ChemicalBook >> CAS DataBase List >>BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)-

BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)-

BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- structure

CAS No.: 918430-49-6

Chemical Name:: BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)-

Synonyms: (Rac)-TTA-P2;3,5-Dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-dimethyl-2H-pyran-4-yl)methyl]-4-piperidinyl]methyl]ben;3,5-dichloro-N-((1-((2,2-diMethyltetrahydro-2H-pyran-4-yl)Methyl)-4-fluoropiperidin-4-yl)Methyl)benzaMide;3,5-Dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-dimethyl-2H-pyran-4-yl)methyl]-4-piperidinyl]methyl]Benzamide;BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-;BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)-

CBNumber:: CB52468540

Molecular Formula:: C21H29Cl2FN2O2

Molecular Weight:: 431.37

MDL Number:: MFCD11977740

MOL File:: 918430-49-6.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

Request For Quotation

BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- Properties

Boiling point	510.1±50.0 °C(Predicted)
Density	1.25±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Soluble in DMSO (10 mg/ml)
form	solid
pka	13.65±0.46(Predicted)
color	Tan
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AK Scientific	2018CW	3,5-Dichloro-N-[[1-[(2,2-dimethyloxan-4-yl)methyl]-4-fluoropiperidin-4-yl]methyl]benzamide	918430-49-6	100mg	$111	2021-12-16	Buy
AK Scientific	2018CW	3,5-Dichloro-N-[[1-[(2,2-dimethyloxan-4-yl)methyl]-4-fluoropiperidin-4-yl]methyl]benzamide	918430-49-6	250mg	$142	2021-12-16	Buy
AK Scientific	2018CW	3,5-Dichloro-N-[[1-[(2,2-dimethyloxan-4-yl)methyl]-4-fluoropiperidin-4-yl]methyl]benzamide	918430-49-6	1g	$254	2021-12-16	Buy
Chemenu	CM255767	3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide 95+%	918430-49-6	1g	$514	2021-12-16	Buy
Crysdot	CD11015926	3,5-Dichloro-N-((1-((2,2-dimethyltetrahydro-2H-pyran-4-yl)methyl)-4-fluoropiperidin-4-yl)methyl)benzamide 97%	918430-49-6	1g	$545	2021-12-16	Buy

Product number	Packaging	Price	Buy
2018CW	100mg	$111	Buy
2018CW	250mg	$142	Buy
2018CW	1g	$254	Buy
CM255767	1g	$514	Buy
CD11015926	1g	$545	Buy

BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- Chemical Properties,Uses,Production

Description

TTA-P2 (918430-49-6) is a potent (IC50 = 100 nM), specific, and reversible antagonist of T-type calcium channels with no activity at high voltage calcium channels.1,2 Highly potent in two animal models of pain in vivo.3

References

Shipe et al. (2008), Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonist; J. Med. Chem., 51 3692 Dreyfus et al. (2010), Selective T-type calcium channel block in thalamic neurons reveals channel redundancy and physiological impact of I(T)window; J. Neurosci., 30 99 Choe et al. (2011), TTA-P2 is a potent and selective blocker of T-type calcium channels in rat sensory neurons and a novel antinociceptive agent; Mol. Pharmacol., 80 900

BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- Preparation Products And Raw materials

Raw materials

Preparation Products

BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- Suppliers

Global( 18)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30250	58
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	20356	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Acesys Pharmatech	18860950986	tangmanman@zenjipharma.com	China	1735	55
Shanghai Balmxy Pharmaceutical Co., Ltd	021-24206007 13764915196	sales@balmxy.com	China	6765	55
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 13675144456	sean.lv@synzest.com	China	11442	58
Shanghai Haohong Pharmaceutical Co., Ltd.	400-8210725 4008210725	malulu@leyan.com	China	40037	58
Shanghai Universal Biotech Co.,Ltd	18768175414	gaojun@univ-bio.com	China	24998	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	62163	58
Bide Pharmatech Ltd.	400-6005915	sales@picasso-e.com	China	39661	58

Supplier	Advantage
Career Henan Chemica Co	58
CD Chemical Group Limited	58
Amadis Chemical Company Limited	58
Acesys Pharmatech	55
Shanghai Balmxy Pharmaceutical Co., Ltd	55
Nanjing Shizhou Biology Technology Co.,Ltd	58
Shanghai Haohong Pharmaceutical Co., Ltd.	58
Shanghai Universal Biotech Co.,Ltd	58
Bide Pharmatech Ltd.	58
Bide Pharmatech Ltd.	58

918430-49-6(BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)-)Related Search:

Tigecycline AZ20 BI 2536 Fruquintinib|HMPL-013

BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]- BENZAMIDE, 3,5-DICHLORO-N-[[4-FLUORO-1-[(TETRAHYDRO-2,2-DIMETHYL-2H-PYRAN-4-YL)METHYL]-4-PIPERIDINYL]METHYL]-, (+)- 3,5-Dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-dimethyl-2H-pyran-4-yl)methyl]-4-piperidinyl]methyl]Benzamide 3,5-dichloro-N-((1-((2,2-diMethyltetrahydro-2H-pyran-4-yl)Methyl)-4-fluoropiperidin-4-yl)Methyl)benzaMide 3,5-Dichloro-N-[[4-fluoro-1-[(tetrahydro-2,2-dimethyl-2H-pyran-4-yl)methyl]-4-piperidinyl]methyl]ben (Rac)-TTA-P2 918430-49-6 C21H29Cl2FN2O2