ANTI-HUMAN IGG4
- CAS No.
- Chemical Name:
- ANTI-HUMAN IGG4
- Synonyms
- ANTI-HUMAN IGG4;ANTI-IGG4, HUMAN;ANTI-IMMUNOGLOBULIN G4, HUMAN;ANTI-HUMAN IGG4 (PFC' SPECIFIC);ANTI-IMMUNOGLOBULIN G (SUBCLASS 4);ANTI-HUMAN IGG SUBCLASS 4 ISOTYPE: IGG3;Monoclonal Anti-Human IgG4 antibody produced in mouse;Monoclonal Anti-Human IgG4 (pFcμ specific) antibody produced in mouse
- CBNumber:
- CB5222694
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00164659
- MOL File:
- Mol file
ANTI-HUMAN IGG4 price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | I9888 | Monoclonal Anti-Human IgG4 (pFc′ specific) antibody produced in mouse clone HP-6023, ascites fluid | 0.2mL | $205 | 2024-03-01 | Buy | |
| American Custom Chemicals Corporation | ATB0011173 | ANTI-HUMAN IGG4 95.00% | 5MG | $503.11 | 2021-12-16 | Buy |
ANTI-HUMAN IGG4 Chemical Properties,Uses,Production
Uses
The IUIS/WHO2 study singled out this monoclonal antibody as one of the most widely applicable IgG4 specific monoclonal antibodies. Monoclonal Anti-Human IgG4 may be used for the identification of the IgG4 subclass by various immunoassays including: ELISA, Imprint Immunofixation (IIF), Immunofluorometric Assay (IFMA), Hemagglutination (HA), Hemagglutination Inhibition (HAI), Particle Counting Immunoassay (PACIA), and detection of cytoplasmic IgG.
Uses
Monoclonal Anti-Human IgG4 (pFc′ specific) antibody can be used for immunoblotting and Indirect Immunoperoxidase Assay.
General Description
IgG4 (Immunoglobulin G4) is produced by T helper 2 cytokines. Unlike other immunoglobulin G is rare and constitutes to only 3-4 percent of the total IgG in the serum.
Biochem/physiol Actions
IgG4 (Immunoglobulin G4) antibody has reduced affinity for C1q (first component of complement q) and hence its anti-inflammatory activity differing from that of the other IgG subclasses. IgG4 antibodies are known to actively interchange Fab arms with another molecule, resulting in recombined antibodies with two different binding specificities. This exchange is considered as an important biological mechanism that contributes to its anti-inflammatory activity. IgG4 antibodies are normally noninflammatory, but autoreactive IgG4 antibodies are known to be associated with Immunoglobulin G4 (IgG4)-related disease (IgG4-RD), characterized by infiltrating lymphoplasmacytic cells and elevated serum IgG4. Increased levels of IgG4 is observed in atopic dermatitis, parasitic diseases, pemphigus vulgaris and pemphigus foliaceus.
ANTI-HUMAN IGG4 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HUMAN IGG4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Riedel-de Haen AG | -- | United States | 6773 | 87 | |
| SIGMA-RBI | -- | Switzerland | 6896 | 91 | |
| OEM Concepts | -- | United States | 540 | 50 | |
| Pierce Biotechnology, Inc. | -- | cs@piercenet.com | United States | 966 | 82 |
| Karlan Research Products Corporation | -- | info@karlan.com | United States | 420 | 51 |
| Kanto Chemical Co., Inc. | -- | reag-info@gms.kanto.co.jp | Japan | 6756 | 74 |
| Beckman Coulter, Inc. | -- | United States | 1183 | 86 | |
| Cortex Biochem, Inc. | -- | info@cortex-biochem.com | United States | 1557 | 77 |
| Caltag Laboratories | -- | caltag@caltag.com | United States | 1313 | 63 |
| BIOTREND Chemikalien GmbH | -- | jaeger@biotrend.com | Germany | 6115 | 76 |
| Supplier | Advantage |
|---|---|
| Riedel-de Haen AG | 87 |
| SIGMA-RBI | 91 |
| OEM Concepts | 50 |
| Pierce Biotechnology, Inc. | 82 |
| Karlan Research Products Corporation | 51 |
| Kanto Chemical Co., Inc. | 74 |
| Beckman Coulter, Inc. | 86 |
| Cortex Biochem, Inc. | 77 |
| Caltag Laboratories | 63 |
| BIOTREND Chemikalien GmbH | 76 |