Etamsylate
- CAS No.
- 2624-44-4
- Chemical Name:
- Etamsylate
- Synonyms
- ETHAMSYLATE;e141;Phenolsulfonate;md141;eselin;HeMsyl;K-Stat;Sylate;aglumin;altodor
- CBNumber:
- CB5165128
- Molecular Formula:
- C10H17NO5S
- Molecular Weight:
- 263.31
- MDL Number:
- MFCD00867499
- MOL File:
- 2624-44-4.mol
| Melting point | 125° |
|---|---|
| Density | 1.3441 (rough estimate) |
| refractive index | 1.5060 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Very soluble in water, freely soluble in methanol, soluble in anhydrous ethanol, practically insoluble in methylene chloride. |
| form | Solid |
| color | White to Pale Red |
| Merck | 14,3722 |
| Stability | Hygroscopic |
| InChI | InChI=1S/C6H6O5S.C4H11N/c7-4-1-2-5(8)6(3-4)12(9,10)11;1-3-5-4-2/h1-3,7-8H,(H,9,10,11);5H,3-4H2,1-2H3 |
| InChIKey | HBGOLJKPSFNJSD-UHFFFAOYSA-N |
| SMILES | C1(S(=O)(=O)O)=CC(=CC=C1O)O.N(CC)CC |
| CAS DataBase Reference | 2624-44-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 24YL531VOH |
| ATC code | B02BX01 |
| EPA Substance Registry System | Ethamsylate (2624-44-4) |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P313-P337+P313-P362-P403+P233-P405-P501 |
| RTECS | DB6145000 |
| HS Code | 2921.19.6190 |
| HazardClass | IRRITANT |
| Toxicity | LD50 i.v. in mice, rats: 800, 1350 mg/kg (Esteve) |
Etamsylate price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E1830000 | Etamsylate European Pharmacopoeia (EP) Reference Standard | 2624-44-4 | e1830000 | $153 | 2024-03-01 | Buy |
| TCI Chemical | E1145 | Etamsylate >98.0%(HPLC)(T) | 2624-44-4 | 1g | $30 | 2024-03-01 | Buy |
| TCI Chemical | E1145 | Etamsylate >98.0%(HPLC)(T) | 2624-44-4 | 5g | $89 | 2024-03-01 | Buy |
| TRC | E889950 | Ethamsylate | 2624-44-4 | 10mg | $55 | 2021-12-16 | Buy |
| TRC | E889950 | Ethamsylate | 2624-44-4 | 25mg | $70 | 2021-12-16 | Buy |
Etamsylate Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Hemostatic;prostaglandin synthesis inhibitor
Uses
Haemostatic / Anti Coagulant
Definition
ChEBI: Etamsylate is a sulfonic acid derivative and an organosulfur compound.
Biological Activity
Etamsylate is a haemostatic agent th at is used for the management of blood loss. Apparently etamsylate increases capillary wall resistance and platelet adhesives by inhibition of the biosynthesis of prostaglandins causing platelet disaggregation in a presence of vascular wound. Recent studies suggest th at etamsylate antagonizes anti-coagulant activity of heparin.
Mechanism of action
Etamsylate is an antihaemorrhagic and vasoprotective agent. It increases platelet adhesiveness and capillary vascular wall resistance, thereby reducing capillary exudation and blood loss.
Clinical Use
Short-term treatment of blood loss in menorrhagiaProphylaxis of surgical bleeding (unlicensed)
Side effects
Significant: Hypotension (parenteral). Rarely, severe hypersensitivity reaction, including anaphylaxis.
Blood and lymphatic system disorders: Parenteral: Rarely, neutropenia, agranulocytosis, thrombocytopenia.
Gastrointestinal disorders: Nausea, vomiting, diarrhoea, abdominal pain or discomfort.
General disorders and administration site conditions: Asthenia (parenteral). Rarely, fever.
Musculoskeletal and connective tissue disorders: Rarely, arthralgia.
Nervous system disorders: Headache.
Skin and subcutaneous tissue disorders: Rash.
Vascular disorders: Rarely, thromboembolism (parenteral).
Metabolism
Etamsylate is excreted unchanged, mainly in the urine.
Etamsylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Suikang Pharmaceutical Co.,Ltd. | +86-18239973690 +86-18239973690 | sales@suikangpharm.com | China | 311 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8804 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12829 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659 +86-13153181156 | sales@sdperfect.com | China | 294 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Wuhan Quanjinci New Material Co.,Ltd. | +86-15271838296; +8615271838296 | kyra@quanjinci.com | China | 1512 | 58 |
| airuikechemical co., ltd. | +86-18353166132 +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Apeloa production Co.,Limited | +8619933239880 | admin@apcl.com.cn | China | 861 | 58 |
View Lastest Price from Etamsylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-02-18 | etamsylate
2624-44-4
|
US $80.00 / kg | 1kg | 99 | 5000 | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2025-02-17 | Etamsylate
2624-44-4
|
US $0.00 / kg | 1kg | 99.0% | 1tons | Henan Suikang Pharmaceutical Co.,Ltd. | |
 |
2025-02-14 | Pharmaceutical Intermediates
2624-44-4
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd |
-
- etamsylate
2624-44-4
- US $80.00 / kg
- 99
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Etamsylate
2624-44-4
- US $0.00 / kg
- 99.0%
- Henan Suikang Pharmaceutical Co.,Ltd.
-
- Pharmaceutical Intermediates
2624-44-4
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd