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Nexturastat A

Nexturastat A structure

CAS No.: 1403783-31-2

Chemical Name:: Nexturastat A

Synonyms: CS-1289;Nexturastat A;Nextunastat A;Nexturastat A, >97%;Nexturastat A, >=98%;Nexturastat A (AG-CR1-3901);4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE;4-[[butyl(phenylcarbamoyl)amino]methyl]-N-hydroxybenzamide;4-[[Butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxybenzamide;Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy-

CBNumber:: CB52715657

Molecular Formula:: C19H23N3O3

Molecular Weight:: 341.4

MDL Number:: MFCD28099804

MOL File:: 1403783-31-2.mol

MSDS File:: SDS

Last updated:2024-11-19 23:02:33

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Nexturastat A Properties

Density	1.228±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	insoluble in H2O; ≥16.3 mg/mL in DMSO; ≥9.3 mg/mL in EtOH
form	solid
pka	8.95±0.10(Predicted)
color	White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P280-P305+P351+P338

NFPA 704

	0
2		0

Nexturastat A price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	16874	Nexturastat A ≥95%	1403783-31-2	500μg	$62	2024-03-01	Buy
Cayman Chemical	16874	Nexturastat A ≥95%	1403783-31-2	1mg	$109	2024-03-01	Buy
Cayman Chemical	16874	Nexturastat A ≥95%	1403783-31-2	5mg	$477	2024-03-01	Buy
Cayman Chemical	16874	Nexturastat A ≥95%	1403783-31-2	10mg	$834	2024-03-01	Buy
TRC	N391500	NexturastatA	1403783-31-2	25mg	$1760	2021-12-16	Buy

Product number	Packaging	Price	Buy
16874	500μg	$62	Buy
16874	1mg	$109	Buy
16874	5mg	$477	Buy
16874	10mg	$834	Buy
N391500	25mg	$1760	Buy

Nexturastat A Chemical Properties,Uses,Production

Uses

Nexturastat A is a potent and selective histone deacetylase 6 (HDAC6) inhibitor that shows potential antiproliferative effects against melanoma cells.

Biological Activity

nexturastat a is a selective inhibitor of histone deacetylase 6 (hdac6) with ic50 value of 5.2 nm [1].nexturastat a is a hdac inhibitor. it was developed by structural modification of aryl urea hdacis. the inhibitory activity of nexturastat a is most potent against hdac6 with ic50 value of 5.2 nm. besides that, nexturastat a also shows inhibition of other hdacs with ic50 values of 3.02, 6.92, 6.68, 9.39, 11.7, 4.46, 0.954, 6.72, 7.57 and 5.14 μm for hdac1, 2, 3, 4, 5, 7, 8, 9, 10 and 11, respectively. nexturastat a has been shown to suppress cell proliferation and promote apoptosis in b16 murine melanoma cells [1, 2].

target

HDAC6

References

[1] kalin j h, bergman j a. development and therapeutic implications of selective histone deacetylase 6 inhibitors. journal of medicinal chemistry, 2013, 56(16): 6297-6313.
[2] zhang l, han y, jiang q, et al. trend of histone deacetylase inhibitors in cancer therapy: isoform selectivity or multitargeted strategy. medicinal research reviews, 2014.

Nexturastat A Preparation Products And Raw materials

Raw materials

Preparation Products

Nexturastat A Suppliers

Global( 96)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29882	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6312	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24727	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9984	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
LEAP CHEM CO., LTD.	58
Coresyn Pharmatech Co., Ltd.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aladdin Scientific	58

View Lastest Price from Nexturastat A manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	Nexturastat A 1403783-31-2	US $63.00-117.00 / mg		99.57%	10g	TargetMol Chemicals Inc.
	2019-09-05	4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE 1403783-31-2	US $1.00 / ASSAYS	1ASSAYS	98%	10kg	Career Henan Chemical Co

Nexturastat A
1403783-31-2
US $63.00-117.00 / mg
99.57%
TargetMol Chemicals Inc.

4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE
1403783-31-2
US $1.00 / ASSAYS
98%
Career Henan Chemical Co

Nexturastat A Spectrum

Nexturastat A(1403783-31-2)¹HNMR

1403783-31-2(Nexturastat A)Related Search:

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Entinostat

1of2

Nexturastat A, >=98% 4-[[Butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxybenzamide Nexturastat A 4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy- Nexturastat A 4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE Nexturastat A Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy- 4-[[butyl(phenylcarbamoyl)amino]methyl]-N-hydroxybenzamide CS-1289 Nexturastat A, >97% Nextunastat A Nexturastat A (AG-CR1-3901) 1403783-31-2 Inhibitors