ChemicalBook >> CAS DataBase List >>SPOP-i-6lc
SPOP-i-6lc
- CAS No.
- 2136270-56-7
- Chemical Name:
- SPOP-i-6lc
- Synonyms
- SPOP-IN-1;SPOP-i-6lc;SPOP-IN-6lc;2-Imino-10-methyl-N-(2-(4-methylpiperazin-1-yl)ethyl)-5-oxo-1-(2-(thiophen-2-yl)ethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
- CBNumber:
- CB513745995
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Last updated:2025-04-18 09:52:24
SPOP-i-6lc Chemical Properties,Uses,Production
Uses
SPOP-IN-1 is a selective SPOP E3 ubiquitin ligase inhibitor. SPOP-IN-1 leads to the accumulation of tumor suppressors PTEN and DUSP7 and decreased levels of phosphorylated AKT and ERK in clear-cell renal cell carcinoma[1].
References
[1] Dong Z, et al. Structure-Activity Relationship of SPOP Inhibitors against Kidney Cancer. J Med Chem. 2020 May 14;63(9):4849-4866. DOI:10.1021/acs.jmedchem.0c00161
SPOP-i-6lc Preparation Products And Raw materials
Raw materials
Preparation Products
SPOP-i-6lc Suppliers
Global( 12)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4601 | 55 | |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 6345 | 55 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 62072 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5237 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| Hubei wei shi reagent group ltd., company | 027-59101766 13125137661 | 2853877621@qq.com | China | 7979 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19727 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd | 025-58851090 17714375163 | 2881759498@qq.com | China | 13012 | 58 |
| R&D Systems, Inc | 18003437475 18003437475 | rdname@qq.com | China | 35960 | 58 |
| Sangon Biotech (Shanghai) Co.,Ltd. | 400-821-026 | Sales@sangon.com | China | 47255 | 58 |
SPOP-i-6lc
SPOP-IN-1
SPOP-IN-6lc
2-Imino-10-methyl-N-(2-(4-methylpiperazin-1-yl)ethyl)-5-oxo-1-(2-(thiophen-2-yl)ethyl)-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide
2136270-56-7