ChemicalBook >> CAS DataBase List >>RSM932A
RSM932A
- CAS No.
- 850807-63-5
- Chemical Name:
- RSM932A
- Synonyms
- TCD717;TCD 717;RSM932A;TCD-717.;RSM-932A; RSM 932A; RSM932A; TCD 717; TCD717; TCD-717.;1,1''-([1,1''-Biphenyl]-4,4''-diylbis(methylene))bis(4-(methyl(p-tolyl)amino)quinolin-1-ium) bromide;1,1'-([1,1'-Biphenyl]-4,4'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)quinolin-1-ium) bromide;1,1'-([1,1'-Biphenyl]-4,4'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)quinolin-1-ium) bromide
- CBNumber:
- CB53168588
- Molecular Formula:
- C46H38BrCl2N4+
- Molecular Weight:
- 797.64
- MDL Number:
- MFCD29058562
- MOL File:
- 850807-63-5.mol
Last updated:2024-07-02 08:55:11
| Melting point | 255-257 °C |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMSO: 3 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml |
| form | A crystalline solid |
| color | White to yellow |
| FDA UNII | KC1UXA6R4Z |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
RSM932A price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2696 | RSM932A ≥97% (HPLC) | 850807-63-5 | 5MG | $97.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2696 | RSM932A ≥97% (HPLC) | 850807-63-5 | 25MG | $395 | 2024-03-01 | Buy |
| Cayman Chemical | 21518 | RSM-932A ≥98% | 850807-63-5 | 1mg | $29 | 2024-03-01 | Buy |
| Cayman Chemical | 21518 | RSM-932A ≥98% | 850807-63-5 | 5mg | $107 | 2024-03-01 | Buy |
| Cayman Chemical | 21518 | RSM-932A ≥98% | 850807-63-5 | 10mg | $197 | 2024-03-01 | Buy |
RSM932A Chemical Properties,Uses,Production
Description
RSM-932A is a selective inhibitor of choline kinase α (CHOKα; IC50s = 1 and >50 μM for CHOKα and β, respectively). It induces apoptosis via CHOP signaling and endoplasmic reticulum (ER) stress in MDA-MB-231, MCF-7, SW620, and H460 cancer cells, but it only induces cell cycle arrest and not apoptosis in NCM460 and MCF-10A normal epithelial cells. RSM-932A inhibits the growth of HT-29 colon cancer cells in vitro (IC50 = 1.15 μM) and in vivo in a mouse xenograft model (ED50 = 7.5 mg/kg).
RSM932A Preparation Products And Raw materials
Raw materials
Preparation Products
RSM932A Suppliers
Global( 25)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 17702719238 | sales@sun-shinechem.com | China | 950 | 64 |
| Zhengzhou Alfachem Co., Ltd. | 0371-53765687 18937137882 | 2853979813@qq.com | China | 7979 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2972 | 58 |
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | 1014988033@qq.com | China | 4977 | 55 |
| Wuhan Sun-shine Bio-technology Corporation Limited | +86-027-6552-2453 | sales@sun-shinechem.com | China | 727 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19105 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | 0519-85788828 13775037613 | sales@chemrenpharm.com | China | 3600 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
RSM932A
RSM-932A; RSM 932A; RSM932A; TCD 717; TCD717; TCD-717.
TCD 717
TCD717
TCD-717.
1,1''-([1,1''-Biphenyl]-4,4''-diylbis(methylene))bis(4-(methyl(p-tolyl)amino)quinolin-1-ium) bromide
1,1'-([1,1'-Biphenyl]-4,4'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)quinolin-1-ium) bromide
1,1'-([1,1'-Biphenyl]-4,4'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)quinolin-1-ium) bromide
850807-63-5
C48H44N42Br