Surinabant
- CAS No.
- 288104-79-0
- Chemical Name:
- Surinabant
- Synonyms
- SR147778;SR 147778;SR-147778;Surinabant;5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide, 5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-1-piperidinyl-;1-(2,4-Dichlorophenyl)-5-(4-bromophenyl)-4-ethyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
- CBNumber:
- CB51458052
- Molecular Formula:
- C23H23BrCl2N4O
- Molecular Weight:
- 522.26
- MDL Number:
- MFCD09970803
- MOL File:
- 288104-79-0.mol
- MSDS File:
- SDS
| Density | 1.50 |
|---|---|
| pka | 11.30±0.20(Predicted) |
| FDA UNII | SF8R9VCB0X |
Surinabant Chemical Properties,Uses,Production
Uses
Surinabant (SR 147778) is an orally active, selective cannabinoid receptor type 1 CB1R antagonist. Surinabant is used in studies of obesity and alcoholism[1][2].
Definition
ChEBI: 5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-3-pyrazolecarboxamide is a member of pyrazoles and a ring assembly.
References
[1] Klumpers LE, et al. Surinabant, a selective cannabinoid receptor type 1 antagonist, inhibits Δ9-tetrahydrocannabinol-induced central nervous system and heart rate effects in humans. Br J Clin Pharmacol. 2013 Jul;76(1):65-77. DOI:10.1111/bcp.12071
[2] Fischler PV, et al. Off-label and investigational drugs in the treatment of alcohol use disorder: A critical review. Front Pharmacol. 2022 Oct 3;13:927703. DOI:10.3389/fphar.2022.927703
Surinabant Preparation Products And Raw materials
Raw materials
Preparation Products
Surinabant Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 |
| Supplier | Advantage |
|---|---|
| CONIER CHEM AND PHARMA LIMITED | 58 |
| TargetMol Chemicals Inc. | 58 |