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Intermediate of Rolapitant

Intermediate of Rolapitant Structure
Intermediate of Rolapitant structure
CAS No.
205654-80-4
Chemical Name:
Intermediate of Rolapitant
Synonyms
Intermediate of Rolapitant;(2R,4S)-benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate;Benzyl (2r,4s)-5-oxo-2,4-diphenyloxazolidine-3-carboxylate;3-FLUORO-2-NITROPHENOL (2R)-5-OXOPYRROLIDINE-2-CARBOXYLIC ACID;3-Oxazolidinecarboxylic acid,5-oxo-2,4-diphenyl-,phenylmethyl ester,(2R,4S)-
CBNumber:
CB52743016
Molecular Formula:
C23H19NO4
Molecular Weight:
373.4
MDL Number:
MFCD30718663
MOL File:
205654-80-4.mol
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Intermediate of Rolapitant Properties

Boiling point 591.6±50.0 °C(Predicted)
Density 1.270±0.06 g/cm3(Predicted)
pka -3.96±0.60(Predicted)

Intermediate of Rolapitant price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B287516 (2R,4S)-Benzyl5-oxo-2,4-diphenyloxazolidine-3-carboxylate 205654-80-4 2.5g $990 2021-12-16 Buy
Product number Packaging Price Buy
B287516 2.5g $990 Buy

Intermediate of Rolapitant Chemical Properties,Uses,Production

Uses

(2R,4S)-Benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate is an intermediate in the preparation of Rolapitant (R639800). Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced nausea and vomiting.

Intermediate of Rolapitant Preparation Products And Raw materials

Raw materials

Preparation Products

Intermediate of Rolapitant Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
AFINE CHEMICALS LIMITED 		+86-0571-85134551 info@afinechem.com China 15395 58
Shanghai QianYan Bio-technology Co., Ltd 02781293128 orders@biochemsafebuy.com China 9934 55
Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd +86-021-50929289 86186163093 sales@ypptech.com.cn China 341 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20035 58
Shaanxi Didu New Material Co., Ltd 029-63373950 15353716720 1052@dideu.com China 10011 58
Shanghai Easy CDMO Co.,Ltd 021-61734564 August@easycdmo.com China 10010 58
Shaanxi Henghan New Materials Co., Ltd 15619311539 907967238@qq.com China 2647 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 025-66061636 18013972705 qqyang@aikonchem.com China 5067 58
Supplier Advantage
AFINE CHEMICALS LIMITED 		58
Shanghai QianYan Bio-technology Co., Ltd 55
Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd 58
Suzhou Meishi Biotechnology Co., Ltd. 58
Shaanxi Didu New Material Co., Ltd 58
Shanghai Easy CDMO Co.,Ltd 58
Shaanxi Henghan New Materials Co., Ltd 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 58
Intermediate of Rolapitant (2R,4S)-benzyl 5-oxo-2,4-diphenyloxazolidine-3-carboxylate 3-Oxazolidinecarboxylic acid,5-oxo-2,4-diphenyl-,phenylmethyl ester,(2R,4S)- 3-FLUORO-2-NITROPHENOL (2R)-5-OXOPYRROLIDINE-2-CARBOXYLIC ACID Benzyl (2r,4s)-5-oxo-2,4-diphenyloxazolidine-3-carboxylate 205654-80-4