1,2-dioctanoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (aMMoniuM salt)
- CAS No.
- 852043-37-9
- Chemical Name:
- 1,2-dioctanoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (aMMoniuM salt)
- Synonyms
- 5)P2;08:0 PI(4;08:0 PI(4,5)P2;1,2-dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-4',5'-bisphosphate) (ammonium salt);1,2-dioctanoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (aMMoniuM salt);1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHO-(1'-MYO-INOSITOL-4',5'-BISPHOSPHATE) (AMMONIUM SALT);08:0 PI(4;5)P2;(2R)-3-[hydroxy-[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-diphosphonooxycyclohexyl]oxyphosphoryl]oxy-2-octanoyloxypropyl] octanoate
- CBNumber:
- CB52720741
- Molecular Formula:
- C25H52NO19P3
- Molecular Weight:
- 763.6
- MDL Number:
- MFCD22416576
- MOL File:
- 852043-37-9.mol
- MSDS File:
- SDS
1,2-dioctanoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (aMMoniuM salt) Chemical Properties,Uses,Production
Uses
Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states.
Uses
08:0 PI(4,5)P2 is suitable for use to identify its binding site in transient?receptor potential vanilloid 4 (TRPV4?N) terminus. It has been used in in vitro binding assay to determine the binding of G-protein coupled receptor kinases (GRKs) and β2-adrenergic receptor (β2AR).
General Description
Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT. The dioctanoyl derivative of PI(4,5)P2 is more water soluble than its long chain counterparts.
1,2-dioctanoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (aMMoniuM salt) Preparation Products And Raw materials
Raw materials
Preparation Products
1,2-dioctanoyl-sn-glycero-3-phospho-(1'-Myo-inositol-4',5'-bisphosphate) (aMMoniuM salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52925 | 58 |
| Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17687 | 55 |
| Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14603 | 60 |
| Beijing Qinling Pharmaceutical Co., Ltd. | 010-61241352 18901327973 | sales@qlmed.com | China | 4365 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 15102117276 19921389125 | tech@zzbioco.com | China | 12065 | 58 |
| Supplier | Advantage |
|---|---|
| Creative Enzymes | 58 |
| Aladdin Scientific | 58 |
| Codow Chemical Co.,Ltd. | 55 |
| Chengdu Dianchun Technology Co., Ltd | 60 |
| Beijing Qinling Pharmaceutical Co., Ltd. | 58 |
| SHANGHAI ZZBIO CO., LTD. | 58 |