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(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole

(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole Structure
(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole structure
CAS No.
681490-91-5
Chemical Name:
(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole
Synonyms
Deflazacort Impurity 14;Delamanid Diol Impurity;(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole;1,2-Propanediol, 3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-, (2R)-
CBNumber:
CB53154143
Molecular Formula:
C7H10ClN3O4
Molecular Weight:
235.62
MDL Number:
MFCD30741734
MOL File:
681490-91-5.mol
Last updated:2023-05-15 10:44:02
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(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole Properties

Boiling point 515.1±60.0 °C(Predicted)
Density 1.61±0.1 g/cm3(Predicted)
solubility soluble in Chloroform, DCM
form Solid
pka 13.48±0.29(Predicted)
color Off-White

(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C367620 (2R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-1,2-propanediol 681490-91-5 25mg $385 2021-12-16 Buy
Medical Isotopes, Inc. 44480 (2R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-1,2-propanediol 681490-91-5 10mg $675 2021-12-16 Buy
Product number Packaging Price Buy
C367620 25mg $385 Buy
44480 10mg $675 Buy

(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole Chemical Properties,Uses,Production

Uses

(2R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-1,2-propanediol is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

DE-7

(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20035 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 18162595016 3287908757@qq.com China 9887 58
Supplier Advantage
Lynnchem 58
Novachemistry 58
Suzhou Meishi Biotechnology Co., Ltd. 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 58
(R)-2-chloro-1-(2,3-dihydroxy-2-methyl)-propyl-4-nitroimidazole 1,2-Propanediol, 3-(2-chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-, (2R)- Delamanid Diol Impurity Deflazacort Impurity 14 681490-91-5