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Propyphenazone

CAS No.
479-92-5
Chemical Name:
Propyphenazone
Synonyms
Budirol;Causyth;Larodon;Cibalgina;Isopyrine;Isopropchin;Isopropyrine;Propyphenazon;PROPYPHENAZONE;(-)-Asparagine
CBNumber:
CB5193729
Molecular Formula:
C14H18N2O
Molecular Weight:
230.31
MDL Number:
MFCD00053368
MOL File:
479-92-5.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

Propyphenazone Properties

Melting point 102-105°C
Boiling point 372.3°C (rough estimate)
Density 1.0371 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methylene chloride.
pka 1.46±0.65(Predicted)
form Solid
color White to Off-White
Water Solubility 743.6g/L(25.35 ºC)
Merck 14,7871
BRN 204533
Stability Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 479-92-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII OED8FV75PY
ATC code N02BB04
NIST Chemistry Reference Propyphenazone(479-92-5)
EPA Substance Registry System 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl- (479-92-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn
Risk Statements  36/37/38-22
Safety Statements  26-36/37/39
WGK Germany  3
RTECS  CD2800000
HS Code  2933.39.9200
NFPA 704
0
2 0

Propyphenazone price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1389 Propyphenazone Pharmaceutical Secondary Standard; Certified Reference Material 479-92-5 1g $97.5 2024-03-01 Buy
TCI Chemical I0656 4-Isopropylantipyrine >98.0%(GC) 479-92-5 25g $64 2024-03-01 Buy
Sigma-Aldrich P3750000 Propyphenazone European Pharmacopoeia (EP) Reference Standard 479-92-5 p3750000 $153 2024-03-01 Buy
TRC P838380 Propyphenazone 479-92-5 50g $875 2021-12-16 Buy
American Custom Chemicals Corporation API0007224 PROPYPHENAZONE 95.00% 479-92-5 25G $950 2021-12-16 Buy
Product number Packaging Price Buy
PHR1389 1g $97.5 Buy
I0656 25g $64 Buy
P3750000 p3750000 $153 Buy
P838380 50g $875 Buy
API0007224 25G $950 Buy

Propyphenazone Chemical Properties,Uses,Production

Description

This uncharacterized alkaloid has been described by Hartsen as occurring in Iso_x0002_pyrum thalictroides L. No chemical or physical characteristics are known.

Chemical Properties

solid

Uses

Analgesic; antipyretic; anti-inflammatory.

Definition

ChEBI: A pyrazolone derivative that is antipyrine substituted at C-4 by an isopropyl group.

brand name

539 grippe-dragees;Amipylo-n;Balpiren;Baukal;Caffalgina;Camoplex;Cantacin;Cerebrol;Daturmed;Degripol;Dentocaps a;Dim-antos;Dolibral;Dolo-mineuron;Dysmalgin;Ejcopyrin;Epizon;Escomen;Estesina;Fd 8;Febral;Finigripp;Grippocaps;Heaven;Infantex;Influvit;Isopronazon;Kavapyret;Kuronde;Lysadestat;Mamaslu;Milneuron;Myo-europan;Neuramin;Neuridal;Neuro-spondryl;Nodiras;Noric;Otobacid;Pfeil;Reomin;Retamex;Rheumanol;Rhinivict;Sanalgin-p;Saridon neu;Saridone;Sedospin;Servalgin;Sonotryl;Spalt;Spongamed;Stona;Synpyrin;Vivcet;Wauco-sin;Wecontrin.

World Health Organization (WHO)

Propyphenazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1951 for the treatment of rheumatic disorders. As it is structurally related to aminophenazone it has been associated with severe blood dyscrasias. However, it cannot be transformed into potentially carcinogenic nitrosamines and has therefore been widely used as a replacement drug for aminophenazone. In certain countries, products containing propyphenazone have now been restricted in their indications, whereas in others they are still available, sometimes as over-the-counter preparations. See also WHO comment for aminophenazone.

Clinical Use

Propyphenazone is a derivative of phenazone and has a similar analgesic and antipyretic action. It is used as a monocompound as well as in multi-ingredient preparations.

References

Hartsen., J. Chem. Soc., 511 (1873) Mirande., Compt. rend., 168,316 (1919)

Propyphenazone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 238)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5892 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Casorganics US Corp
+17326109938 sales@casorganics.com CHINA 174 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845 sales@amoychem.com China 6383 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from Propyphenazone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Propyphenazone pictures 2024-11-29 Propyphenazone
479-92-5
US $0.00 / Kg/Drum 1KG 98%min 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
Propyphenazone pictures 2024-11-19 Propyphenazone
479-92-5
US $40.00 / g 99.81% 10g TargetMol Chemicals Inc.
Propyphenazone pictures 2024-10-11 Propyphenazone
479-92-5
US $1.90 / KG 1KG 99% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
  • Propyphenazone pictures
  • Propyphenazone
    479-92-5
  • US $0.00 / Kg/Drum
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Propyphenazone pictures
  • Propyphenazone
    479-92-5
  • US $1.90 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co,.LTD
2,3-dimethyl-4-isopropyl-1-phenyl-3-pyrazolin-5-on 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl- 3H-Pyrazol-3-one,1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl- 3-Pyrazolin-5-one, 2,3-dimethyl-4-isopropyl-1-phenyl- 4-ISOPROPYL-2,3-DIMETHYL-1-PHENYL-5-PYRAZOLONE 2,3-Dimethyl-1-phenyl-4-isopropylpyrazolone 4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazoline-5-on 4-ISO-PROPYL-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLIN-5-ONE(PROPYPHENAZONE) 3,3-Dimethyl-2-Methylene Norcamphone 1,5-Dimethyl-4-(1-methylethyl)-2-phenyl-1,2-dihydro-3H-pyrazol-3-one 1,5-dimethyl-2-phenyl-4-propan-2-yl-pyrazol-3-one 1,5-dimethyl-2-phenyl-4-propan-2-ylpyrazol-3-one 4-isopropyl-1,5-dimethyl-2-phenyl-pyrazol-3-one PROPYLPHENAZONE ANTIBIOTICTPJ-B Propyphenazone (EDMF) 1,2-Dihydro-4-isopropyl-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3h-pyrazol-3-on 3-Pyrazolin-5-one, 4-isopropyl-2,3-dimethyl-1-phenyl- 4-Isopropyl-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one 4-isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on 4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one 4-Isopropyl-2,3-dimethyl-5-oxo-1-phenyl-3-pyrazoline 4-isopropyl-antipyrin 4-Isopropylphenazone Antipyrine, 4-isopropyl- Budirol Causyth Cibalgina Isopropchin Isopropylantipyrin Isopropyrine Isopyrine Larodon ISOPROPYLANTIPYRINE ISOPROPYLANTIPYRINUM 4-ISOPROPYLANTIPYRINE 4-ISOPROPYL-1,5-DIMETHYL-2-PHENYL-3-PYRAZOLONE PROPYPHENAZONE ISOPROPYLPHENAZONE 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-Pyrazol-3-one 1,2-dihydro-1,5-dimethyl-4-(isopropyl)-2-phenyl-pyrazol-3-one 1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-one 1-phenyl-2,3-dimethyl-4-isopropyl-5-Pyrazolone 1-Phenyl-2,3-dimethyl-4-isopropylpyrazol-5-one 2,3-Dimethyl-4-isopropyl-1-phenyl-3H-pyrazolin-5-one Phentermine Solution, 100ppm 2-propyl-2H-phenazin-1-one Propyphenazone (4-Isopropylantipyrine) 4-Isopropylantipyrine> Propyphenazone CRS 4-isopropyl-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one Propyphenazone USP/EP/BP Propyphenazone, Pharma Isopropyl PhenazoneQ: What is Isopropyl Phenazone Q: What is the CAS Number of Isopropyl Phenazone Q: What is the storage condition of Isopropyl Phenazone (-)-Asparagine Propyphenazon Resveratrol Impurity 39(Oxyresveratrol 3'-O-β-D-glucopyranoside)