ChemicalBook >> CAS DataBase List >>Scopoletin
Scopoletin
- CAS No.
- 92-61-5
- Chemical Name:
- Scopoletin
- Synonyms
- Scopoletol;6-Methoxy-7-hydroxycoumarin;7-HYDROXY-6-METHOXY-2H-CHROMEN-2-ONE;6-METHOXYCOUMARIN;6-Methylesculetin;7-HYDROXY-6-METHOXY-2H-1-BENZOPYRAN-2-ONE;Baogongteng B;GELSEMINIC ACID;CHRYSATROPIC ACID;7-HYDROXY-5-METHOXYCOUMARIN
- CBNumber:
- CB5265273
- Molecular Formula:
- C10H8O4
- Molecular Weight:
- 192.17
- MDL Number:
- MFCD00006872
- MOL File:
- 92-61-5.mol
- MSDS File:
- SDS
Last updated:2024-12-18 14:08:52
| Melting point | 203-205 °C (lit.) |
|---|---|
| Boiling point | 288.14°C (rough estimate) |
| Density | 1.2932 (rough estimate) |
| refractive index | 1.5430 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sightly, Heated), Ethyl Acetate (Slightly, Heated), Methanol (Slightly, Heated) |
| pka | 7.91±0.20(Predicted) |
| form | Crystalline Powder |
| color | Beige |
| Water Solubility | Slightly soluble |
| Merck | 14,8408 |
| BRN | 156296 |
| InChIKey | RODXRVNMMDRFIK-UHFFFAOYSA-N |
| LogP | 1.280 (est) |
| CAS DataBase Reference | 92-61-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | KLF1HS0SXJ |
| NIST Chemistry Reference | 7-Hydroxy-6-methoxy-2h-1-benzopyran-2-one(92-61-5) |
| EPA Substance Registry System | Scopoletin (92-61-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | GN6930000 | |||||||||
| HS Code | 29322090 | |||||||||
| NFPA 704 |
|
Scopoletin price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89516 | Scopoletin phyproof? Reference Substance | 92-61-5 | 50MG | $407 | 2024-03-01 | Buy |
| Sigma-Aldrich | 38332 | Scopoletin analytical standard | 92-61-5 | 10mg | $132 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1610090 | Scopoletin United States Pharmacopeia (USP) Reference Standard | 92-61-5 | 20mg | $229.8 | 2024-03-01 | Buy |
| TCI Chemical | S0367 | Scopoletin >98.0%(HPLC)(T) | 92-61-5 | 100mg | $107 | 2024-03-01 | Buy |
| TCI Chemical | S0367 | Scopoletin >98.0%(HPLC)(T) | 92-61-5 | 1g | $649 | 2024-03-01 | Buy |
Scopoletin Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Uses
Scopoletin is the aglucone of Scopolin. Used for cosmetics, topical formulations, and foods. Dyes and metabolites.
Definition
ChEBI: A hydroxycoumarin that is umbelliferone bearing a methoxy substituent at position 6.
benefits
Scopoletin is a coumarin synthesized by diverse medicinal and edible plants, which plays a vital role as a therapeutic and chemopreventive agent in the treatment of a variety of diseases. Scopoletin is indicated to have antimicrobial, anticancer, anti-inflammation, anti-angiogenesis, anti-oxidation, antidiabetic, antihypertensive, hepatoprotective, and neuroprotective properties and immunomodulatory effects in both in vitro and in vivo experimental trials. In addition, it is an inhibitor of various enzymes, including choline acetyltransferase, acetylcholinesterase, and monoamine oxidase.
Synthesis Reference(s)
The Journal of Organic Chemistry, 27, p. 3083, 1962 DOI: 10.1021/jo01056a023
General Description
Scopoletin is a coumarin compound and pharmacologically active chemical that is found in various plant species.
Biochem/physiol Actions
Scopoletin significantly increases activity of lipoprotein lipase in adipocytes by promoting transcription of the LPL gene. It also partially reverses inhibition of LPL by TNF-α.
Purification Methods
Crystallise it from water, acetic acid or *C6H6/MeOH. It is dimorphic with a second m at 193-195o. It sublimes at 120-130o/12mm. [Beilstein 18 H 99, 18 I 348, 18 II 68, 18 III/IV 1323, 18/3 V 203.]
Scopoletin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 330)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
View Lastest Price from Scopoletin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | Scopoletin
92-61-5
|
US $30.00-61.00 / mg | 99.88% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-05 | Scopoletin
92-61-5
|
US $0.00-0.00 / KG | 5mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2024-04-12 | Scopoletin
92-61-5
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd |
-
- Scopoletin
92-61-5
- US $30.00-61.00 / mg
- 99.88%
- TargetMol Chemicals Inc.
-
- Scopoletin
92-61-5
- US $0.00-0.00 / KG
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-
- Scopoletin
92-61-5
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
92-61-5(Scopoletin)Related Search:
ESCULETIN-6-METHYL ETHER
B-METHYLESCULETIN
SCOPOLETIN
MURRAYETIN
AKOS 214-14
SCOPOLETIN 98.0+% T
NSC 405647
SCOPOLETIN (7-HYDROXY-6-METHOXYCOUMARIN)
6-Methoxyumbelliferone, 7-Hydroxy-5-methoxycoumarin, 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one, Chrysatropic acid, Esculetin-6-methyl ether, Gelseminic acid
Scopoletin，Escopoletin，Chrysatropic acid，Gelseminic acid，6-Methoxyumbelliferone
Scopoletin ,98%
7-hydroxy-6-methoxy-chromen-2-one
7-hydroxy-6-methoxychromen-2-one
Scopoletin,95%
Gelseminic ac
2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy-
Scopoletine
6-METHOXYUMBELLIFERONE
Scopoletin,6-Methoxyumbelliferone, 7-Hydroxy-5-methoxycoumarin, 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one, Chrysatropic acid, Esculetin-6-methyl ether, Gelseminic acid
Scopoletin (20 mg)
7-Hydroxy-6-methoxy-2H-chromen-2-one, 6-Methoxyumbelliferone, Scopoletin
6-Methoxyumbelliferone, 7-Hydroxy-5-methoxycoumarin
GelseMinic acid, Chrysatropic acid, 6-Methylesculetin
Esculetin-6-Methyl ester
Scopoletin, 95% 50MG
Esculetin-6-methyl Ether
7-Hydroxy-6-methoxycoumarin
β-Methylaesculetin
Scopoletin
6-Methoxyumbelliferone
2H-1-
2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy- (9CI)
7-hydroxy-6-methoxy-2-chromenone
6-O-Methylesculetin
7-hydroxy-6-methoxy-2h-1-benzopyran-2-on
7-hydroxy-6-methoxy-coumari
beta-Methylesculetin
Buxuletin
Coumarin, 7-hydroxy-6-methoxy-
Escopoletin
Scopoletin extrapure, 99%
Scopolitine
7-Hydroxy-6-methoxycoumarin (Scopoletin)
Scopolitine ( synthitic)
Scopoletin >
Scopoletin (Gelseminic acid
Scopoletin, 98%, from Morus alba L.
7-hydroxy-6-methoxy-1-benzopyran-2-one
7-HYDROXY-5-METHOXYCOUMARIN
7-HYDROXY-6-METHOXY-2H-1-BENZOPYRAN-2-ONE
7-HYDROXY-6-METHOXY-2H-CHROMEN-2-ONE
6-METHOXYCOUMARIN
7-HYDROXY-6-METHOXYCOUMARIN
CHRYSATROPIC ACID
GELSEMINIC ACID
6-Methoxy-7-hydroxycoumarin
6-Methylesculetin
Scopoletol
Baogongteng B
Scopolamine lactone