ChemicalBook >> CAS DataBase List >>Ufiprazole
Ufiprazole
- CAS No.
- 73590-85-9
- Chemical Name:
- Ufiprazole
- Synonyms
- e SuL;H 168/22;ufiprazole;Pyrmetazol;PyrMetazole;Omeprazolesulfide;OMEPRAZOLE SULPHIDE;Omeprazole EP Imp C;Omeprazole Impurity C;EsoMeprazol iMpurity C
- CBNumber:
- CB5146932
- Molecular Formula:
- C17H19N3O2S
- Molecular Weight:
- 329.42
- MDL Number:
- MFCD00869021
- MOL File:
- 73590-85-9.mol
Last updated:2024-08-21 22:41:43
Melting point | 122.0 to 126.0 °C |
---|---|
Boiling point | 539.7±60.0 °C(Predicted) |
Density | 1.28±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 9.81±0.10(Predicted) |
color | White to Off-White |
λmax | 307nm(MeOH)(lit.) |
InChI | InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20) |
InChIKey | XURCIPRUUASYLR-UHFFFAOYSA-N |
SMILES | C1(SCC2=NC=C(C)C(OC)=C2C)NC2=CC(OC)=CC=C2N=1 |
CAS DataBase Reference | 73590-85-9(CAS DataBase Reference) |
FDA UNII | 6FFV1V867C |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26 |
WGK Germany | 3 |
HS Code | 29339900 |
Ufiprazole price More Price(24)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | O0437 | Omeprazole Sulfide >98.0%(HPLC)(T) | 73590-85-9 | 200mg | $186 | 2024-03-01 | Buy |
TCI Chemical | O0437 | Omeprazole Sulfide >98.0%(HPLC)(T) | 73590-85-9 | 1g | $466 | 2024-03-01 | Buy |
Cayman Chemical | 18885 | Omeprazole sulfide ≥98% | 73590-85-9 | 100mg | $62 | 2024-03-01 | Buy |
Cayman Chemical | 18885 | Omeprazole sulfide ≥98% | 73590-85-9 | 1g | $448 | 2024-03-01 | Buy |
Cayman Chemical | 18885 | Omeprazole sulfide ≥98% | 73590-85-9 | 250mg | $142 | 2024-03-01 | Buy |
Ufiprazole Chemical Properties,Uses,Production
Synthesis
Ufiprazole can be synthesized by the condensation reaction of 2-mercapto-5-methoxybenzimidazole and 2-chloromethyl-4-methoxy-3,5-lutidine.
Description
Omeprazole sulfide is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole and esomeprazole . As a degradation product, it is reported to be a direct-acting inhibitor of cytochrome P450 2C19 in pooled human liver microsomes (IC50 = 9.7 μM).
Uses
Omeprazole Sulfide (Esomeprazol EP Impurity C(Omeprazole EP Impurity C)) is a metabolite of Omeprazole.
Definition
ChEBI: Omeprazole sulfide is a member of benzimidazoles.
Biological Activity
Ufiprazole (Omeprazole sulfide) is an intermediate in the production of gastric proton pump inhibitors omeprazole and esomeprazole.
![37052-78-1](/CAS/GIF/37052-78-1.gif)
![86604-75-3](/CAS/GIF/86604-75-3.gif)
![73590-85-9](/CAS/GIF/73590-85-9.gif)
Synthesis of Ufiprazole from 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE and 2-Chloromethyl-4-methoxy-3,5-dimethylpyridine hydrochloride
Ufiprazole Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 520)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9991 | 58 |
Shenzhen Excellent Biomedical Technology Co.,Ltd. | +86-0755-26050679 +86-15915472436 | sale@ex-biotech.cn | China | 1031 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | peter@yan-xi.com | China | 5873 | 58 |
Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5828 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
View Lastest Price from Ufiprazole manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-08-22 | Esomeprazole Impurity C
73590-85-9
|
US $0.00-0.00 / mg | 10mg | 0.98 | 10g | ShenZhen H&D Pharmaceutical Technology Co., LTD | |
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2024-08-20 | Omeprazole Sulfide
73590-85-9
|
US $50.00-20.00 / KG | 1KG | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD | |
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2024-08-15 | Ufiprazole
73590-85-9
|
US $40.00-40.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- Esomeprazole Impurity C
73590-85-9
- US $0.00-0.00 / mg
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-
- Omeprazole Sulfide
73590-85-9
- US $50.00-20.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
-
- Ufiprazole
73590-85-9
- US $40.00-40.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
73590-85-9(Ufiprazole)Related Search:
3,5-Dimethyl-4-methoxy-2-pyridinemethanol
Omeprazole
OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS)
Esomeprazole Impurity 3
(S)-4-Desmethoxy-4-chloro Omeprazole
4-Hydroxy Omeprazole
Omeprazole EP Impurity F
Omeprazole Sulfone N-Oxide
EsoMeprazole related substance H431/41
2-Pyridinemethanol, 4-hydroxy-3,5-dimethyl- (9CI)
1of4
5-Methoxy-2-[[(4-Methxoy-3,5-diMethylpyridin-2-yl)Methyl]sulfanyl]-1H-benziMidazole(ufiprazole)
2-[(3,5-Dimethyl-4-methoxy-2-pyridyl)methylthio]-5-methoxy-1H-benzimidazole
2-[[(3,5-Dimethyl-4-methoxy-2-pyridyl)methyl]thio]-5-methoxy-1H-benzimidazole
5-Methoxy-2-[(3,5-dimethyl-4-methoxy-2-pyridyl)methylthio]-1H-benzimidazole
5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL) THIO]-1H-BENZIMIDAZOLE ((OMEPRAZOLE SULPHIDE COMPOUND)
6-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylthio]-1H-benzimidazole
6-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfanyl]-1H-benzimidazole
6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfanyl]-1H-benzimidazole
1H-BenziMidazole, 6-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-
EsoMeprazol iMpurity C
OMeprazole IMpurity-C(EP)
6-Methoxy-2-((4-Methoxy-3,5-diMethylpyridin-2-yl)Methylthio)-1H-benzo[d]iMidazole
IMp. C (EP): 5-Methoxy-2-[[(4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl]- sulphanyl]-1H-benziMidazole (Ufiprazole)
EsoMeprazole EP IMpurity C
EsoMeprazole IMp.C ep.
5-Methoxy-2-(4-Methoxy-3,5-diMethyl-pyridin-2-ylMethylsulfanyl)-1H-benzoiMidazole
5-Methoxy-2-[[(4-Methxoy-3,5-diMethylpyridin-2-yl)Methyl]sulfanyl]-1H-benziMidazole
5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL THIO-1H-BENZIMIDAZOLE
5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYLMERCAPTOBENZIMIDAZOLE
5-METHOXY-2-[[(3,5-DIMETHYL-4-METHOXY PYRIDINYL)-METHYL]THIO]-1H-BENZIMIDAZOLE
2-[(4-METHOXYETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLTHIO]-5-METHOXYBENZIMIDAZOLE
2-{[(3,5-dimethyl-4-methoxy-2-pyridinyl)-methyl]-thio}-5-methoxy-1h-benzimidazole
OMEPRAZOLE SULPHIDE
H 168/22
ufiprazole
5-METHOXY-2-(4-METHOXYL-3,5-DIMETHYL-PYRIDINE-2-YLMETHYLSULFENYL)- 1H- BENZIMIDA
Omeprazolesulfide
5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYLTHIO-1H-BENZIMIDAZOLE(UFIPRAZOLE)
2-{[(3,5-Dimethyl-4-methoxy-2-pyridinyl)-methyl]-thio}-5-methoxy-1H benzimi
5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL THIO-1H-BENZIMIDAZOLE =98%
(1R,2S,5R)-menthyl-5(s)-cytosin-1-yl-1,3-oxathiolane-2R-carboxylate(CME)
5-METHOXY-2-{[(3,5-DIMETHYL-4-METHOXY-2-PYRIDINYL)METHYL]THIO}-1H-BENZIMIDAZOLE (OMEPRAZOLE SULFIDE)
(1R,2S,5R)-MENTHYL-5(S)-CYTOSINE-1-YL-[1,3]-OXATHIOLANE-2R-CARBOXYLATE
( IR, 2S, 5R)-menthyl C5(s)-cytosin C1-yl-[1,3] Coxathiolane-2R-carboxylate (CME)
5-METHOXY-2-(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL THIO-1H-BENZIMIDAZOLE(INTERMEDIATE OF OMEPRAZOLE)
5-Methoxy-2-((4-Methoxy-3,5-diMethylpyridin-2-yl)Methylthio)-1H-benziMidazol
EsoMeprazo interMediate B
Omeprazole Sulfur ether
Esomeprazole Magnesium Trihydrate Imp. C (EP): 5-Methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-sulphanyl]-1H-benzimidazole (Ufiprazole)
Omeprazole impurity C (PhEur)
Pyrmetazol
Omeprazole metabolite Omeprazole sulfide
Omeprazole Sulfide (Ufiprazole)
5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulphanyl)-1H-benzimidazole
Esomeprazole impurity C
Omeprazole Impurity C
5-METHOXY-2-[[(3,5-DIMETHYL-4-METHOXY PYRIDINYL)-METHYL]THIO]-1H BENZIMIDAZOLE(OMEPRAZOLE SULPHIDE)
2-[[(3,5-DiMethyl-4-Methoxy-2-pyridyl)Methyl]thio]-5-MethoxybenziMidazole
6-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]thio]-1H-benziMidazole
PyrMetazole
Ufiprazole, OMeprazole Sulphide
EsoMeprazole related substance C
5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole
Esomeprazole EP Impurity C(Omeprazole EP Impurity C)
2-[ [(4-methoxy-3,5-dimethylpyridine-2-yl)methyl]thio]-5-methoxy-1H-benzimidazole
Omeprazole Sulfide
Esomeprazole EP Impurity C / (Omeprazole Sodium EP Impurity C)
2-[(4-methoxy--3,5-dimethyl-2-pyridinyl-)-methyl-thio]-5-methoxy--benz-imidazole
e SuL