GERANYLGERANIOL
- CAS No.
- 24034-73-9
- Chemical Name:
- GERANYLGERANIOL
- Synonyms
- (2e,6e,10e)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol;(E,E,E)-Geranylgeranyl alcohol;CJ24095;CJ 24095;CJ-24095;FT0626663;FT-0626663;Tetraprenol;Geranylgeranio;GERANYLGERANIOL
- CBNumber:
- CB5120277
- Molecular Formula:
- C20H34O
- Molecular Weight:
- 290.48
- MDL Number:
- MFCD00129083
- MOL File:
- 24034-73-9.mol
- MSDS File:
- SDS
| Boiling point | 152-153 °C(Press: 0.07 Torr) |
|---|---|
| Density | 0.8930 g/cm3(Temp: 18 °C) |
| storage temp. | -20°C |
| solubility | Chloroform (Sparingly), Dichloromethane (Slightly), Ethyl Acetate (Slightly) |
| form | liquid |
| pka | 14.42±0.10(Predicted) |
| color | Colourless to Light Yellow |
| BRN | 1913779 |
| Stability | Light Sensistive, Temperature Sensitive |
| InChIKey | OJISWRZIEWCUBN-QIRCYJPOSA-N |
| FDA UNII | AIA02AJA3A |
| UNSPSC Code | 12352202 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29052290 | |||||||||
| NFPA 704 |
|
GERANYLGERANIOL price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | G3278 | Geranylgeraniol ≥85% (GC) | 24034-73-9 | 100mg | $80.8 | 2024-03-01 | Buy |
| Cayman Chemical | 13272 | Geranylgeranyl Alcohol ≥98% | 24034-73-9 | 25mg | $28 | 2024-03-01 | Buy |
| Cayman Chemical | 13272 | Geranylgeranyl Alcohol ≥98% | 24034-73-9 | 50mg | $43 | 2024-03-01 | Buy |
| Cayman Chemical | 13272 | Geranylgeranyl Alcohol ≥98% | 24034-73-9 | 100mg | $68 | 2024-03-01 | Buy |
| TRC | G367500 | Geranylgeraniol(Natural) | 24034-73-9 | 50mg | $45 | 2021-12-16 | Buy |
GERANYLGERANIOL Chemical Properties,Uses,Production
Chemical Properties
Light Yellow Oil
Uses
A intermediate in the lipidation of proteins, which plays a great importance for a variety of biological processes such as cell signalling
Uses
Geranylgeraniol, a precursor to Geranylgeranylpyrophosphate (G367600), is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-adsorption, inhibition of osteoclast formation, and kinase activation in vitro.
Definition
ChEBI: Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.
Biochem/physiol Actions
As the pyrophosphate, the metabolic precursor of all diterpenes. Screening in vitro shows this to be a potent and selective agent against Mycobacterium tuberculosis.
in vivo
Geranylgeraniol (725 mg/kg/d; p.o.; 90 d) is not toxicologically significant with a dose below 725 mg/kg/d in rats[3].
Geranylgeraniol (483 mg/kg/d; p.o.; 10 d) suppresses lipopolysaccharide-induced inflammation via inhibition of nuclear factor-κB activation in rats[4].
| Animal Model: | Han Wistar rats (169-192 g for male; 116-152 g for female)[3] |
| Dosage: | 0, 725, 1450, and 2900 mg/kg |
| Administration: | Oral gavage; once daily; 90 days |
| Result: | Showed the lowest observed adverse effect level (LOAEL) for local effects and the no observed adverse effect level (NOAEL) for systemic effects as 725 mg/kg/d. Reduced body weights by 12.9 and 21.6% in the intermediate- and high-dose group males, respectively, compared to controls. |
| Animal Model: | Wistar rats (male, 8-week-old, 130-150 g)[4] |
| Dosage: | 0, 48.3, 483, 4830 mg/kg |
| Administration: | Oral gavage; once daily; 10 days; with or not LPS challenge (i.p.; 0.5 mg/kg) |
| Result: | Suppressed LPS-induced inflammatory cytokines and mRNA expression of LPS-induced inflammatory genes in liver with doses of 483 mg/kg and 4830 mg/kg. Suppressed protein levels of IRAK1, TRAF6, and TAK1, originating from transcriptional down-regulation with doses of 483 mg/kg and 4830 mg/kg. |
GERANYLGERANIOL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20235 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from GERANYLGERANIOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-03-03 | Geranylgeraniol
24034-73-9
|
US $0.00-0.00 / KG | 1KG | 95.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2024-11-19 | Geranylgeraniol
24034-73-9
|
US $30.00-39.00 / mg | ≥98% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-03-29 | GERANYLGERANIOL
24034-73-9
|
US $8.00-0.90 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- Geranylgeraniol
24034-73-9
- US $0.00-0.00 / KG
- 95.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- Geranylgeraniol
24034-73-9
- US $30.00-39.00 / mg
- ≥98%
- TargetMol Chemicals Inc.
-
- GERANYLGERANIOL
24034-73-9
- US $8.00-0.90 / KG
- 99%
- Henan Fengda Chemical Co., Ltd