Chinese Japanese Germany Korea

3-Cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-benzenesulfonamide

3-Cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-benzenesulfonamide Structure
3-Cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-benzenesulfonamide structure
CAS No.
1235397-05-3
Chemical Name:
3-Cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-benzenesulfonamide
Synonyms
PF4856264;PF 4856264;PF-4856264;PF-04856264;PF 04856264,PF04856264;PF-04856264 >=98% (HPLC);3-Cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-benzenesulfonamide;Benzenesulfonamide, 3-cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-;3-cyano-4-[2-(2-methylpyrazol-3-yl)phenoxy]-N-(1,3-thiazol-2-yl)benzenesulfonamide;3-CYANO-4-(2-(1-METHYL-1H-PYRAZOL-5-YL) PHENOXY)-N-(THIAZOL-2-YL) BENZENESULFONAMIDE
CBNumber:
CB52750715
Molecular Formula:
C20H15N5O3S2
Molecular Weight:
437.49
MDL Number:
MFCD28124397
MOL File:
1235397-05-3.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06
Request For Quotation

3-Cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-benzenesulfonamide Properties

Boiling point 635.0±65.0 °C(Predicted)
Density 1.44±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble10mg/mL, clear
form powder
pka 5.68±0.10(Predicted)
color white to light brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3

3-Cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-benzenesulfonamide price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML1061 PF-04856264 ≥98% (HPLC) 1235397-05-3 5mg $157 2024-03-01 Buy
Sigma-Aldrich SML1061 PF-04856264 ≥98% (HPLC) 1235397-05-3 25mg $624 2024-03-01 Buy
ChemScene CS-0012528 PF-04856264 ≥99.0% 1235397-05-3 5mg $504 2021-12-16 Buy
Chemenu CM331018 3-cyano-4-[2-(2-methylpyrazol-3-yl)phenoxy]-N-(1,3-thiazol-2-yl)benzenesulfonamide 95%+ 1235397-05-3 100mg $582 2021-12-16 Buy
Chemenu CM331018 3-cyano-4-[2-(2-methylpyrazol-3-yl)phenoxy]-N-(1,3-thiazol-2-yl)benzenesulfonamide 95%+ 1235397-05-3 250mg $965 2021-12-16 Buy
Product number Packaging Price Buy
SML1061 5mg $157 Buy
SML1061 25mg $624 Buy
CS-0012528 5mg $504 Buy
CM331018 100mg $582 Buy
CM331018 250mg $965 Buy

3-Cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-benzenesulfonamide Chemical Properties,Uses,Production

Biochem/physiol Actions

PF-04856264 is a potent, selective inhibitor of the human Nav1.7 voltage gated sodium channel (IC50 = 28 nM). PF-04856264 blocks mouse Nav1.7 (IC50 = 131 nM) but has low potency against the rat Nav1.7 channel (IC50 = 4.2 mM).

3-Cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-benzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

3-Cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-benzenesulfonamide Suppliers

Global( 20)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10312 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Jinan elephant international trading co., LTD 13006575422@163.com China 6357 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29786 68
MQ (shanghai) Pharmaceuticals Co., Ltd. 13761635123 1014988033@qq.com China 4977 55
Jinan Yaoyan Pharmaceutical Co., Ltd. jnyaoyan@163.com China 3069 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19105 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9412 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Supplier Advantage
Shenzhen Nexconn Pharmatechs Ltd 		58
TargetMol Chemicals Inc. 		58
Sigma-Aldrich 80
Jinan elephant international trading co., LTD 58
Beijing Solarbio Science & Tecnology Co., Ltd. 68
MQ (shanghai) Pharmaceuticals Co., Ltd. 55
Jinan Yaoyan Pharmaceutical Co., Ltd. 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. 58
DC Chemicals 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
3-Cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl-benzenesulfonamide PF-04856264 3-cyano-4-[2-(2-methylpyrazol-3-yl)phenoxy]-N-(1,3-thiazol-2-yl)benzenesulfonamide 3-CYANO-4-(2-(1-METHYL-1H-PYRAZOL-5-YL) PHENOXY)-N-(THIAZOL-2-YL) BENZENESULFONAMIDE PF-04856264 >=98% (HPLC) PF 4856264 PF4856264 PF-4856264 PF 04856264,PF04856264 Benzenesulfonamide, 3-cyano-4-[2-(1-methyl-1H-pyrazol-5-yl)phenoxy]-N-2-thiazolyl- 1235397-05-3