Homoarginine
- CAS No.
- 156-86-5
- Chemical Name:
- Homoarginine
- Synonyms
- C01924;l-lysin;H-HAR-OH;(3βH-HOARG-OH;HOMOARGININE;H-HOMOARG-OH;L-HomoArg-OH;L-HOMOARGININE;H-HOMOARGININE
- CBNumber:
- CB5298985
- Molecular Formula:
- C7H16N4O2
- Molecular Weight:
- 188.23
- MDL Number:
- MFCD00237108
- MOL File:
- 156-86-5.mol
- MSDS File:
- SDS
Melting point | 207-209 °C |
---|---|
Boiling point | 376.3±52.0 °C(Predicted) |
Density | 1.39±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | Powder |
pka | 2.52±0.24(Predicted) |
color | White to off-white |
CAS DataBase Reference | 156-86-5(CAS DataBase Reference) |
FDA UNII | JF751CK38I |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H312-H332 |
Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501 |
Homoarginine price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | H585008 | Homoarginine | 156-86-5 | 10g | $220 | 2021-12-16 | Buy |
ChemScene | CS-W008385 | H-HoArg-OH ≥98.0% | 156-86-5 | 100g | $278 | 2021-12-16 | Buy |
Chem-Impex | 03989 | L-Homoarginine ≥ 99% (Assay) | 156-86-5 | 5G | $30 | 2021-12-16 | Buy |
Activate Scientific | AS92343 | L-Homoarginine 95% ee | 156-86-5 | 5G | $99 | 2021-12-16 | Buy |
ChemPep | 180132 | H-HoArg-OH | 156-86-5 | 5g | $142 | 2021-12-16 | Buy |
Homoarginine Chemical Properties,Uses,Production
Description
Homoarginine and 1-hydroxyhomoarginine were originally detected in significant concentration in the seeds of many Lathyrus species (Bell, 1962a,b; 1963). Homoarginine was isolated from the seeds of L. cicera (Bell, 1962b) and L. sativus (Rao et al., 1963). The hydroxy compound was obtained from the seeds of L. tingitanus (Bell, 1964). The comparative distribution of guanidino compounds in the seeds of two genus of the Papilionoideae, Lathyrus and Vicia, exhibits interesting features (Bell and Tirimanna, 1964). For example, the genus Lathyrus stores predominantly the C7 amino acids homoarginine, y-hydroxyhomoarginine and the related compound lathyrine, while the genus Vicia stores relatively high concentrations of canavanine and of the C6 amino acids arginine and y-hydroxyarginine. Apart from plants, homoarginine was found in small amounts in human body fluids ,. urine (Armstrong, 1967), serum (Matsumoto et al., 1976a) and cerebrospinal fluid (Mori et al., 1981b) and in mammalian brain (Mori et al., 1978, 1979 ). Increased urinary excretion was reported in hyperlysinemia (Armstrong and Robinow, 1967) and citrullinemia (Scott-Emuakpor et al., 19(2).
Homoarginine may be formed in mammals from lysine, by a homologous urea cycle in which arginine is replaced by lysine (Ryan and Wells, 1964; Scott-Emuakpor et al., 19(2). The excretion of homocitrulline and homoarginine in urine following administration of lysine to children supports this theory (Buergi et al., 1966). The biosynthesis of homoarginine has not been examined in plants, but y-hydroxyhomoarginine is synthesized from homoarginine in Lathyrus seeds (Bell, 1964). Subsequently both compounds have been identified as the precursors of the cyclic guanidino derivative, lathyrine, also present in Lathyrus seeds (Bell and Przybylska, 1965). Homoarginine and y-hydroxyhomoarginine probably serve as nitrogen reserves in Lathyrus seeds.
Inhibition of growth by homoarginine has been reported In various microorganisms (Walker, 1955; Rao et al., 1963).
gama-Hydroxyhomoarginine lactone isolated from the seeds of L. tingitanus (Bell, 1964) probably results from the cyclization of the open chain compound under acidic conditions.
Chemical Properties
White to off-white powder
Uses
Homoarginine is an inhibitor of human arginase activity.
Uses
Homoarginine as marker for exogenous protein
Absorption and secretion of free homoarginine in the intestine: when 9 mmol homoarginine were infused into the proximal part of the jejunum, there was a 99.9% disappearance of the free amino acid homoarginine up to the ileum. In addition, following the infusion of 9 mmol homoarginine into the vena jugularis less than 0.2% of the infused homoarginine appeared in the intestine.
We concluded from these data that with the homoarginine method endogenous protein in the chyme of the intestine can be distinguished from the food protein as homoarginine is not incorporated into endogenous secreta and free homo arginine is completely absorbed.
Definition
ChEBI: An L-lysine derivative that is the L-enantiomer of homoarginine.
Homoarginine Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16920 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29896 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13193 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34571 | 58 |
View Lastest Price from Homoarginine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-08-16 | Homoarginine
156-86-5
|
US $0.00 / Kg/Drum | 1KG | 98%min | 500kgs | WUHAN FORTUNA CHEMICAL CO., LTD | |
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2021-07-02 | L-homoarginine
156-86-5
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
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2019-07-06 | Homoarginine
156-86-5
|
US $1.00 / KG | 1KG | 99% | 20kg | Career Henan Chemical Co |
-
- Homoarginine
156-86-5
- US $0.00 / Kg/Drum
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- L-homoarginine
156-86-5
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Homoarginine
156-86-5
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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