5(6)-Carboxyfluorescein
- CAS No.
- 72088-94-9
- Chemical Name:
- 5(6)-Carboxyfluorescein
- Synonyms
- 5(6)-FAM;DCFA;5(6)-Carboxyfluoresc;5(6)-CARBOXYLUORESCEIN;4(5)-CARBOXYFLUORESCEIN;5(6)-CARBOXYFLUORESCEIN;5(6)-Carboxyfluoresceine];4(5)-Carboxyfluoresceine];Fluoresceincarboxylic Acid;5(6)-CARBOXYFLUORESCEIN 99%
- CBNumber:
- CB5257173
- Molecular Formula:
- C42H24O14
- Molecular Weight:
- 752.63
- MDL Number:
- MFCD00151081
- MOL File:
- 72088-94-9.mol
- MSDS File:
- SDS
| Melting point | 275 °C |
|---|---|
| Boiling point | 464.9°C (rough estimate) |
| Density | 1.3418 (rough estimate) |
| refractive index | 1.6380 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Sparingly), Methanol (Slightly, Heated) |
| form | Solid |
| color | Light Yellow to Dark Brown |
| Water Solubility | slightly soluble |
| InChIKey | CPRVUBZYHZGASQ-UHFFFAOYSA-N |
| SMILES | C12(OC(=O)C3C=CC(C(=O)O)=CC1=3)C1=CC=C(O)C=C1OC1C=C(O)C=CC2=1.C12(OC(=O)C3C=C(C(=O)O)C=CC1=3)C1=CC=C(O)C=C1OC1C=C(O)C=CC2=1 |
| EPA Substance Registry System | Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylic acid, 3',6'-dihydroxy-3-oxo- (72088-94-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36-36/37/38-20/21/22 | |||||||||
| Safety Statements | 37/39-26-36-22 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29322090 | |||||||||
| NFPA 704 |
|
5(6)-Carboxyfluorescein price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.51082 | 5(6)-Carboxyfluorescein Novabiochem? | 72088-94-9 | 1g | $58 | 2024-03-01 | Buy |
| Sigma-Aldrich | 8.51082 | 5(6)-Carboxyfluorescein Novabiochem? | 72088-94-9 | 5G | $194 | 2024-03-01 | Buy |
| Sigma-Aldrich | 21877 | 5(6)-Carboxyfluorescein BioReagent, suitable for fluorescence, ≥95% (HPLC) | 72088-94-9 | 1g | $60.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | 21877 | 5(6)-Carboxyfluorescein BioReagent, suitable for fluorescence, ≥95% (HPLC) | 72088-94-9 | 5G | $207 | 2024-03-01 | Buy |
| Alfa Aesar | L13439 | 5(6)-Carboxyfluorescein, mixture of isomers, 97% | 72088-94-9 | 250mg | $51.65 | 2024-03-01 | Buy |
5(6)-Carboxyfluorescein Chemical Properties,Uses,Production
Description
5(6)-Carboxyfluorescein is a mixture of 5-carboxy and 6-carboxy derivatives of fluorescein. It is commonly used to label biomolecules through a reaction involving the carboxyl group. Unlike its succinimidyl ester derivative CFSE , 5(6)-carboxyfluorescein is membrane impermeant. As a result, it can be used in studies of membrane permeability. 5(6)-Carboxyfluorescein displays excellent fluorescence (excitation/emission at 492/514 nm, respectively), and its excitation maximum closely matches the 488 nm spectral line of argon-ion lasers.
Chemical Properties
Dark-Orange to Brown Solid
Uses
As a popular probe of determination of intracellular pH, 5(6)-Carboxyfluoresceincan be used as useful reagent for the preparation of hydrolytically stable fluorescent conjugates and a useful starting material for the synthesis of other fluorescein-derives reagent
Uses
5(6)-FAM, A useful reagent for the preparation of hydrolytically stable fluorescent conjugates and is a useful starting material for the synthesis of other fluorescein-derives reagent.
Uses
A popular probe of determination of intracellular pH.
Definition
ChEBI: 5(6)-carboxyfluorescein is a commercially available mixture of 5-carboxyfluorescein and 6-carboxyfluorescein isomers. A fluorescent dye, it is commonly used as a tracer agent. It has a role as a tracer and a fluorescent dye. It contains a 5-carboxyfluorescein and a 6-carboxyfluorescein.
Solubility in organics
5(6)-Carboxyfluorescein is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide. The solubility of 5(6)-carboxyfluorescein in these solvents is approximately 5, 0.5, and 1 mg/ml, respectively.
5(6)-Carboxyfluorescein Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hongxiong | +undefined18915499068 | Suzhouhongxiong@163.com | China | 120 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12832 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5857 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18148 | 58 |
| Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3009 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20274 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 970 | 58 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18750 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32956 | 60 |
View Lastest Price from 5(6)-Carboxyfluorescein manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-01-10 | 5(6)-Carboxyfluorescein
72088-94-9
|
US $30.00 / kg | 1kg | 98% | 3000kg | hebei hongtan Biotechnology Co., Ltd | |
 |
2024-11-18 | 5(6)-Carboxyfluorescein
72088-94-9
|
US $29.00 / mg | 98.85% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-10-28 | 5(6)-Carboxyfluorescein
72088-94-9
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd |
-
- 5(6)-Carboxyfluorescein
72088-94-9
- US $30.00 / kg
- 98%
- hebei hongtan Biotechnology Co., Ltd
-
- 5(6)-Carboxyfluorescein
72088-94-9
- US $29.00 / mg
- 98.85%
- TargetMol Chemicals Inc.
-
- 5(6)-Carboxyfluorescein
72088-94-9
- US $0.00-0.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd