ChemicalBook >> CAS DataBase List >>NVP-BGT226
NVP-BGT226
- CAS No.
- 1245537-68-1
- Chemical Name:
- NVP-BGT226
- Synonyms
- CS-382;BGT226;NVP-BGT226;BGT-226 maleate;BGT226 (NVP-BGT226);NVP-BGT226 (BGT226);NVP-BGT226 (maleate);NVP-BGT226 USP/EP/BP;NVP-BGT226 (free base);BGT-226;NVP BGT226 (BGT226)
- CBNumber:
- CB52589704
- Molecular Formula:
- C28H25F3N6O2.C4H4O4
- Molecular Weight:
- 650.6044696
- MDL Number:
- MFCD22124895
- MOL File:
- 1245537-68-1.mol
Last updated:2023-06-08 09:02:51
Melting point | >215°C (dec.) |
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storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
solubility | DMSO (Slightly) |
form | Solid |
color | White to Pale Yellow |
FDA UNII | 4YG62LG876 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
NFPA 704 |
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NVP-BGT226 price More Price(33)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 22142 | NVP-BGT226 ≥98% | 1245537-68-1 | 1mg | $40 | 2024-03-01 | Buy |
Cayman Chemical | 22142 | NVP-BGT226 ≥98% | 1245537-68-1 | 5mg | $146 | 2024-03-01 | Buy |
Cayman Chemical | 22142 | NVP-BGT226 ≥98% | 1245537-68-1 | 10mg | $274 | 2024-03-01 | Buy |
Cayman Chemical | 22142 | NVP-BGT226 ≥98% | 1245537-68-1 | 25mg | $632 | 2024-03-01 | Buy |
TRC | B367500 | BGT226 | 1245537-68-1 | 5mg | $250 | 2021-12-16 | Buy |
NVP-BGT226 Chemical Properties,Uses,Production
Uses
BGT 226 is a novel phosphatidyl inositol-3 kinase/mammalian target of rapamycin (PI3K/mTOR ) dual inhibitor which has shown to be effective with gefitinib in epidermal growth factor receptor (EGFR) inhibitor-sensitive non-small cell lung cancer (NSCLC) therapy.
Definition
ChEBI: BGT226 is the maleate salt of 8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one. A dual PI3K/mTOR inhibitor. It has a role as an antineoplastic agent, a mTOR inhibitor and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It contains a BGT226(1+).
target
PI3Kα
NVP-BGT226 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 117)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 24330 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
View Lastest Price from NVP-BGT226 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2019-07-06 | 1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt
1245537-68-1
|
US $7.00 / KG | 1KG | 99% | 200KG | Career Henan Chemical Co |
-
- 1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt
1245537-68-1
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
8-(6-methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one Maleic acid
BGT-226 maleate
BGT226 (NVP-BGT226)
BGT226 (NVP-BGT226);NVP-BGT226
8-(6-Methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1H-imidazo
1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl)-8-(6-methoxypyridin-3-yl)-3-methyl-1H-imidazo[4,5-c]quinolin-2(3H)-one maleic acid salt
BGT226
NVP-BGT226
NVP-BGT226 (BGT226)
CS-382
BGT-226;NVP BGT226 (BGT226)
BGT-226 (Maleic Acid Salt)
BGT226 maleate (NVP-BGT226 maleate)
NVP-BGT226 (maleate)
(Z)-but-2-enedioic acid,8-(6-methoxypyridin-3-yl)-3-methyl-1-[4-piperazin-1-yl-3-(trifluoromethyl)phenyl]imidazo[4,5-c]quinolin-2-one
NVP-BGT226 (free base)
NVP-BGT226 USP/EP/BP
8-(6-Methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one maleate
BGT226 (NVP-BGT226) maleate
1245537-68-1
C32H29F3N6O6
C28H25F3N6O2C4H4O4
Akt
mTOR
PI3K
PI3K/Akt/mTOR
Inhibitors