D-erythro-Sphingosine (1,2-13 1,1-D2)
- CAS No.
- 2692623-81-5
- Chemical Name:
- D-erythro-Sphingosine (1,2-13 1,1-D2)
- Synonyms
- CBNumber:
- CB510570279
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
D-erythro-Sphingosine (1,2-13 1,1-D2) Chemical Properties,Uses,Production
Description
Sphingosine-13C2-d2 (d18:1) is intended for use as an analytical standard for the quantification of sphingosine (d18:1) by GC- or LC-MS. Sphingosine (d18:1) is formed primarily from the breakdown of ceramide.1 Sphingosine (d18:1) inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.1 Phosphorylation of sphingosine (d18:1) by sphingosine kinases 1 and 2 (SPHK1, SPHK2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.2,3,4
References
1. Hannun, Y.A., Luberto, C., and Argraves, K.M. Enzymes of sphingolipid metabolism: From modular to integrative signaling Biochemistry 40(16),4893-4903(2001).
2. Takuwa, Y., Takuwa, N., and Sugimoto, N. The Edg family G protein-
3. Ishii, I., Fukushima, N., Ye, X., et al. Lysophospholipid receptors: Signaling and biology Annu. Rev. Biochem. 73,321-354(2004).
4. Kluk, M.J., and Hla, T. Signaling of sphingosine-
D-erythro-Sphingosine (1,2-13 1,1-D2) Preparation Products And Raw materials
Raw materials
Preparation Products
D-erythro-Sphingosine (1,2-13 1,1-D2) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1977 | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11975 | 58 |
Supplier | Advantage |
---|---|
Yichang Zhongyitai Trading Co., Ltd. | 58 |
Shanghai Yifei Biotechnology Co. , Ltd. | 58 |