an opioid analgesic and a prodrug. It is an enantiomer of an ent-dextilidine.
ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Tilidate [ban]
Ethyl trans-2-(dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylate
trans-Tilidine
ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethyl ester, (1R,2S)-rel-
3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethyl ester, trans-
Dea no. 9750
Einecs 257-522-9
51931-66-9