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2-(Trimethylsilyl)thiazole

CAS No.
79265-30-8
Chemical Name:
2-(Trimethylsilyl)thiazole
Synonyms
2-TST;Dondoni;Dondoni reagent;2-(trimethyl)thiazole;2-TRIMETHYLSILYTHIAZOLE;2-THIAZOLYTRIMETHYLSILANE;2-Thiazolyltrimethylsilane;2-(TRIMETHYLSILYL)THIAZOLE;2-TRIMETHYLSILANYL-THIAZOLE;trimethyl(2-thiazolyl)silane
CBNumber:
CB5194791
Molecular Formula:
C6H11NSSi
Molecular Weight:
157.31
MDL Number:
MFCD00066274
MOL File:
79265-30-8.mol
Last updated:2023-04-23 13:52:06

2-(Trimethylsilyl)thiazole Properties

Boiling point 56-57 °C10 mm Hg(lit.)
Density 0.985 g/mL at 25 °C(lit.)
refractive index n20/D 1.497(lit.)
Flash point 135 °F
storage temp. Inert atmosphere,2-8°C
solubility THF: very soluble(lit.)
form Liquid
pka 2.91±0.10(Predicted)
color Clear colorless to slightly yellow
Specific Gravity 0.99
Water Solubility IMMISCIBLE
Hydrolytic Sensitivity 7: reacts slowly with moisture/water
BRN 3538017
CAS DataBase Reference 79265-30-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS02
Signal word  Warning
Hazard statements  H227-H315-H319-H226-H335
Precautionary statements  P261-P303+P361+P353-P305+P351+P338-P405-P501a-P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  23-24/25-26
RIDADR  1993
WGK Germany  3
10-21
HazardClass  3
PackingGroup  III
HS Code  29341000
NFPA 704
1
0 0

2-(Trimethylsilyl)thiazole price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical T1299 2-Trimethylsilylthiazole >95.0%(GC) 79265-30-8 1mL $53 2024-03-01 Buy
TCI Chemical T1299 2-Trimethylsilylthiazole >95.0%(GC) 79265-30-8 5mL $210 2024-03-01 Buy
Alfa Aesar B21903 2-(Trimethylsilyl)thiazole, 97% 79265-30-8 5g $159.65 2024-03-01 Buy
Alfa Aesar B21903 2-(Trimethylsilyl)thiazole, 97% 79265-30-8 1g $51.2 2021-12-16 Buy
Alfa Aesar B21903 2-(Trimethylsilyl)thiazole, 97% 79265-30-8 25g $661.65 2024-03-01 Buy
Product number Packaging Price Buy
T1299 1mL $53 Buy
T1299 5mL $210 Buy
B21903 5g $159.65 Buy
B21903 1g $51.2 Buy
B21903 25g $661.65 Buy

2-(Trimethylsilyl)thiazole Chemical Properties,Uses,Production

Chemical Properties

Colorless to light yellow liqui

Physical properties

bp 51–53 °C/10 mmHg; d 0.992 g mL?1; nD 1.4980.

Uses

2-(Trimethylsilyl)thiazole is used as formyl anion equivalent; effective one-carbon homologating reagent of alkoxy aldehydes, amino aldehydes, and dialdoses.It takes part in the reactions of Homologation of Aldehydes, Metalation and Reactivity with Electrophiles, Cross-coupling Reactions, etc.

Preparation

Although 2-(trimethylsilyl)thiazole (1) is commercially available, it can be easily prepared on a multigram scale from 2-bromothiazole, n-butyllithium, and chlorotrimethylsilane as shown in eq 1.

79265-30-8 synthesis

Global( 205)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
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Henan Tianfu Chemical Co.,Ltd.
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ATK CHEMICAL COMPANY LIMITED
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Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
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Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9636 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58

View Lastest Price from 2-(Trimethylsilyl)thiazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(Trimethylsilyl)thiazole pictures 2019-07-06 2-(Trimethylsilyl)thiazole
79265-30-8
US $1.00 / kg 1kg 98% 100KG Career Henan Chemical Co
2-TST 2-THIAZOLYTRIMETHYLSILANE 2-Thiazolyltrimethylsilane Thiazole, 2-(trimethylsilyl)- 2-(trimethyl)thiazole 2-TRIMETHYLSILYTHIAZOLE Dondoni 2-Thiazolyltrimethylsilane, 2-TST 2-(Trimethylsilyl)thiazole,96% Dondoni reagent 2-(TriMethylsilyl)thiazole, 96% 1ML 2-(TriMethylsilyl)thiazole, 96% 5ML (1,3-Thiazol-2-yl)trimethylsilane 2-TRIMETHYLSILANYL-THIAZOLE 2-(TRIMETHYLSILYL)-1,3-THIAZOLE 2-(TRIMETHYLSILYL)THIAZOLE trimethyl(2-thiazolyl)silane 2-Trimethylsilyl thiazole, 96%, for synthesis TIANFUCHEM--79265-30-8--2-(Trimethylsilyl)thiazole trimethyl(1,3-thiazol-2-yl)silane 79265-30-8 79263-30-8 C6H4NSSi Building Blocks Si-(C)4 Compounds Si (Classes of Silicon Compounds) Silicon Compounds (for Synthesis) Heterocyclic Building Blocks Thiazoles Thiazoles, Isothiazoles & Benzothiazoles API intermediates Si (Classes of Silicon Compounds) Si-(C)4 Compounds Silicon Compounds (for Synthesis) Synthetic Organic Chemistry Building Blocks C3 to C7 Chemical Synthesis Heterocyclic Building Blocks Thiazoles Thiazoles, Isothiazoles &Benzothiazoles