PROTEIN TYROSINE PHOSPHATASE 1B
- CAS No.
- Chemical Name:
- PROTEIN TYROSINE PHOSPHATASE 1B
- Synonyms
- PTP1B;PTPN1;PTP-1B, AGAROSE;Human PTPN1 Protein, His Tag;PTP1B full length Active human;PROTEIN TYROSINE PHOSPHATASE 1B;PTP1B (1-321)/PTPN1 Active human;PTP1B (1-321)/PTPN1 Active from rat;PROTEIN TYROSINE PHOSPHATASE 1B HUMAN;PTP1B (1-321)/PTPN1 Active from mouse
- CBNumber:
- CB5237056
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01635664
- MOL File:
- Mol file
| storage temp. | −70°C |
|---|---|
| form | buffered aqueous solution |
| biological source | rabbit |
| Specific Activity | ≥20units/mg protein |
| FDA UNII | GJD3Q7KT3S |
PROTEIN TYROSINE PHOSPHATASE 1B price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4502525 | Anti-PTP1B antibody produced in rabbit affinity isolated antibody | 100μg | $506 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB1306060 | ANTI-PTP1B antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 400μL | $481 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB1306059 | ANTI-PTP1B (N-TERMINAL) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 400μl | $481 | 2024-03-01 | Buy | |
| Sigma-Aldrich | P6244 | Protein Tyrosine Phosphatase 1B human recombinant, expressed in E. coli | 50μg | $827 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SRP0215 | PTP1B full length Active human recombinant, expressed in E. coli, ≥55% (SDS-PAGE) | 20μG | $460 | 2023-06-20 | Buy |
PROTEIN TYROSINE PHOSPHATASE 1B Chemical Properties,Uses,Production
Uses
Protein Tyrosine Phosphatase 1B (PTP1B) human has been used in treating cell lysate prior to immunoprecipitation and protein pull-down studies. It has also been used in PTP1B activity assay and also for the evaluation of inhibitors like betulinic acid (BA) and sodium orthovanadate (Na3VO4), and 6-chloro-3-formyl-7-methylchromone (CFM) on PTP1B.
General Description
Protein tyrosine phosphatase 1B human (PTP1B) is encoded by the gene PTPN1. In human chromosome, the gene PTPN1 is localized on 20q13.13. The protein has 37 kDa catalytic domain and the C-terminal hydrophobic residues targets the protein to the cytoplasmic side of the endoplasmic reticulum membrane.
Biochem/physiol Actions
PTP-1B is a recombinant, non-transmembrane protein expressed in E. coli containing amino acid residues 1-322 of human PTP-1B. It has a molecular mass of 37.4 kDa. It is an abundant intracellular enzyme that is thought to act as a negative regulator of certain signaling pathways. It dephosphorylates tyrosine-phosphorylated proteins and peptides, and is usually localized in the cytostolic domain of the ER.
PROTEIN TYROSINE PHOSPHATASE 1B Preparation Products And Raw materials
Raw materials
Preparation Products
PROTEIN TYROSINE PHOSPHATASE 1B Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10457 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9966 | 58 |
| zsbio | 400-810-9781 | zsbio@qq.com | CHINA | 2887 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 58 |
| Shanghai Huzhen Industrial Co., LTD | 58 |
| zsbio | 58 |