ANTI-TYROSINE HYDROXYLASE
- CAS No.
- Chemical Name:
- ANTI-TYROSINE HYDROXYLASE
- Synonyms
- ANTI-TH;ANTI-TH, RAT;ANTI-TYROSINE HYDROXYLASE;Anti-Tyrosine 3-hydroxylase;ANTI-RAT TYROSINE HYDROXYLASE;Anti-Tyrosine 3-monooxygenase;ANTI-TYROSINE HYDROXYLASE, RAT;ANTI-TYROSINE HYDROXYLASE SHEEP PAB;ANTI-TYROSINE HYDROXYLASE MOUSE MAB;ANTI-TYROSINE HYDROXYLASE RABBIT PAB
- CBNumber:
- CB5281039
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00213051
- MOL File:
- Mol file
ANTI-TYROSINE HYDROXYLASE price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | T2928 | Monoclonal Anti-Tyrosine Hydroxylase antibody produced in mouse clone TH-16, ascites fluid | 100μL | $499 | 2024-03-01 | Buy | |
Sigma-Aldrich | T2928 | Monoclonal Anti-Tyrosine Hydroxylase antibody produced in mouse clone TH-16, ascites fluid | 0.2mL | $657 | 2024-03-01 | Buy | |
Sigma-Aldrich | T1299 | Monoclonal Anti-Tyrosine Hydroxylase antibody produced in mouse clone TH-2, ascites fluid | 100μL | $499 | 2024-03-01 | Buy | |
Sigma-Aldrich | T1299 | Monoclonal Anti-Tyrosine Hydroxylase antibody produced in mouse clone TH-2, ascites fluid | 0.2mL | $657 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB4300675 | Anti-Th (Ab-31) antibody produced in rabbit affinity isolated antibody | 100μG | $511 | 2024-03-01 | Buy |
ANTI-TYROSINE HYDROXYLASE Chemical Properties,Uses,Production
Uses
Monoclonal Anti-Tyrosine Hydroxylase antibody produced in mouse has also been used in
- western blotting
- immunofluorescence labelling
- immunohistochemical staining
- enzyme linked immunosorbent assay (ELISA)
- dot blot
- immunoprecipitation
- immunocytochemistry
General Description
Monoclonal Anti-Tyrosine Hydroxylase (mouse IgG1 isotype) is derived from the TH-16 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from immunized BALB/c mice. Tyrosine hydroxylase (TH) exists in four isoforms in humans. They are are TH-1 (M.W. 55,600), TH-2 (4 additional amino acids; M.W. 56,000), TH-3, (27 additional amino acids; M.W. 58,100), and TH-4 (4 plus 27 additional amino acids; 58,500). Only humans express all four isoforms; all other anthropoids express only the TH-1 and TH-2 isoforms.
Biochem/physiol Actions
Tyrosine hydroxylase (TH) catalyzes the first rate limiting step in the biosynthesis of catecholamine neurotransmitter i.e. the conversion of L-tyrosine to L-dopa. Inhibition of TH by L-phenylalanine, might play a crucial role in phenylketonuria and block the synthesis of norepinephrine. Activity of TH can be regulated by phosphorylation. Decreased expression of TH is associated with various neuropsychiatric diseases such as schizophrenia and Parkinson′s disease (PD).
ANTI-TYROSINE HYDROXYLASE Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-TYROSINE HYDROXYLASE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |