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N-Deboc-Docetaxel

CAS No.
133524-69-3
Chemical Name:
N-Deboc-Docetaxel
Synonyms
N-Deboc-Docetaxel;N-DesBoc Docetaxel;Docetaxel Impurity 40;N-Debenzoyl-10-deacetylpaclitaxel;10-Desacetyl-N-debenzoylpaclitaxel;N-De(tert-butoxycarbonyl)-10-deacetyldocetaxel;(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-ylbenzoate;Docetaxel impurity 3/N-DesBoc Docetaxel/10-Desacetyl-N-debenzoylpaclitaxel/(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12;Benzenepropanoic acid, β-amino-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
CBNumber:
CB52630088
Molecular Formula:
C38H45NO12
Molecular Weight:
707.76
MDL Number:
MFCD30182048
MOL File:
133524-69-3.mol
MSDS File:
SDS
Last updated:2023-05-04 15:13:54

N-Deboc-Docetaxel Properties

Melting point >150°C (dec.)
Boiling point 846.0±65.0 °C(Predicted)
Density 1.41±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 10.19±0.45(Predicted)
color White to Off-White
Stability Hygroscopic
FDA UNII EG6AN1S5YT

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501

N-Deboc-Docetaxel price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D289235 N-DesBocDocetaxel 133524-69-3 5mg $140 2021-12-16 Buy
TRC D289235 N-DesBocDocetaxel 133524-69-3 50mg $1110 2021-12-16 Buy
BroadPharm BP-23249 De-Boc-Docetaxel 95% 133524-69-3 100mg $850 2021-12-16 Buy
Product number Packaging Price Buy
D289235 5mg $140 Buy
D289235 50mg $1110 Buy
BP-23249 100mg $850 Buy

N-Deboc-Docetaxel Chemical Properties,Uses,Production

Uses

N-DesBoc Docetaxel is an impurity in the synthesis of Docetaxel (D494420), a semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic.

N-Deboc-Docetaxel Preparation Products And Raw materials

Raw materials

Preparation Products

N-Deboc-Docetaxel Suppliers

Global( 46)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10319 58
HONG KONG IPURE BIOLOGY CO.,LIMITED
86 18062405514 18062405514 ada@ipurechemical.com CHINA 3461 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11922 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chembest Research Laboratories Limited +86-21-20908456 sales@BioChemBest.com China 6005 61
XiaoGan ShenYuan ChemPharm co,ltd 15527768850 1791901229@qq.com China 8843 52
Cato Research Chemicals Inc. 020-81960175 min.he@cato-chem.com China 1955 55
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 18042 56
N-Deboc-Docetaxel N-DesBoc Docetaxel 10-Desacetyl-N-debenzoylpaclitaxel N-De(tert-butoxycarbonyl)-10-deacetyldocetaxel N-Debenzoyl-10-deacetylpaclitaxel Docetaxel impurity 3/N-DesBoc Docetaxel/10-Desacetyl-N-debenzoylpaclitaxel/(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12 Docetaxel Impurity 40 Benzenepropanoic acid, β-amino-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)- (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-ylbenzoate 133524-69-3 C38H45NO12