1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]-
- CAS No.
- 1529814-60-5
- Chemical Name:
- 1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]-
- Synonyms
- PS121912;PS-121912;PS 121912;1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]-
- CBNumber:
- CB510673507
- Molecular Formula:
- C24H21F3N2O
- Molecular Weight:
- 410.44
- MDL Number:
- MOL File:
- 1529814-60-5.mol
1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]- Chemical Properties,Uses,Production
Description
PS121912 is a potent and selective VDR-coactivator inhibitor.
Uses
PS121912 is a selective vitamin D receptor (VDR)-coregulator inhibitor. PS121912 has acceptable metabolic stability in vivo. PS121912 can be used for the research of cancer[1].
in vivo
PS121912 shows an acceptable metabolic stability and can inhibit the metabolic enzyme CYP3A4 at higher concentrations in vivo cancer studies[1].
References
[1] Sidhu PS, et al. Anticancer activity of VDR-coregulator inhibitor PS121912. Cancer Chemother Pharmacol. 2014;74(4):787-798. DOI:10.1007/s00280-014-2549-y
1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]- Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32202 | 58 |
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19889 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19746 | 58 |
Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 11183 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
Chengdu Peter-like Biotechnology Co., Ltd. | 58 |