Fentonium
- CAS No.
- 5868-06-4
- Chemical Name:
- Fentonium
- Synonyms
- Z-326;FA-402;Ulcesium;Fentonium;Phentonium;Ketoscilium;[8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate bromide;[8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenyl-propanoate bromide;3-hydroxy-2-phenyl-propionic acid [8-[2-keto-2-(4-phenylphenyl)ethyl]-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester bromide
- CBNumber:
- CB51178738
- Molecular Formula:
- C31H34BrNO4
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- 5868-06-4.mol
Melting point | 203-205° (dec); mp 193-194° |
---|---|
alpha | D23 -5.68° (c = 5 in DMF); D25 -4.7° (c = 5 in DMF) |
FDA UNII | 26BF4S8FO5 |
ATC code | A03BB04 |
SAFETY
Risk and Safety Statements
Toxicity | LD50 in mice (mg/kg): 12.1 i.v.; >400 s.c. and orally (Teotino, Della Bella) |
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Fentonium Chemical Properties,Uses,Production
Originator
Hoelcesium,Zambon,Italy
Manufacturing Process
5.50g (0.02 mol) of p-phenylphenacyl bromide were dissolved in 56 cc of
anhydrous acetone previously heated to about 40°C. This solution was added,
with stirring, to a solution of 5.70 g (0.02 mol) of 1-hyoscyamine in 43 cc of
anhydrous acetone; the reaction solution was maintained at 45°C and stirred
for about six hours.
After standing overnight in the refrigerator, the precipitate was collected by
filtration and dried in vacuo at 60°C. Yield: 10.2 g; MP = 193°C to 194°C.
Therapeutic Function
Anticholinergic, Spasmolytic
Fentonium Preparation Products And Raw materials
Fentonium Suppliers
Global( 1)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
Fentonium
FA-402
Ketoscilium
Phentonium
Ulcesium
Z-326
[8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate bromide
[8-methyl-8-[2-oxo-2-(4-phenylphenyl)ethyl]-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenyl-propanoate bromide
3-hydroxy-2-phenyl-propionic acid [8-[2-keto-2-(4-phenylphenyl)ethyl]-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester bromide
5868-06-4
C31H34BrNO4