2-oxa-6-azaspiro[3.4]octane
- CAS No.
- 220290-68-6
- Chemical Name:
- 2-oxa-6-azaspiro[3.4]octane
- Synonyms
- 2-oxa-7-azaspiro[3.4]octane;2-oxa-6-azaspiro[3.4]octane;2-Oxa-6-azaspiro[3.4]octa...;2-Oxa-6-azaspiro[3.4]octane,95%;2-Oxa-6-azaspiro[3.4]octane (9CI, ACI);2-oxa-6-azaspiro[3.4]octane, hemioxalate salt
- CBNumber:
- CB52506037
- Molecular Formula:
- C6H11NO
- Molecular Weight:
- 113.16
- MDL Number:
- MFCD14586455
- MOL File:
- 220290-68-6.mol
Boiling point | 187℃ |
---|---|
Density | 1.08 |
Flash point | 63°(145°F) |
storage temp. | 2-8°C(protect from light) |
pka | 10.55±0.20(Predicted) |
Water Solubility | Soluble in water. |
InChI | InChI=1S/C6H11NO/c1-2-7-3-6(1)4-8-5-6/h7H,1-5H2 |
InChIKey | ZHAIMJRKJKQNQI-UHFFFAOYSA-N |
SMILES | C1C2(CCNC2)CO1 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Danger | |||||||||
Hazard statements | H227-H315-H319-H335 | |||||||||
Precautionary statements | P210e-P261-P280a-P305+P351+P338-P405-P501a | |||||||||
HS Code | 29339900 | |||||||||
NFPA 704 |
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2-oxa-6-azaspiro[3.4]octane price More Price(16)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Alfa Aesar | H57579 | 2-Oxa-6-azaspiro[3.4]octane, 95% | 220290-68-6 | 250mg | $324.65 | 2024-03-01 | Buy |
Alfa Aesar | H57579 | 2-Oxa-6-azaspiro[3.4]octane, 95% | 220290-68-6 | 500mg | $592.65 | 2024-03-01 | Buy |
Usbiological | 285953 | 2-Oxa-6-azaspiro[3.4]octane | 220290-68-6 | 25mg | $359 | 2021-12-16 | Buy |
TRC | O990125 | 2-Oxa-6-Azaspiro[3.4]Octane | 220290-68-6 | 10mg | $65 | 2021-12-16 | Buy |
SynQuest Laboratories | 4H31-1-10 | 2-Oxa-6-azaspiro[3.4]octane | 220290-68-6 | 250mg | $295 | 2021-12-16 | Buy |
2-oxa-6-azaspiro[3.4]octane Chemical Properties,Uses,Production
Uses
2-Oxa-6-azaspiro[3.4]octane is involved in the preparation of azaspirocycle or azetidine substituted 4-anilinoquinazoline derivatives, which exhibits epidermal growth factor receptor (EGFR) inhibitory activities.
Application
2-Oxa-6-Azaspiro[3.4]Octane Hydrochloride may be useful in the preparation of aminocyanopyridine derivatives for the prevention or treatment of cancer or inflammatory diseases.
Synthesis
Tert-butyl 2-oxa-6-azaspiro[3.4]octane-6-carboxylate (86mg, 0.4mmol) was dissolved in dichloromethane (1mL), trifluoroacetic acid (2mL) was added to the system at room temperature, and the reaction solution was heated at 60°C for 2h. The reaction solution was cooled to room temperature and concentrated under reduced pressure to obtain crude product 2-oxa-6-azaspiro[3.4]octane.
2-oxa-6-azaspiro[3.4]octane Preparation Products And Raw materials
Raw materials
Preparation Products
2-oxa-6-azaspiro[3.4]octane Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
Jinan Liheng Biotechnology Co., Ltd. | 15865262812 | info@lihengpharm.com | CHINA | 938 | 58 |
Wuxi Rejoys chemical Technology Co., Ltd. | 0510-86103381 | sales@rejoyschem.com | CHINA | 976 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15352 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
PT CHEM GROUP LIMITED | peter68@ptchemgroup.com | China | 35425 | 58 | |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49978 | 58 |
Protheragen-ING | +16313385890 | info@protheragen-ing.com | United States | 3868 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
View Lastest Price from 2-oxa-6-azaspiro[3.4]octane manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-01-13 | 2-oxa-6-azaspiro[3.4]octane
220290-68-6
|
US $1.00 / KG | 1KG | 98%-99.9% | 100kg | Career Henan Chemical Co |
- 2-oxa-6-azaspiro[3.4]octane
220290-68-6
- US $1.00 / KG
- 98%-99.9%
- Career Henan Chemical Co