ChemicalBook >> CAS DataBase List >>IDAZOXAN HYDROCHLORIDE
IDAZOXAN HYDROCHLORIDE
- CAS No.
- 79944-56-2
- Chemical Name:
- IDAZOXAN HYDROCHLORIDE
- Synonyms
- RX 781094A;IdazoxanHCl;Idazoxan hydrochlori;IDAZOXAN HYDROCHLORIDE;(+/-)-Idazoxan Monohydrochloride;2-(1,4-BENZODIOXAN-2-YL)-2-IMIDAZOLINE HYDROCHLORIDE;RX 781094, (±)-2-[1,4-Benzodioxan-2-yl]-2-imidazoline hydrochloride;Idazoxan hydrochloride,2-(1,4-Benzodioxan-2-yl)-2-imidazolinehydrochloride;2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-iMidazole Hydrochloride;2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-iMidazole hydrochloride
- CBNumber:
- CB5236802
- Molecular Formula:
- C11H13ClN2O2
- Molecular Weight:
- 240.69
- MDL Number:
- MFCD00069293
- MOL File:
- 79944-56-2.mol
Last updated:2024-11-19 15:53:33
| Melting point | 207-208° |
|---|---|
| storage temp. | Store at RT |
| solubility | H2O: 300 mg/mL |
| form | Powder |
| color | White to off-white |
| Water Solubility | Soluble to 100 mM in water |
| Stability | Hygroscopic |
| FDA UNII | 15394QZS7A |
IDAZOXAN HYDROCHLORIDE price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | I6138 | Idazoxan hydrochloride | 79944-56-2 | 50mg | $115 | 2024-03-01 | Buy |
| Sigma-Aldrich | I6138 | Idazoxan hydrochloride | 79944-56-2 | 100mg | $153 | 2024-03-01 | Buy |
| Sigma-Aldrich | 5.04746 | IdazoxanHydrochloride-CAS79944-56-2-Calbiochem | 79944-56-2 | 50mg | $146 | 2022-05-15 | Buy |
| Tocris | 0793 | Idazoxan hydrochloride ≥98% | 79944-56-2 | 10 | $159 | 2021-12-16 | Buy |
| Tocris | 0793 | Idazoxan hydrochloride ≥98% | 79944-56-2 | 50 | $647 | 2021-12-16 | Buy |
IDAZOXAN HYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
mp 207-209°C
Uses
Idazoxan hydrochloride has been used to study the efficacy of antidepressant treatments that interact with multiple neurotransmitter systems.
Uses
Antiparkinsonian;Alpha2 agonist
Uses
An α-adrenoceptor antagonist; in rat brain Idazoxan is a pure antagonist and it has a selectivity for α2- over α1-receptors markedly superior to Piperoxane, Yohimbine, or Rauwolscine. Antiparkinsonian.
Biological Activity
α 2 -adrenoceptor antagonist, and I 2 ligand, selective over I 1 sites (pK i values are 5.90, 7.22, 8.01, 7.43, and 7.7 for I 1 , I 2 , α 2A , α 2B , and α 2C receptors respectively).
Biochem/physiol Actions
α2-adrenoceptor antagonist; I2?imidazoline receptor agonist; I1?imidazoline receptor antagonist. Idazoxan can antagonize various behaviors generated by ethanol in a preclinical setting. It possesses neuroprotective activity against spinal cord injury, resulted due to experimental autoimmune encephalomyelitis (EAE) in mouse, an animal modal of multiple sclerosis (MS).
Synthesis of IDAZOXAN HYDROCHLORIDE from 2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBONITRILE and Ethylenediamine
IDAZOXAN HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
IDAZOXAN HYDROCHLORIDE Suppliers
Global( 69)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19885 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| shanghai | 17354719950 | sales@fultrachem.com | China | 17 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94657 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
View Lastest Price from IDAZOXAN HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Idazoxan hydrochloride
79944-56-2
|
US $30.00-59.00 / mg | 99.84% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-19 | Idazoxan hydrochloride
79944-56-2
|
US $30.00-59.00 / mg | 99.84% | 10g | TargetMol Chemicals Inc. |
-
- Idazoxan hydrochloride
79944-56-2
- US $30.00-59.00 / mg
- 99.84%
- TargetMol Chemicals Inc.
-
- Idazoxan hydrochloride
79944-56-2
- US $30.00-59.00 / mg
- 99.84%
- TargetMol Chemicals Inc.
79944-56-2(IDAZOXAN HYDROCHLORIDE)Related Search:
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1of4
(+/-)-Idazoxan Monohydrochloride
2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-iMidazole Hydrochloride
RX 781094A
2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-4,5-dihydro-1H-iMidazole hydrochloride
IDAZOXAN HYDROCHLORIDE
2-(1,4-BENZODIOXAN-2-YL)-2-IMIDAZOLINE HYDROCHLORIDE
IdazoxanHCl
RX 781094, (±)-2-[1,4-Benzodioxan-2-yl]-2-imidazoline hydrochloride
Idazoxan hydrochloride,2-(1,4-Benzodioxan-2-yl)-2-imidazolinehydrochloride
Idazoxan hydrochlori
RX781094,inhibit,Adrenergic Receptor,RX-781094,Idazoxan,Inhibitor,Beta Receptor,Idazoxan hydrochloride,Imidazoline Receptor
79944-56-2
79944-65-2
Adrenoceptor
Aromatics
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals