ChemicalBook >> CAS DataBase List >>2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid
![2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid Structure](CAS/20150408/GIF/1449779-49-0.gif)
- CAS No.
- 1449779-49-0
- Chemical Name:
- 2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid
- Synonyms
- CS-2804;CS-2654;DGAT1-IN-1;DGAT1 inhibitor 1;DGAT1-IN-1, 10 mM in DMSO;2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid;rel-2-((1r,4r)-4-(4-(2-((4-(Trifluoromethoxy)benzyl)carbamoyl)imidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid;2-[(1r,4r)-4-{4-[2-({[4-(trifluoromethoxy)phenyl]methyl}carbamoyl)imidazo[1,2-a]pyridin-6-yl]phenyl}cyclohexyl]acetic acid;Cyclohexaneacetic acid, 4-[4-[2-[[[[4-(trifluoromethoxy)phenyl]methyl]amino]carbonyl]imidazo[1,2-a]pyridin-6-yl]phenyl]-, trans-;Diacylglycerol acyltransferase,inhibit,Acyltransferase,mono- acylglycerol acyltransferase,Inhibitor,DGAT1 IN 1,Diglyceride acyltransferase,acyl-CoA:cholesterol acyltransferase,DGAT-1-IN-1,DGAT1IN1
- CBNumber:
- CB52722376
- Molecular Formula:
- C30H28F3N3O4
- Molecular Weight:
- 551.56
- MDL Number:
- MFCD28167832
- MOL File:
- 1449779-49-0.mol
Last updated:2025-04-17 18:22:24
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid Properties
| Density | 1.36±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMSO : 20 mg/mL (36.26 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
| form | Powder |
| pka | 4.72±0.10(Predicted) |
| color | White to off-white |
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-3431 | DGAT1-IN-1 95.14% | 1449779-49-0 | 5mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-3431 | DGAT1-IN-1 95.14% | 1449779-49-0 | 10mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-3431 | DGAT1-IN-1 95.14% | 1449779-49-0 | 50mg | $750 | 2021-12-16 | Buy |
| ChemScene | CS-3431 | DGAT1-IN-1 95.14% | 1449779-49-0 | 100mg | $1250 | 2021-12-16 | Buy |
| Chemenu | CM322056 | 2-(trans-4-(4-(2-((4-(Trifluoromethoxy)benzyl)carbamoyl)imidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)aceticacid 98% | 1449779-49-0 | 100mg | $284 | 2021-12-16 | Buy |
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid Chemical Properties,Uses,Production
Uses
DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1). IC50 value: < 10 nM Target: DGAT1 inhibitor Imidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparation By Kim, Dooseop; Bok, Juhan; Shin, Sunmi From PCT Int. Appl. (2013), WO 2013119040 A1 20130815.
References
[1] Compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme , Patent: WO 2013119040 A1
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid Suppliers
Global( 40)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7552 | 61 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4601 | 55 | |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9923 | 65 |
| Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 | 505721671@qq.com | China | 3866 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4660 | 60 |
View Lastest Price from 2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | DGAT1-IN-1
1449779-49-0
|
US $56.00-122.00 / mg | 99.15% | 10g | TargetMol Chemicals Inc. |
-
- DGAT1-IN-1
1449779-49-0
- US $56.00-122.00 / mg
- 99.15%
- TargetMol Chemicals Inc.
2-((1r,4r)-4-(4-(2-((4-(trifluoroMethoxy)benzyl)carbaMoyl)iMidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid
DGAT1-IN-1
CS-2654
CS-2804
DGAT1 inhibitor 1
Cyclohexaneacetic acid, 4-[4-[2-[[[[4-(trifluoromethoxy)phenyl]methyl]amino]carbonyl]imidazo[1,2-a]pyridin-6-yl]phenyl]-, trans-
Diacylglycerol acyltransferase,inhibit,Acyltransferase,mono- acylglycerol acyltransferase,Inhibitor,DGAT1 IN 1,Diglyceride acyltransferase,acyl-CoA:cholesterol acyltransferase,DGAT-1-IN-1,DGAT1IN1
rel-2-((1r,4r)-4-(4-(2-((4-(Trifluoromethoxy)benzyl)carbamoyl)imidazo[1,2-a]pyridin-6-yl)phenyl)cyclohexyl)acetic acid
2-[(1r,4r)-4-{4-[2-({[4-(trifluoromethoxy)phenyl]methyl}carbamoyl)imidazo[1,2-a]pyridin-6-yl]phenyl}cyclohexyl]acetic acid
DGAT1-IN-1, 10 mM in DMSO
1449779-49-0