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Ganoderenic acid D

CAS No.
100665-43-8
Chemical Name:
Ganoderenic acid D
Synonyms
Ganoderenic acid d;Apoptosis,Inhibitor,inhibit,Ganoderenic acid D;(20E)-7β-Hydroxy-3,11,15,23-tetraoxolanosta-8,20(22)-diene-26-oic acid;(20E)-7β-Hydroxy-3,11,15,23-tetraoxo-5α-lanosta-8,20(22)-dien-26-oic acid;(7beta,20E)-7-Hydroxy-3,11,15,23-tetraoxolanosta-8,20(22)-dien-26-oic acid;Lanosta-8,20(22)-dien-26-oic acid, 7-hydroxy-3,11,15,23-tetraoxo-, (7β,20E)-;(E)-6-((5R,7S,10S,13R,14R,17R)-7-Hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxohept-5-enoic acid
CBNumber:
CB52192797
Molecular Formula:
C30H40O7
Molecular Weight:
512.6344
MDL Number:
MFCD32197329
MOL File:
100665-43-8.mol
MSDS File:
SDS
Last updated:2024-11-19 20:33:22

Ganoderenic acid D Properties

Melting point 218-220℃
Boiling point 702.3±60.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka 4.63±0.23(Predicted)
color White to off-white

Ganoderenic acid D price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 300301 Ganoderenic acid D 100665-43-8 10mg $490 2021-12-16 Buy
Biorbyt Ltd orb259246 Ganoderenic acid D 98% 100665-43-8 5mg $654.5 2021-12-16 Buy
AvaChem 3481 Ganoderenic acid D 100665-43-8 10mg $590 2021-12-16 Buy
AvaChem 3481 Ganoderenic acid D 100665-43-8 2mg $249 2021-12-16 Buy
Arctom CFN90300 GanoderenicacidD ≥98% 100665-43-8 10mg $476 2021-12-16 Buy
Product number Packaging Price Buy
300301 10mg $490 Buy
orb259246 5mg $654.5 Buy
3481 10mg $590 Buy
3481 2mg $249 Buy
CFN90300 10mg $476 Buy

Ganoderenic acid D Chemical Properties,Uses,Production

Uses

Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. It inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells. It also induces HeLa human cervical carcinoma apoptosis.

Definition

ChEBI: Ganoderenic acid D is a triterpenoid.

Biological Activity

Ganoderenic acid D is a triterpenoid originally isolated from G. lucidum and has diverse biological activities. It inhibits angiotensin-converting enzyme (ACE; IC50 = 734 μM). Ganoderenic acid D is cytotoxic to HepG2 liver, HeLa cervical, and Caco-2 colon cancer cells (IC50s = 0.14, 0.18, and 0.26 mg/ml, respectively). It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50 = 13.77 μM).

Ganoderenic acid D Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 101)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
Chengdu Greenpure Biopharma CO.,Ltd
18283602253; +8618283602253 jancyzheng@gcgreenpure.com China 953 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3772 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2993 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58

View Lastest Price from Ganoderenic acid D manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ganoderenic acid D pictures 2024-11-19 Ganoderenic acid D
100665-43-8
US $220.00-92.00 / mg 99.05% 10g TargetMol Chemicals Inc.
Ganoderenic acid D pictures 2023-02-24 Ganoderenic acid D
100665-43-8
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
Ganoderenic acid D pictures 2020-01-18 Ganoderenic acid D
100665-43-8
US $3.00 / KG 1KG 98% 1kg , 5kg, 50kg Career Henan Chemical Co
  • Ganoderenic acid D pictures
  • Ganoderenic acid D
    100665-43-8
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
(20E)-7β-Hydroxy-3,11,15,23-tetraoxo-5α-lanosta-8,20(22)-dien-26-oic acid (20E)-7β-Hydroxy-3,11,15,23-tetraoxolanosta-8,20(22)-diene-26-oic acid (7beta,20E)-7-Hydroxy-3,11,15,23-tetraoxolanosta-8,20(22)-dien-26-oic acid Ganoderenic acid d Apoptosis,Inhibitor,inhibit,Ganoderenic acid D (E)-6-((5R,7S,10S,13R,14R,17R)-7-Hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxohept-5-enoic acid Lanosta-8,20(22)-dien-26-oic acid, 7-hydroxy-3,11,15,23-tetraoxo-, (7β,20E)- 100665-43-8 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract