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(2-(2-(2-((2-bromoacetyl)amino)ethoxy)ethoxy)ethoxy)acetic acid

CAS No.
173323-22-3
Chemical Name:
(2-(2-(2-((2-bromoacetyl)amino)ethoxy)ethoxy)ethoxy)acetic acid
Synonyms
Bromoacetamide-PEG3-C1-acid;(2-(2-(2-((2-bromoacetyl)amino)ethoxy)ethoxy)ethoxy)acetic acid;Acetic acid, 2-[2-[2-[2-[(2-bromoacetyl)amino]ethoxy]ethoxy]ethoxy]-
CBNumber:
CB51347947
Molecular Formula:
C10H18BrNO6
Molecular Weight:
328.16
MDL Number:
MOL File:
173323-22-3.mol
Last updated:2023-02-23 14:24:01

(2-(2-(2-((2-bromoacetyl)amino)ethoxy)ethoxy)ethoxy)acetic acid Properties

Boiling point 539.5±50.0 °C(Predicted)
Density 1.449±0.06 g/cm3(Predicted)
pka 3.39±0.10(Predicted)

(2-(2-(2-((2-bromoacetyl)amino)ethoxy)ethoxy)ethoxy)acetic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation HCH0001115 14-BROMO-13-OXO-3,6,9-TRIOXA-12-AZATETRADECAN-1-OIC ACID 95.00% 173323-22-3 5MG $501.78 2021-12-16 Buy
Product number Packaging Price Buy
HCH0001115 5MG $501.78 Buy

(2-(2-(2-((2-bromoacetyl)amino)ethoxy)ethoxy)ethoxy)acetic acid Chemical Properties,Uses,Production

Biological Activity

Bromoacetamide-PEG3-C1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

(2-(2-(2-((2-bromoacetyl)amino)ethoxy)ethoxy)ethoxy)acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(2-(2-(2-((2-bromoacetyl)amino)ethoxy)ethoxy)ethoxy)acetic acid Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 29778 58
Shanghai Zhiyun Biotechnology Co., Ltd 13119135307 3809801531@qq.com China 2694 58
(2-(2-(2-((2-bromoacetyl)amino)ethoxy)ethoxy)ethoxy)acetic acid Acetic acid, 2-[2-[2-[2-[(2-bromoacetyl)amino]ethoxy]ethoxy]ethoxy]- Bromoacetamide-PEG3-C1-acid 173323-22-3