ChemicalBook >> CAS DataBase List >>2-oxa-6-azaspiro[3.4]octane

2-oxa-6-azaspiro[3.4]octane

CAS No.
220290-68-6
Chemical Name:
2-oxa-6-azaspiro[3.4]octane
Synonyms
2-oxa-7-azaspiro[3.4]octane;2-oxa-6-azaspiro[3.4]octane;2-Oxa-6-azaspiro[3.4]octa...;2-Oxa-6-azaspiro[3.4]octane,95%;2-Oxa-6-azaspiro[3.4]octane (9CI, ACI);2-oxa-6-azaspiro[3.4]octane, hemioxalate salt
CBNumber:
CB52506037
Molecular Formula:
C6H11NO
Molecular Weight:
113.16
MDL Number:
MFCD14586455
MOL File:
220290-68-6.mol
Last updated:2023-10-20 13:44:49

2-oxa-6-azaspiro[3.4]octane Properties

Boiling point 187℃
Density 1.08
Flash point 63°(145°F)
storage temp. 2-8°C(protect from light)
pka 10.55±0.20(Predicted)
Water Solubility Soluble in water.
InChI InChI=1S/C6H11NO/c1-2-7-3-6(1)4-8-5-6/h7H,1-5H2
InChIKey ZHAIMJRKJKQNQI-UHFFFAOYSA-N
SMILES C1C2(CCNC2)CO1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Danger
Hazard statements  H227-H315-H319-H335
Precautionary statements  P210e-P261-P280a-P305+P351+P338-P405-P501a
HS Code  29339900
NFPA 704
2
2 0

2-oxa-6-azaspiro[3.4]octane price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar H57579 2-Oxa-6-azaspiro[3.4]octane, 95% 220290-68-6 250mg $324.65 2024-03-01 Buy
Alfa Aesar H57579 2-Oxa-6-azaspiro[3.4]octane, 95% 220290-68-6 500mg $592.65 2024-03-01 Buy
Usbiological 285953 2-Oxa-6-azaspiro[3.4]octane 220290-68-6 25mg $359 2021-12-16 Buy
TRC O990125 2-Oxa-6-Azaspiro[3.4]Octane 220290-68-6 10mg $65 2021-12-16 Buy
SynQuest Laboratories 4H31-1-10 2-Oxa-6-azaspiro[3.4]octane 220290-68-6 250mg $295 2021-12-16 Buy
Product number Packaging Price Buy
H57579 250mg $324.65 Buy
H57579 500mg $592.65 Buy
285953 25mg $359 Buy
O990125 10mg $65 Buy
4H31-1-10 250mg $295 Buy

2-oxa-6-azaspiro[3.4]octane Chemical Properties,Uses,Production

Uses

2-Oxa-6-azaspiro[3.4]octane is involved in the preparation of azaspirocycle or azetidine substituted 4-anilinoquinazoline derivatives, which exhibits epidermal growth factor receptor (EGFR) inhibitory activities.

Application

2-Oxa-6-Azaspiro[3.4]Octane Hydrochloride may be useful in the preparation of aminocyanopyridine derivatives for the prevention or treatment of cancer or inflammatory diseases.

Synthesis

Tert-butyl 2-oxa-6-azaspiro[3.4]octane-6-carboxylate (86mg, 0.4mmol) was dissolved in dichloromethane (1mL), trifluoroacetic acid (2mL) was added to the system at room temperature, and the reaction solution was heated at 60°C for 2h. The reaction solution was cooled to room temperature and concentrated under reduced pressure to obtain crude product 2-oxa-6-azaspiro[3.4]octane.
2-oxa-6-azaspiro[3.4]octane

2-oxa-6-azaspiro[3.4]octane Preparation Products And Raw materials

Raw materials

Preparation Products

2-oxa-6-azaspiro[3.4]octane Suppliers

Global( 85)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
Jinan Liheng Biotechnology Co., Ltd.
15865262812 info@lihengpharm.com CHINA 938 58
Wuxi Rejoys chemical Technology Co., Ltd.
0510-86103381 sales@rejoyschem.com CHINA 976 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15352 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com China 52849 58
PT CHEM GROUP LIMITED
peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49978 58
Protheragen-ING
+16313385890 info@protheragen-ing.com United States 3868 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43340 58

View Lastest Price from 2-oxa-6-azaspiro[3.4]octane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-oxa-6-azaspiro[3.4]octane pictures 2020-01-13 2-oxa-6-azaspiro[3.4]octane
220290-68-6
US $1.00 / KG 1KG 98%-99.9% 100kg Career Henan Chemical Co
2-oxa-6-azaspiro[3.4]octane 2-Oxa-6-azaspiro[3.4]octa... 2-oxa-6-azaspiro[3.4]octane, hemioxalate salt 2-Oxa-6-azaspiro[3.4]octane,95% 2-oxa-7-azaspiro[3.4]octane 2-Oxa-6-azaspiro[3.4]octane (9CI, ACI) 220290-68-6