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Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester

Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester structure

CAS No.: 69739-34-0

Chemical Name:: Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester

Synonyms: TBS-OTF;tbdms-otf;TERT-BUTYLDIMETHYLSILYL TRIFLUOROMETHANESULFONATE;TERT-BUTYLDIMETHYLSILYL TRIFLATE;TBDMS TRIFLATE;TBS Triflate;tert-butyldimethylsilyl ester;TBMDS-OTF;t-Butyldimethylsilyl triflate;T-BUTYLDIMETHYLSILYL TRIFLUOROMETHANESULFONATE

CBNumber:: CB5192348

Molecular Formula:: C7H15F3O3SSi

Molecular Weight:: 264.34

MDL Number:: MFCD00000405

MOL File:: 69739-34-0.mol

MSDS File:: SDS

Last updated:2024-12-11 16:58:07

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Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester Properties

Melting point	<0°C
Boiling point	65-67 °C12 mm Hg(lit.)
Density	1.151 g/mL at 25 °C(lit.)
refractive index	n20/D 1.385(lit.)
Flash point	98 °F
storage temp.	2-8°C
solubility	Slightly miscible with chloroform.
form	Fuming Liquid
Specific Gravity	1.151
color	Clear colorless to yellow
Water Solubility	DECOMPOSES
Sensitive	Moisture Sensitive
Hydrolytic Sensitivity	8: reacts rapidly with moisture, water, protic solvents
BRN	2370068
Stability	Moisture Sensitive
InChIKey	WLLIXJBWWFGEHT-UHFFFAOYSA-N
CAS DataBase Reference	69739-34-0(CAS DataBase Reference)
FDA UNII	EE45S257MT
NIST Chemistry Reference	Tert-butyldimethylsilyl trifluoromethanesulfonate(69739-34-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS05,GHS07

Signal word

Danger

Hazard statements

H226-H314-H335

Precautionary statements

P210-P233-P240-P280-P303+P361+P353-P305+P351+P338

Hazard Codes

C,F

Risk Statements

10-34-37

Safety Statements

26-36/37/39-45-25-16

RIDADR

UN 2920 8/PG 2

WGK Germany

10-21

Hazard Note

Flammable/Corrosive

TSCA

HazardClass

PackingGroup

III

HS Code

29310095

NFPA 704

	2
3		0

Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	226149	tert-Butyldimethylsilyl trifluoromethanesulfonate reagent grade, 98%	69739-34-0	1g	$38.8	2024-03-01	Buy
Sigma-Aldrich	226149	tert-Butyldimethylsilyl trifluoromethanesulfonate reagent grade, 98%	69739-34-0	5g	$91.8	2024-03-01	Buy
Sigma-Aldrich	8.18313	tert-Butyldimethylsilyl trifluoromethanesulfonate for synthesis	69739-34-0	25mL	$372	2024-03-01	Buy
TCI Chemical	T1525	tert-Butyldimethylsilyl Trifluoromethanesulfonate >98.0%(T)	69739-34-0	5g	$70	2024-03-01	Buy
TCI Chemical	T1525	tert-Butyldimethylsilyl Trifluoromethanesulfonate >98.0%(T)	69739-34-0	25g	$211	2024-03-01	Buy

Product number	Packaging	Price	Buy
226149	1g	$38.8	Buy
226149	5g	$91.8	Buy
8.18313	25mL	$372	Buy
T1525	5g	$70	Buy
T1525	25g	$211	Buy

Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester Chemical Properties,Uses,Production

Chemical Properties

clear colorless to yellow fuming liquid

Physical properties

bp 60°C/7 mmHg; colorless oil, d 1.151 g cm?3. Solubility: sol most organic solvents such as pentane, CH2Cl2, etc.

Uses

tert-Butyldimethylsilyl trifluoromethanesulfonate is involved in the introduction of a bulky tert-butyl dimethylsilyl group onto a cis-bis(alkenyl)oxirane used in Cope rearrangement. It is associated with a thiolane and promotes the chalcogenide-Morita-Baylis-Hillman reaction. Further, it is used as a highly reactive silylating agent. In addition to this, it is used to prepare enol silyl ethers by reacting with ketones and lactones.

Uses

t-Butyldimethylsilyl Trifluoromethanesulfonate is used as a highly reactive silylating agent and Lewis acid capable of converting primary, secondary, and tertiary alcohols1b to the corresponding TBDMS ethers, and converting ketones and lactones, into their enol silyl ethers; promoting conjugate addition of alkynylzinc compounds and triphenylphosphine5 to α,β-enones; activation of chromones in [4 + 2] cycloaddition reactions;rearrangement of allylic tributylstannyl silyl ethers; activation of pyridine rings toward Grignard reagents and transalkylation of tertiary amine N-oxides;and transformation of N-t-butoxycarbonyl groups into N-alkoxycarbonyl groups.

Uses

TrifluoroMethanesulfonic acid tert-butyldiMethylsilyl ester is a highly reactive silylating agent and lewis acid capable of converting primary, secondary and tertiary alcohols to their respectctive TBDMS. TrifluoroMethanesulfonic acid tert-butyldiMethylsilyl ester is also used to covert ketones and lactones into their enol silyl ethers.

Preparation

to 24 g (0.16 mol) of t-butyldimethylchlorosilane at 23°C under argon is added 14 mL (0.16 mol) of trifluoromethanesulfonic acid dropwise. The solution is heated at 60°C for 10 h, at which time no further hydrogen chloride evolves (removed through a bubbler). The resulting product is distilled under reduced pressure: 34 g (80% yield) of TBDMS triflate; bp 60°C/7 mmHg.

Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester Preparation Products And Raw materials

Raw materials

Heptane tert-Butyldimethylsilyl chloride Trifluoromethanesulfonic acid

Preparation Products

trans-3,4-Difluorocinnamic acid TERT-BUTYLDIMETHYLSILANOL (3-BROMOPROPOXY)-TERT-BUTYLDIMETHYLSILANE 6-(4-{2-[3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-ethylidene}-7a-methyl-octahydro-inden-1-yl)-2-methyl-heptan-2-ol 40-O-[2-(t-butyldimethylsilyl)oxy]ethyl rapamycin

(4-BROMOPHENOXY)-TERT-BUTYLDIMETHYLSILANE Silane, (1,1-dimethylethyl)dimethyl[(1-methylene-2-propenyl)oxy]- ((1-(4-bromophenyl)hexyl)oxy)(tert-butyl)dimethylsilane(WXC06094) R-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy] diphenylMethyl]-Pyrrolidine

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Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester Suppliers

Global( 435)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531153977	allison@yan-xi.com	China	5857	58
Hebei Weibang Biotechnology Co., Ltd	+8617732866630	bess@weibangbio.com	China	18151	58
airuikechemical co., ltd.	+86-18353166132 +86-18353166132	sales02@airuikechemical.com	China	983	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883 +86-16264648883	niki@zlchemi.com	China	3001	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29793	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18750	58
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
Fluoropharm Co., Ltd.	+86-0571-85586753; +8613336034509	sales@fluoropharm.com	China	1376	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32956	60

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Weibang Biotechnology Co., Ltd	58
airuikechemical co., ltd.	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Shanghai Time Chemicals CO., Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Fluoropharm Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60

View Lastest Price from Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-01-03	Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester 69739-34-0	US $10.00 / kg	1kg	99%	20 ton	Hebei Zhuanglai Chemical Trading Co Ltd
2024-12-24	Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester 69739-34-0	US $0.00-0.00 / Kg	1Kg	99.99%	20 tons	airuikechemical co., ltd.
2024-10-31	Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester 69739-34-0	US $30.00-10.00 / KG	50KG	99%	500000kg	Hebei Weibang Biotechnology Co., Ltd

Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester
69739-34-0
US $10.00 / kg
99%
Hebei Zhuanglai Chemical Trading Co Ltd

Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester
69739-34-0
US $0.00-0.00 / Kg
99.99%
airuikechemical co., ltd.

Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester
69739-34-0
US $30.00-10.00 / KG
99%
Hebei Weibang Biotechnology Co., Ltd

Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester Spectrum

Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester(69739-34-0)¹HNMR Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester(69739-34-0)Raman Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester(69739-34-0)FT-IR

69739-34-0(Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester)Related Search:

Trifluoromethanesulfonic acid TERT-BUTYL VINYL ETHER Butylated hydroxyanisole tert-Butyldimethylsilyl chloride tert-Butylchlorodiphenylsilane

TERT-BUTYLDIMETHYL(2-PROPYNYLOXY)SILANE Trifluoromethanesulfonic anhydride Trifluoroacetic anhydride TERT-BUTYL PROPIOLATE Trifluoromethanesulfonic acid difluoromethyl ester

TERT-BUTYLMETHOXYPHENYLSILYL BROMIDE 2-Methyl-N-(thiophen-2-ylMethyl)propan-2-aMine tert-Butyldiphenylsilane tert-Butyl(3-fluorophenoxy)dimethylsilane Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester

ETHYLDIMETHYLSILANE T-BUTYLDIMETHYLSILANE Trifluoromethane

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Methanesulfonic acid, trifluoro-, (1,1-dimethylethyl)dimethylsilyl ester t-butyldimethylsilyltrifluormethansulfonate t-Butylmethylsilyl triflate TBDMS triflate, Trifluoromethanesulfonic acid tert-butyldimethylsilylester SILANE TBM2 TRIFLATE Silane TBM2 triflate, TBDMS triflate, Trifluoromethanesulfonic acid tert-butyldimethylsilylester (R)-4-isopropyl-5,5-diphenyloxazolidine-2-thione Methanesulfonic acid, trifluoro-, (1,1-diMethylethyl)diMethylsilyl ester (9CI) tert-ButyldiMethylsilyl trifluoroMethanesulfonate reagent grade, 98% Methanesulfonic acid, 1,1,1-trifluoro-, (1,1-dimethylethyl)dimethylsilyl ester tert-Butyldimethyl(trifluoromethylsulfonyloxy)silane tert-Butyldimethylsilyl trifluoromethanesulfonate,98% BUTYLDIMETHYLSILYLTRIFLUOROMETHANESULFONATE tert-Butyldimethylsilyl trifluoromethanesulphonateTBDMS triflate tert-Butyldimethylsilyl trifluoromethanesulphonate 97+% tert-ButyldiMethylsilyl trifluoroMethanesulfonate, 98% 5ML (1,1-DiMethylethyl)diMethylsilyl TrifluoroMethanesulfonate tert-ButyldiM TrifluoroMethanesulfonic Acid (1,1-DiMethylethyl)diMethylsilyl ester tert-Butyldimethylsilyl Triflate TBDMS Triflate Trifluoromethanesulfonic Acid tert-Butyldimethylsilyl Ester T-BUTYLDIMETHYLSILYLTRIFLUOROMETHANE-SULPHONATE TERT-BUTYLDIMETHYLSILYL TRIFLUOROMETHANESULPHONATE TRIFLUOROMETHANESULFONIC ACID TERT-BUTYLDIMETHYLSILYL ESTER tert-BUTYLDIMETHYLSILYL TRIFLUOROMETHANESULFONATE 98% tert-Butyldimethylsilyl trifluoromethane tert-Butyldimethylsilyl trifluoromethanesulphonate 98% tert-Butyldimethylsilyltrifluoromethanesulphonate98% tert-Buthyldimethylsilyl trifluoromethane sulfonate TRIFLUOROMETHANESULFONIC ACID*T-BUTYLDIM ETHYLSILYL t-Butyldimethylsilyltrifluoromethanesulfonate,98% ert-Butyldimethylsilyl Trifluoromethanesulfonate tert-Butyldimethylsilyl trifluoromethanesulfonate 1,1,1-trifluoro-Methanesulfonic acid (1,1-dimethylethyl)dimethylsilyl ester tert-Butyldimethylsilyl trifluoromethanesulfonate, for synthesis Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester ISO 9001：2015 REACH tert-Butyldimethylsilyl Trifluoromethanesulfonate (TBDMS triflate) extrapure, 98% t-Butyldimethylsilyl triflate T-BUTYLDIMETHYLSILYL TRIFLUOROMETHANESULFONATE TBDMS TRIFLATE TBMDS-OTF TBS-OTF TERT-BUTYLDIMETHYLSILYL TRIFLATE TERT-BUTYLDIMETHYLSILYL TRIFLUOROMETHANESULFONATE tbdms-otf tert-butyldimethylsilyl ester TBS Triflate (1,1-Dimethylethyl)dimethylsilyl 1,1,1-trifluoromethanesulfonate TERT-BUTYLDIMETHYLSILYL TRIFLUROMETHANESULFONATE(TBDMS-TRIFLATE) ter-Butyldimethylsilyltrifluoromethane sulfonate Tert-butyldimethylsilyl Trifluoromethanesulfonate (Rosuvastatin Intermediate) tert-butyldimethylsilyl trifluromethanesulfonate Everolimus Impurity 40 DKFELEX0082 DKSI129 69739-34-0 69739-37-0 C7H15F3O3SSi CH33SiCH32OSO2CF3