ChemicalBook >> CAS DataBase List >>1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]-

1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]-

CAS No.
1529814-60-5
Chemical Name:
1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]-
Synonyms
PS121912;PS-121912;PS 121912;1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]-
CBNumber:
CB510673507
Molecular Formula:
C24H21F3N2O
Molecular Weight:
410.44
MDL Number:
MOL File:
1529814-60-5.mol
Last updated:2025-04-18 09:52:22

1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]- Properties

Boiling point 542.6±50.0 °C(Predicted)
Density 1.283±0.06 g/cm3(Predicted)
form Solid
pka 17.60±0.30(Predicted)
color Off-white to light yellow

1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]- Chemical Properties,Uses,Production

Description

PS121912 is a potent and selective VDR-coactivator inhibitor.

Uses

PS121912 is a selective vitamin D receptor (VDR)-coregulator inhibitor. PS121912 has acceptable metabolic stability in vivo. PS121912 can be used for the research of cancer[1].

in vivo

PS121912 shows an acceptable metabolic stability and can inhibit the metabolic enzyme CYP3A4 at higher concentrations in vivo cancer studies[1].

References

[1] Sidhu PS, et al. Anticancer activity of VDR-coregulator inhibitor PS121912. Cancer Chemother Pharmacol. 2014;74(4):787-798. DOI:10.1007/s00280-014-2549-y

1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32202 58
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19889 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19746 58
Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200 13308200041 2851167782@qq.com China 11183 58

View Lastest Price from 1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PS121912 pictures 2024-10-28 PS121912
1529814-60-5
US $1520.00-2500.00 / mg 10g TargetMol Chemicals Inc.
  • PS121912 pictures
  • PS121912
    1529814-60-5
  • US $1520.00-2500.00 / mg
  • TargetMol Chemicals Inc.
1H-Indole-3-methanamine, α-(4-methoxyphenyl)-2-methyl-N-[4-(trifluoromethyl)phenyl]- PS 121912 PS121912 PS-121912 1529814-60-5