ChemicalBook >> CAS DataBase List >>Homoarginine

Homoarginine

CAS No.
156-86-5
Chemical Name:
Homoarginine
Synonyms
C01924;l-lysin;H-HAR-OH;(3βH-HOARG-OH;HOMOARGININE;H-HOMOARG-OH;L-HomoArg-OH;L-HOMOARGININE;H-HOMOARGININE
CBNumber:
CB5298985
Molecular Formula:
C7H16N4O2
Molecular Weight:
188.23
MDL Number:
MFCD00237108
MOL File:
156-86-5.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

Homoarginine Properties

Melting point 207-209 °C
Boiling point 376.3±52.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka 2.52±0.24(Predicted)
color White to off-white
CAS DataBase Reference 156-86-5(CAS DataBase Reference)
FDA UNII JF751CK38I

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501

Homoarginine price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC H585008 Homoarginine 156-86-5 10g $220 2021-12-16 Buy
ChemScene CS-W008385 H-HoArg-OH ≥98.0% 156-86-5 100g $278 2021-12-16 Buy
Chem-Impex 03989 L-Homoarginine ≥ 99% (Assay) 156-86-5 5G $30 2021-12-16 Buy
Activate Scientific AS92343 L-Homoarginine 95% ee 156-86-5 5G $99 2021-12-16 Buy
ChemPep 180132 H-HoArg-OH 156-86-5 5g $142 2021-12-16 Buy
Product number Packaging Price Buy
H585008 10g $220 Buy
CS-W008385 100g $278 Buy
03989 5G $30 Buy
AS92343 5G $99 Buy
180132 5g $142 Buy

Homoarginine Chemical Properties,Uses,Production

Description

Homoarginine and 1-hydroxyhomoarginine were originally detected in significant concentration in the seeds of many Lathyrus species (Bell, 1962a,b; 1963). Homoarginine was isolated from the seeds of L. cicera (Bell, 1962b) and L. sativus (Rao et al., 1963). The hydroxy compound was obtained from the seeds of L. tingitanus (Bell, 1964). The comparative distribution of guanidino compounds in the seeds of two genus of the Papilionoideae, Lathyrus and Vicia, exhibits interesting features (Bell and Tirimanna, 1964). For example, the genus Lathyrus stores predominantly the C7 amino acids homoarginine, y-hydroxyhomoarginine and the related compound lathyrine, while the genus Vicia stores relatively high concentrations of canavanine and of the C6 amino acids arginine and y-hydroxyarginine. Apart from plants, homoarginine was found in small amounts in human body fluids ,. urine (Armstrong, 1967), serum (Matsumoto et al., 1976a) and cerebrospinal fluid (Mori et al., 1981b) and in mammalian brain (Mori et al., 1978, 1979 ). Increased urinary excretion was reported in hyperlysinemia (Armstrong and Robinow, 1967) and citrullinemia (Scott-Emuakpor et al., 19(2).
Homoarginine may be formed in mammals from lysine, by a homologous urea cycle in which arginine is replaced by lysine (Ryan and Wells, 1964; Scott-Emuakpor et al., 19(2). The excretion of homocitrulline and homoarginine in urine following administration of lysine to children supports this theory (Buergi et al., 1966). The biosynthesis of homoarginine has not been examined in plants, but y-hydroxyhomoarginine is synthesized from homoarginine in Lathyrus seeds (Bell, 1964). Subsequently both compounds have been identified as the precursors of the cyclic guanidino derivative, lathyrine, also present in Lathyrus seeds (Bell and Przybylska, 1965). Homoarginine and y-hydroxyhomoarginine probably serve as nitrogen reserves in Lathyrus seeds.
Inhibition of growth by homoarginine has been reported In various microorganisms (Walker, 1955; Rao et al., 1963).
gama-Hydroxyhomoarginine lactone isolated from the seeds of L. tingitanus (Bell, 1964) probably results from the cyclization of the open chain compound under acidic conditions.

Chemical Properties

White to off-white powder

Uses

Homoarginine is an inhibitor of human arginase activity.

Uses

Homoarginine as marker for exogenous protein
Absorption and secretion of free homoarginine in the intestine: when 9 mmol homoarginine were infused into the proximal part of the jejunum, there was a 99.9% disappearance of the free amino acid homoarginine up to the ileum. In addition, following the infusion of 9 mmol homoarginine into the vena jugularis less than 0.2% of the infused homoarginine appeared in the intestine.
We concluded from these data that with the homoarginine method endogenous protein in the chyme of the intestine can be distinguished from the food protein as homoarginine is not incorporated into endogenous secreta and free homo arginine is completely absorbed.

Definition

ChEBI: An L-lysine derivative that is the L-enantiomer of homoarginine.

Homoarginine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 192)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18751 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32956 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2930 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from Homoarginine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Homoarginine pictures 2024-12-13 Homoarginine
156-86-5
US $0.00 / Kg/Drum 1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
H-HoArg-OH pictures 2024-11-19 H-HoArg-OH
156-86-5
US $29.00 / mg 99.74% 10g TargetMol Chemicals Inc.
L-homoarginine pictures 2021-07-02 L-homoarginine
156-86-5
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • Homoarginine pictures
  • Homoarginine
    156-86-5
  • US $0.00 / Kg/Drum
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • H-HoArg-OH pictures
  • H-HoArg-OH
    156-86-5
  • US $29.00 / mg
  • 99.74%
  • TargetMol Chemicals Inc.
  • L-homoarginine pictures
  • L-homoarginine
    156-86-5
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd

Homoarginine Spectrum

l-lysin l-n(sup6)-amidinolysine n(sup6)-(aminoiminomethyl)-l-lysin L-HOMOARGININE L-ALPHA-AMINO-EPSILON-GUANIDINOHEXANOIC ACID H-HOMOARG-OH H-HOARG-OH H-HAR-OH HOMOARGININE (2S)-2-amino-6-(diaminomethylideneamino)hexanoic acid Homo-L-arginine H-HOMOARGININE L-LYSINE, N6-(AMINOIMINOMETHYL)- (S)-2-AMINO-6-GUANIDINOHEXANOIC ACID L-α-Amino-ε-guanidinohexanoic acid N6-Amidino-L-lysine C01924 H-HoMoarg-OH(H-HoMoarginine) L-a-AMino-e-guanidinohexanoic acid L-Homoarginine≥ 99% (Assay) L-HomoArg-OH 1-(1,1,2,2-tetrafluoroethoxy)-4-[2-[4-(1,1,2,2-tetrafluoroethoxy)phenyl]propan-2-yl]benzene Homoarginine USP/EP/BP Homoarginine,97% L-Homo-Arginine-OH Homoarginine reference substance (3β )-olean-12-ene-3,28-diol Valine Impurity 28 156-86-5 Amino Acids Chiral Compound Unusual Amino Acids