ChemicalBook >> CAS DataBase List >>Cyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, 3-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-5,5a,6,6a-tetrahydro-, (5aS,6R,6aR)-

Cyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, 3-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-5,5a,6,6a-tetrahydro-, (5aS,6R,6aR)-

CAS No.
1544739-76-5
Chemical Name:
Cyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, 3-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-5,5a,6,6a-tetrahydro-, (5aS,6R,6aR)-
Synonyms
MK-8666;Cyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, 3-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-5,5a,6,6a-tetrahydro-, (5aS,6R,6aR)-
CBNumber:
CB512247126
Molecular Formula:
C29H31NO6S
Molecular Weight:
521.62
MDL Number:
MOL File:
1544739-76-5.mol
Last updated:2023-03-31 09:12:59

Cyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, 3-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-5,5a,6,6a-tetrahydro-, (5aS,6R,6aR)- Properties

Boiling point 741.8±60.0 °C(Predicted)
Density 1.304±0.06 g/cm3(Predicted)
pka 3.94±0.20(Predicted)

Cyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, 3-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-5,5a,6,6a-tetrahydro-, (5aS,6R,6aR)- Chemical Properties,Uses,Production

Description

MK-8666 is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pancreatic beta cells and in intestinal enteroendocrine cells. Thus, MK-8666 has been investigated for treatment of type 2 diabetes mellitus and has been shown to robustly lower glucose without negative effects.

Cyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, 3-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-5,5a,6,6a-tetrahydro-, (5aS,6R,6aR)- Preparation Products And Raw materials

Raw materials

Preparation Products

Cyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, 3-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-5,5a,6,6a-tetrahydro-, (5aS,6R,6aR)- Suppliers

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TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28091 58
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TargetMol Chemicals Inc. 58
Cyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, 3-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-5,5a,6,6a-tetrahydro-, (5aS,6R,6aR)- MK-8666 1544739-76-5