ChemicalBook >> CAS DataBase List >>D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)-

D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)-

D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- structure

CAS No.: 160709-02-4

Chemical Name:: D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)-

Synonyms: [5-(2,4difluoro- phenyl)-5-[1,2,4] triazole-1yl-methyltetrahydrofuran-3-yl]-Methanol;3R, 5R-[5-(2,4-Difluoro-phenyl)-5-[1,2,4]triazol-1-ylmethyl-tetrahydro-furan-3-yl]-methanol;((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methanol;(-)-(5R-cis)-5-(2,4-Difluoro-phenyl)-5-[(1H-1,2,4-triazole-1-yl)methyl]-tetrahydro-3-furanmethanol;2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxymethyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol;D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)-;2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxymethyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol (ACI)

CBNumber:: CB52680700

Molecular Formula:: C14H15F2N3O2

Molecular Weight:: 295.28

MDL Number:

MOL File:: 160709-02-4.mol

MSDS File:: SDS

Last updated:2024-07-10 17:45:06

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D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- Properties

Melting point	>69°C (dec.)
Boiling point	457.6±55.0 °C(Predicted)
Density	1.42±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	14.81±0.10(Predicted)
form	Solid
color	White to Off-White
FDA UNII	F6PWB58JT6

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A658770	2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxymethyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol	160709-02-4	500mg	$55	2021-12-16	Buy
Medical Isotopes, Inc.	38726	2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxymethyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol	160709-02-4	500mg	$585	2021-12-16	Buy
Medical Isotopes, Inc.	38726	2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxymethyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol	160709-02-4	25g	$2475	2021-12-16	Buy
Crysdot	CD70001991	((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methanol 95+%	160709-02-4	10g	$878	2021-12-16	Buy
Alichem	160709024	((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methanol	160709-02-4	5g	$333.3	2021-12-16	Buy

Product number	Packaging	Price	Buy
A658770	500mg	$55	Buy
38726	500mg	$585	Buy
38726	25g	$2475	Buy
CD70001991	10g	$878	Buy
160709024	5g	$333.3	Buy

D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- Chemical Properties,Uses,Production

Uses

2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxymethyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol is building block to synthesize key intermediates towards synthesis of highly active azole antifungals Sch 51048, Sch 56592 and Sch 45012. It is also an impurity/intermediate for posaconazole (P689600).

D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- synthesis

Synthesis of D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- from Posaconazole Impurity 24

D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- Preparation Products And Raw materials

Raw materials

2-Oxazolidinone, 3-[4-(2,4-difluorophenyl)-1-oxo-4-pentenyl]-4-(1-methylethyl)-, (S)- (9CI) Benzenebutanoyl chloride, 2,4-difluoro-γ-methylene- 2-Oxazolidinone, 3-[4-(2,4-difluorophenyl)-1-oxo-2-[(phenylmethoxy)methyl]-4-pentenyl]-4-(1-methylethyl)-, [S-(R*,S*)]- (9CI) 3-Furanmethanol, 5-(2,4-difluorophenyl)tetrahydro-5-(iodomethyl)-, acetate, (2R-cis)- (9CI) Propanoic acid, 2-methyl-, [(3S)-5-(2,4-difluorophenyl)tetrahydro-5-(iodomethyl)-3-furanyl]methyl ester

Posaconazole Impurity 33 Posaconazole Impurity 24 1-(((2R,4R)-4-((Benzyloxy)methyl)-2-(2,4-difluorophenyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole (S)-4-(2,4-difluorophenyl)-2-(hydroxymethyl)pent-4-en-1-ylisobutyrate 1,2,4-Triazole

1,2,4-Triazolylsodium

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Preparation Products

O-Benzyl Posaconazole

D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- Suppliers

Global( 70)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ShenZhen H&D Pharmaceutical Technology Co., LTD	+8618627948422	sale@hdimpurity.com	China	3389	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Hangzhou FandaChem Co.,Ltd.	+8615858145714	FandaChem@Gmail.com	China	9116	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Chemsigma International Co., Ltd.	+86-18136843612 +86-19951791336	info@chemsigma.com	China	1369	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24727	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11922	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58

Supplier	Advantage
ShenZhen H&D Pharmaceutical Technology Co., LTD	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Chemsigma International Co., Ltd.	58
LEAP CHEM CO., LTD.	58
China National Standard Pharmaceutical Corporation Limited	58
Aladdin Scientific	58

View Lastest Price from D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-09-20	Posaconazole Impurity 20	US $0.00-0.00 / mg	10mg	98%	500mg	ShenZhen H&D Pharmaceutical Technology Co., LTD
2024-09-20	Posaconazole Impurity 20 160709-02-4	US $0.00-0.00 / mg	10mg	98%	500mg	ShenZhen H&D Pharmaceutical Technology Co., LTD
2019-12-26	D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- 160709-02-4	US $9.80 / KG	1g	≥99%	100kg	Career Henan Chemical Co

Posaconazole Impurity 20
US $0.00-0.00 / mg
98%
ShenZhen H&D Pharmaceutical Technology Co., LTD

Posaconazole Impurity 20
160709-02-4
US $0.00-0.00 / mg
98%
ShenZhen H&D Pharmaceutical Technology Co., LTD

D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)-
160709-02-4
US $9.80 / KG
≥99%
Career Henan Chemical Co

160709-02-4(D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)-)Related Search:

Posaconazole (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester 1-[1-(Bromomethyl)ethenyl]-2,4-difluoro-benzene Posaconazole Impurity 49 Posaconazole Impurity 44

Posaconazole Impurity 17 1-((2S,3R)-2-(benzyloxy)pentan-3-yl)-N-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)hydrazine-1-carboxamide Posaconazole Diastereoisomer 11 Posaconazole DiastereoisoMer interMediate 5 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one

Posaconazole DiastereoisoMer 2 Posaconazole inter-8 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one Posaconazole iMpurity 1,3-PROPANEDIOL, 2-[2-(2,4-DIFLUOROPHENYL)-2-PROPEN-1-YL]-

Posaconazole Diastereoisomer 12 Posaconazole-d4 Posaconazole DiastereoisoMer interMediate 2

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D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- [5-(2,4difluoro- phenyl)-5-[1,2,4] triazole-1yl-methyltetrahydrofuran-3-yl]-Methanol 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxymethyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol 3R, 5R-[5-(2,4-Difluoro-phenyl)-5-[1,2,4]triazol-1-ylmethyl-tetrahydro-furan-3-yl]-methanol ((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methanol (-)-(5R-cis)-5-(2,4-Difluoro-phenyl)-5-[(1H-1,2,4-triazole-1-yl)methyl]-tetrahydro-3-furanmethanol 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxymethyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol (ACI) 160709-02-4