2H-Pyran-2-one, 6-(2,4-dihydroxy-6-methylphenyl)-4-methoxy-
- CAS No.
- 59163-53-0
- Chemical Name:
- 2H-Pyran-2-one, 6-(2,4-dihydroxy-6-methylphenyl)-4-methoxy-
- Synonyms
- Aloenin aglycone;2H-Pyran-2-one, 6-(2,4-dihydroxy-6-methylphenyl)-4-methoxy-
- CBNumber:
- CB49753350
- Molecular Formula:
- C13H12O5
- Molecular Weight:
- 248.23
- MDL Number:
- MOL File:
- 59163-53-0.mol
2H-Pyran-2-one, 6-(2,4-dihydroxy-6-methylphenyl)-4-methoxy- Chemical Properties,Uses,Production
Uses
Aloenin aglycone (compound 13) is an NF-κB inhibitor that can be isolated from aloe exudate. Aloenin aglycone inhibits TNFα-induced NF-κB transcriptional activity (IC50: 18.7 μM). Aloenin aglycone (10 μM) also reduced inducible nitric oxide synthase (iNOS) and intercellular adhesion molecule 1 (ICAM-1) gene expression after treatment of HepG2 cells with 10 ng/mL TNFα[1].
References
[1] Sun Y N, et al. Isolation and identification of chromone and pyrone constituents from Aloe and their anti-inflammatory activities[J]. Journal of Functional Foods, 2016, 21: 232-239.
[2] Sun Y N. et al. Isolation and identification of chromone and pyrone constituents from Aloe and their anti-inflammatory activities[J]. Journal of Functional Foods, 2016, 21: 232-239.
2H-Pyran-2-one, 6-(2,4-dihydroxy-6-methylphenyl)-4-methoxy- Preparation Products And Raw materials
Raw materials
Preparation Products
2H-Pyran-2-one, 6-(2,4-dihydroxy-6-methylphenyl)-4-methoxy- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu DeSiTe Biological Technology Co., Ltd | 17308096051 | 3001048290@qq.com | China | 6219 | 58 |
| Supplier | Advantage |
|---|---|
| Chengdu DeSiTe Biological Technology Co., Ltd | 58 |