ChemicalBook >> CAS DataBase List >>(1R,2S,3R)-Aprepitant
(1R,2S,3R)-Aprepitant
- CAS No.
- 1185502-97-9
- Chemical Name:
- (1R,2S,3R)-Aprepitant
- Synonyms
- (R,S,R)-Aprepitant;1R, 2S, 3R)-Aripitan;Aprepitant impurity 06;(2S,3R,1’R)-Aprepitant;Aprepitant (R,S,R)-Isomer;Aprepitant impurity 6/(1R,2S,3R)-Aprepitant;5-([(2S,3R)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one;5-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;3H-1,2,4-Triazol-3-one, 5-[[(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-;3-(((2S,3R)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one (Aprepitant impurity)
- CBNumber:
- CB53146508
- Molecular Formula:
- C23H21F7N4O3
- Molecular Weight:
- 534.43
- MDL Number:
- MFCD24386574
- MOL File:
- 1185502-97-9.mol
Last updated:2024-06-11 18:14:38
(1R,2S,3R)-Aprepitant Chemical Properties,Uses,Production
Uses
(2S,3R,1’R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.
Definition
ChEBI: 5-[[(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-1,2,4-triazol-3-one is a member of morpholines.
(1R,2S,3R)-Aprepitant Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 40)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
CR Corporation Lomited | fred.wen@crcorporation.cn | CHINA | 12069 | 58 | |
Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
ShenZhen H&D Pharmaceutical Technology Co., LTD | +86-0755-22677845 +86-13627253706 | sale@hdimpurity.com | China | 3389 | 58 |
Adamas Reagent, Ltd. | 400-6009262 16621234537 | chenyj@titansci.com | China | 14104 | 59 |
S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-4000505016 13380397412 | 3001272453@qq.com | China | 5056 | 50 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18021 | 56 |
Nanjing XiZe Biotechnology CO., Ltd. | 025-66023220 0086-15250997978 | 1511893459@qq.com | China | 7774 | 55 |
View Lastest Price from (1R,2S,3R)-Aprepitant manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-08-22 | Aprepitant Impurity 23
1185502-97-9
|
US $0.00-0.00 / mg | 10mg | 98% | 500mg | ShenZhen H&D Pharmaceutical Technology Co., LTD |
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- Aprepitant Impurity 23
1185502-97-9
- US $0.00-0.00 / mg
- 98%
- ShenZhen H&D Pharmaceutical Technology Co., LTD
1185502-97-9((1R,2S,3R)-Aprepitant)Related Search:
Aprepitant-M3 Metabolite
1,1,1-Trimethoxy-2-chloroethane
Aprepitant Impurity 19
Benzyl dihydrogen phosphate
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
Aprepitant
Fosaprepitant dimeglumine
5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one
Aprepitant
Aprepitant
1of4
(R,S,R)-Aprepitant
Aprepitant (R,S,R)-Isomer
Aprepitant impurity 6/(1R,2S,3R)-Aprepitant
1R, 2S, 3R)-Aripitan
5-([(2S,3R)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one
3H-1,2,4-Triazol-3-one, 5-[[(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
5-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
(2S,3R,1’R)-Aprepitant
Aprepitant impurity 06
3-(((2S,3R)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one (Aprepitant impurity)
1185502-97-9