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ChemicalBook >> CAS DataBase List >>1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone

1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone

1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Structure
1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone structure
CAS No.
821794-92-7
Chemical Name:
1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone
Synonyms
FMK;Fluoromethyl Ketone;RSK2 kinase inhibitor;FMK - RSK inhibitor Fmk;Fluoromethyl Ketone-MEA, FMK-MEA;1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-fluoroethanone;1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone;Ethanone, 1-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoro-;1-[5-amino-9-(3-hydroxypropyl)-7-(4-methylphenyl)-2,4,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetraen-8-yl]-2-fluoro-ethanone
CBNumber:
CB51161837
Molecular Formula:
C18H19FN4O2
Molecular Weight:
342.37
MDL Number:
MFCD22417081
MOL File:
821794-92-7.mol
Last updated:2024-07-02 08:55:09
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1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Properties

Density 1.36
storage temp. Store at -20°C
solubility insoluble in H2O; ≥17.1 mg/mL in DMSO; ≥28.7 mg/mL in EtOH
form solid
color White to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
HS Code  2933998090
NFPA 704
0
2 0

1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 4690 Fmk ≥97%(HPLC) 821794-92-7 10 $214 2021-12-16 Buy
TRC F657735 FMK 821794-92-7 1mg $110 2021-12-16 Buy
ChemScene CS-0648 FMK 99.30% 821794-92-7 2mg $132 2021-12-16 Buy
Axon Medchem Axon1848 FMK-RSKinhibitorFmk 99% 821794-92-7 5mg $137.5 2021-12-16 Buy
ApexBio Technology A3420 FMK 821794-92-7 5mg $192 2021-12-16 Buy
Product number Packaging Price Buy
4690 10 $214 Buy
F657735 1mg $110 Buy
CS-0648 2mg $132 Buy
Axon1848 5mg $137.5 Buy
A3420 5mg $192 Buy

1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Chemical Properties,Uses,Production

Uses

FMK is a potent irreversible RSK1/2 inhibitor (IC50 = 15 nM). Inactivates the C-terminal auto-kinase domain activity. Suppresses RSK2 kinase activity in RSK2-expressing HNSCC cell lines. Reduces HNSCC cell invasive ability. Displays no effect on EGF-stimulated phosphorylation of ERK1 or ERK2.

target

RSK1

storage

Store at -20°C

1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Preparation Products And Raw materials

Raw materials

Preparation Products

1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Suppliers

Global( 67)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32760 60
Biochempartner 		0086-13720134139 candy@biochempartner.com CHINA 967 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19553 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29826 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10522 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24738 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 4692 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Biochempartner 		58
BOC Sciences 		58
career henan chemical co 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
LEAP CHEM CO., LTD. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Amadis Chemical Company Limited 		58

View Lastest Price from 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3- d]pyrimidin-6-yl]-2-fluoroethanone pictures 2020-01-02 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3- d]pyrimidin-6-yl]-2-fluoroethanone
821794-92-7
 US $1.00 / KG 1KG Min98% HPLC g/kg/ton Career Henan Chemical Co

1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Spectrum

1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone(821794-92-7)1HNMR
1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-fluoroethanone RSK2 kinase inhibitor FMK FMK - RSK inhibitor Fmk Ethanone, 1-[4-amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoro- 1-[5-amino-9-(3-hydroxypropyl)-7-(4-methylphenyl)-2,4,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetraen-8-yl]-2-fluoro-ethanone Fluoromethyl Ketone Fluoromethyl Ketone-MEA, FMK-MEA 821794-92-7 Akt mTOR PI3K API