Propyphenazone
- CAS No.
- 479-92-5
- Chemical Name:
- Propyphenazone
- Synonyms
- Budirol;Causyth;Larodon;Cibalgina;Isopyrine;Isopropchin;Isopropyrine;Propyphenazon;PROPYPHENAZONE;(-)-Asparagine
- CBNumber:
- CB5193729
- Molecular Formula:
- C14H18N2O
- Molecular Weight:
- 230.31
- MDL Number:
- MFCD00053368
- MOL File:
- 479-92-5.mol
- MSDS File:
- SDS
Melting point | 102-105°C |
---|---|
Boiling point | 372.3°C (rough estimate) |
Density | 1.0371 (rough estimate) |
refractive index | 1.5500 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methylene chloride. |
pka | 1.46±0.65(Predicted) |
form | Solid |
color | White to Off-White |
Water Solubility | 743.6g/L(25.35 ºC) |
Merck | 14,7871 |
BRN | 204533 |
Stability | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 479-92-5(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | OED8FV75PY |
ATC code | N02BB04 |
NIST Chemistry Reference | Propyphenazone(479-92-5) |
EPA Substance Registry System | 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl- (479-92-5) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 36/37/38-22 | |||||||||
Safety Statements | 26-36/37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | CD2800000 | |||||||||
HS Code | 2933.39.9200 | |||||||||
NFPA 704 |
|
Propyphenazone price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | PHR1389 | Propyphenazone Pharmaceutical Secondary Standard; Certified Reference Material | 479-92-5 | 1g | $97.5 | 2024-03-01 | Buy |
TCI Chemical | I0656 | 4-Isopropylantipyrine >98.0%(GC) | 479-92-5 | 25g | $64 | 2024-03-01 | Buy |
Sigma-Aldrich | P3750000 | Propyphenazone European Pharmacopoeia (EP) Reference Standard | 479-92-5 | p3750000 | $153 | 2024-03-01 | Buy |
TRC | P838380 | Propyphenazone | 479-92-5 | 50g | $875 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0007224 | PROPYPHENAZONE 95.00% | 479-92-5 | 25G | $950 | 2021-12-16 | Buy |
Propyphenazone Chemical Properties,Uses,Production
Description
This uncharacterized alkaloid has been described by Hartsen as occurring in Iso_x0002_pyrum thalictroides L. No chemical or physical characteristics are known.
Chemical Properties
solid
Uses
Analgesic; antipyretic; anti-inflammatory.
Definition
ChEBI: A pyrazolone derivative that is antipyrine substituted at C-4 by an isopropyl group.
brand name
539 grippe-dragees;Amipylo-n;Balpiren;Baukal;Caffalgina;Camoplex;Cantacin;Cerebrol;Daturmed;Degripol;Dentocaps a;Dim-antos;Dolibral;Dolo-mineuron;Dysmalgin;Ejcopyrin;Epizon;Escomen;Estesina;Fd 8;Febral;Finigripp;Grippocaps;Heaven;Infantex;Influvit;Isopronazon;Kavapyret;Kuronde;Lysadestat;Mamaslu;Milneuron;Myo-europan;Neuramin;Neuridal;Neuro-spondryl;Nodiras;Noric;Otobacid;Pfeil;Reomin;Retamex;Rheumanol;Rhinivict;Sanalgin-p;Saridon neu;Saridone;Sedospin;Servalgin;Sonotryl;Spalt;Spongamed;Stona;Synpyrin;Vivcet;Wauco-sin;Wecontrin.
World Health Organization (WHO)
Propyphenazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1951 for the treatment of rheumatic disorders. As it is structurally related to aminophenazone it has been associated with severe blood dyscrasias. However, it cannot be transformed into potentially carcinogenic nitrosamines and has therefore been widely used as a replacement drug for aminophenazone. In certain countries, products containing propyphenazone have now been restricted in their indications, whereas in others they are still available, sometimes as over-the-counter preparations. See also WHO comment for aminophenazone.
Clinical Use
Propyphenazone is a derivative of phenazone and has a similar analgesic and antipyretic action. It is used as a monocompound as well as in multi-ingredient preparations.
References
Hartsen., J. Chem. Soc., 511 (1873) Mirande., Compt. rend., 168,316 (1919)
Propyphenazone Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
Casorganics US Corp | +17326109938 | sales@casorganics.com | CHINA | 174 | 58 |
Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from Propyphenazone manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-29 | Propyphenazone
479-92-5
|
US $0.00 / Kg/Drum | 1KG | 98%min | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-11-19 | Propyphenazone
479-92-5
|
US $40.00 / g | 99.81% | 10g | TargetMol Chemicals Inc. | |||
2024-10-11 | Propyphenazone
479-92-5
|
US $1.90 / KG | 1KG | 99% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD |
- Propyphenazone
479-92-5
- US $0.00 / Kg/Drum
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- Propyphenazone
479-92-5
- US $40.00 / g
- 99.81%
- TargetMol Chemicals Inc.
- Propyphenazone
479-92-5
- US $1.90 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
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