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5-METHYLCYTOSINE

5-METHYLCYTOSINE structure

CAS No.: 554-01-8

Chemical Name:: 5-METHYLCYTOSINE

Synonyms: 4-Amino-5-methylpyrimidin-2(1H)-one;5-methylcytosin;5-METHYLCYTOSINE;Cytosine, 5-methyl-;5-Methylcytosine,>96%;5-Methylcytosine (~90%);5-Methylcytosine, 97%, 97%;5-METHYLCYTOSINE USP/EP/BP;4-Amino-5-methyl-2-pyrimidinol;5-Methylcytosine, 10 mM in DMSO

CBNumber:: CB5154906

Molecular Formula:: C5H7N3O

Molecular Weight:: 125.13

MDL Number:: MFCD00233537

MOL File:: 554-01-8.mol

MSDS File:: SDS

Last updated:2024-11-19 23:02:33

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5-METHYLCYTOSINE Properties

Melting point	270°C (rough estimate)
Boiling point	232.57°C (rough estimate)
Density	1.2602 (rough estimate)
refractive index	1.6510 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Methanol (Sparingly, Heated)
pka	9.05±0.10(Predicted)
form	Crystalline
color	White to Off-White
Water Solubility	Soluble in water.
Merck	14,6050
CAS DataBase Reference	554-01-8(CAS DataBase Reference)
FDA UNII	6R795CQT4H

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319-H317

Precautionary statements

P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P280-P305+P351+P338-P337+P313P

RTECS

UW7362350

NFPA 704

	1
0		0

5-METHYLCYTOSINE price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Alfa Aesar	043492	5-Methylcytosine, 97%	554-01-8	100mg	$104	2024-03-01	Buy
Alfa Aesar	043492	5-Methylcytosine, 97%	554-01-8	500mg	$342.65	2024-03-01	Buy
TRC	M294873	5-Methylcytosine(~90%)	554-01-8	1g	$50	2021-12-16	Buy
Usbiological	C9111	Cytosine, 5-Methyl	554-01-8	50ug	$369	2021-12-16	Buy
ChemScene	CS-W008091	5-Methylcytosine 99.82%	554-01-8	100g	$372	2021-12-16	Buy

Product number	Packaging	Price	Buy
043492	100mg	$104	Buy
043492	500mg	$342.65	Buy
M294873	1g	$50	Buy
C9111	50ug	$369	Buy
CS-W008091	100g	$372	Buy

5-METHYLCYTOSINE Chemical Properties,Uses,Production

Chemical Properties

Crystals in prisms from water.

Uses

5-Methylcytosine is used as a marker to protect DNA from being cut by native methylation-sensitive restriction enzymes. It is also employed in the production of 4-amino-5-hydroxy-5-methyl-2-oxo-2,5-dihydro-imidazole-1-carbaldehyde.

Definition

ChEBI: A pyrimidine that is a derivative of cytosine, having a methyl group at the 5-position.

Purification Methods

Crystallise it from water (solubility is 3.4%). The hydrochloride has m 299-301o (sintering at 280o) (from aqueous HCl/Me2CO). [Hitchings et al. J Biol Chem 177 537 1949, Cohn J Am Chem Soc 73 1539 1951, Beilstein 25 II 183, 25 III/IV 3727.]

5-METHYLCYTOSINE synthesis

Synthesis of 5-METHYLCYTOSINE from Thymine

5-METHYLCYTOSINE Preparation Products And Raw materials

Raw materials

5-METHYL-2-THIOCYTOSINE 5-methyl-4-(1,2,4-triazol-1-yl)-pyrimidin-2-(1H)-one 2-(Ethylthio)-5-methyl-4-pyrimidinamine 2(1H)-Pyrimidinone, 4-methoxy-5-methyl- (8CI,9CI) 4-chloro-2-ethylsulfanyl-5-methyl-pyrimidine

5-Methyl-2'-deoxycytidine 5-HydroxyMethyl cytidine 5-(Hydroxymethyl)-2'-deoxycytidine 5-HYDROXYMETHYLCYTOSINE (5-methyl)dithiouracil

5-formyl-2'-deoxycytidine 5-Methylcytidine Ethanol Thymine

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Preparation Products

1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

5-METHYLCYTOSINE Suppliers

Global( 241)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chongqing Zhihe Biopharmaceutical Co., Ltd.	+86-18580541567; +8618580541567	sales@zhswyy.com	China	191	58
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29871	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49476	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	11915	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58

Supplier	Advantage
Chongqing Zhihe Biopharmaceutical Co., Ltd.	58
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Antai Fine Chemical Technology Co.,Limited	58
Zhengzhou Alfa Chemical Co.,Ltd	58
TargetMol Chemicals Inc.	58

View Lastest Price from 5-METHYLCYTOSINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-02-16	5-METHYLCYTOSINE 554-01-8	US $0.00-0.00 / kg	0.10000000149011612kg	99	20tons	Chongqing Zhihe Biopharmaceutical Co., Ltd.
2024-11-19	5-Methylcytosine 554-01-8	US $29.00 / mL		99.17%	10g	TargetMol Chemicals Inc.
2021-07-13	5-methylcytosine 554-01-8	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

5-METHYLCYTOSINE
554-01-8
US $0.00-0.00 / kg
99
Chongqing Zhihe Biopharmaceutical Co., Ltd.

5-Methylcytosine
554-01-8
US $29.00 / mL
99.17%
TargetMol Chemicals Inc.

5-methylcytosine
554-01-8
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

5-METHYLCYTOSINE Spectrum

5-METHYLCYTOSINE(554-01-8)¹HNMR

554-01-8(5-METHYLCYTOSINE)Related Search:

5'-O-(4,4'-DIMETHOXYTRITYL)-5-METHYL-N4-BENZOYL-2'-DEOXYCYTIDINE-3'-(2-CYANOETHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE 5-(TRIFLUOROMETHYL)-2'-DEOXYCYTIDINE 5-CARBOXYCYTOSINE 5-METHYLCYTOSINE 1-(2-Deoxy-beta-D-ribofuranosyl)-5-methylcytosine

2'-C-Methylcytidine 2-O-Methylcytosine 5-METHYLCYTOSINE HCL,5-METHYLCYTOSINE HYDROCHLORIDE 98%,5-METHYLCYTOSINE HYDROCHLORIDE,5-Methylcytosine hydrochloride ,98% 5-HYDROXYMETHYLCYTOSINE N4-Methylcytosine ,98%,N4-Methylcytosine

Cytosine 5-Methylcytidine FLUORESCEIN-12-DCTP BIOTIN-11-DDCTP 5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-5-METHYL-2'-DEOXYCYTIDINE

5'-METHYL-2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE TRILITHIUM SALT N4-BENZOYL-5-METHYLDEOXYCYTIDINE 3-METHYLCYTOSINE HYDROCHLORIDE

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4-Amino-5-methyl-2-pyrimidinol Cytosine, 5-methyl- 5-Methylcytosine,>96% 2(1H)-Pyrimidinone, 4-amino-5-methyl- (9CI) 4-amino-5-methyl-3H-pyrimidin-2-one 2(1H)-Pyrimidinone, 6-amino-5-methyl- 2(1H)-Oxo-4(3H)-imino-5-methylpyrimidine 2(1H)-Oxo-4-amino-5-methylpyrimidine 2-Hydroxy-4-amino-5-methylpyrimidine 4-Amino-5-methyl-1,2-dihydropyrimidine-2-one 4(6)-AMino-2-hydroxy-5-MethylpyriMidine 4-AMino-5-Methyl-2(1H)pyriMidinone 4-aMino-5-Methyl-1,2-dihydropyriMidin-2-one 5-Methylcytosine, 97%, 97% 5-METHYLCYTOSINE 5-methylcytosin 5-Methylcytosine (~90%) 5-METHYLCYTOSINE USP/EP/BP 4-Amino-5-methylpyrimidin-2(1H)-one 5-Methylcytosine, 10 mM in DMSO 554-01-8 Nucleic acids Pyrimidines PYRIMIDINE Elisa Kit-Rat Elisa Kit