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ChemicalBook >> CAS DataBase List >>1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]-

1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]-

1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]- Structure
1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]- structure
CAS No.
2368903-18-6
Chemical Name:
1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]-
Synonyms
FHT-1015;1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]-
CBNumber:
CB510966991
Molecular Formula:
C25H25N5O4S3
Molecular Weight:
555.69
MDL Number:
MOL File:
2368903-18-6.mol
Last updated:2024-07-02 08:55:09
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1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]- Properties

Density 1.41±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble to 100 mM in DMSO
pka 7.66±0.50(Predicted)
form Solid
color White to off-white

1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]- Chemical Properties,Uses,Production

Biological Activity

FHT-1205 is a potent SMARCA4/SMARCA2 ATPase (BRG1 and BRM) inhibitor with IC50s of ≤10 nM (WO2020160180A1; compound 67)[1].

storage

Store at -20°C

References

[1]. Rishi G. Vaswani, et al. Compounds and uses thereof. WO2020160180A1.

1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]- Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai XingMo Biotechnology Co., Ltd. 13524779951 2075692521@qq.com China 310 55
NANJING TOMMLAB PHARMATECH Co.,LTD -- litianang@caremo.com.cn China 258 58
Nanjing Machido Pharmaceutical Technology Co., Ltd. 19556085883 sales@machidopharma.com China 367 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 4476 58
Supplier Advantage
Aladdin Scientific 		58
Shanghai XingMo Biotechnology Co., Ltd. 55
NANJING TOMMLAB PHARMATECH Co.,LTD 58
Nanjing Machido Pharmaceutical Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nantong QuanYi Biotechnology Co., Ltd 58
1H-Pyrrole-3-carboxamide, 1-(methylsulfonyl)-N-[(1S)-3-(methylthio)-1-[[[4-[3-(4-pyridinyl)phenyl]-2-thiazolyl]amino]carbonyl]propyl]- FHT-1015 2368903-18-6 C25H25N5O4S3