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2-N-HEXYL-4-PENTYNOIC ACID

2-N-HEXYL-4-PENTYNOIC ACID structure

CAS No.: 96017-59-3

Chemical Name:: 2-N-HEXYL-4-PENTYNOIC ACID

Synonyms: Hexyl-4-pentynoic Acid;2-Hexyl-4-pentynoic Acid;2-PROPARGYLOCTANOIC ACID;2-Hexyl-4-pentynoicAcid>2-N-HEXYL-4-PENTYNOIC ACID;2-(2-PROPYNYL)OCTANOIC ACID;Hexyl-4-pentynoic acid (HPA);R-2-(2-propynyl)octanoic acid;2-(2-Propyn-1-yl)octanoic Acid;2-(Prop-2-yn-1-yl)octanoic acid

CBNumber:: CB5317246

Molecular Formula:: C11H18O2

Molecular Weight:: 182.26

MDL Number:: MFCD00946863

MOL File:: 96017-59-3.mol

MSDS File:: SDS

Last updated:2024-11-19 15:53:33

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2-N-HEXYL-4-PENTYNOIC ACID Properties

Boiling point	287.1±23.0 °C(Predicted)
Density	0.94
refractive index	1.4450-1.4510
storage temp.	Inert atmosphere,Room Temperature
solubility	Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form	oil
pka	4.24±0.21(Predicted)
color	Colorless
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Risk Statements

HS Code

2916.19.3000

NFPA 704

	0
2		0

2-N-HEXYL-4-PENTYNOIC ACID price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	H0964	2-Hexyl-4-pentynoic Acid >95.0%(T)	96017-59-3	5g	$239	2024-03-01	Buy
TCI Chemical	H0964	2-Hexyl-4-pentynoic Acid >95.0%(T)	96017-59-3	25g	$762	2024-03-01	Buy
Cayman Chemical	15205	2-hexyl-4-Pentynoic Acid ≥95%	96017-59-3	1g	$120	2024-03-01	Buy
Cayman Chemical	15205	2-hexyl-4-Pentynoic Acid ≥95%	96017-59-3	5g	$257	2024-03-01	Buy
Cayman Chemical	15205	2-hexyl-4-Pentynoic Acid ≥95%	96017-59-3	250mg	$44	2024-03-01	Buy

Product number	Packaging	Price	Buy
H0964	5g	$239	Buy
H0964	25g	$762	Buy
15205	1g	$120	Buy
15205	5g	$257	Buy
15205	250mg	$44	Buy

2-N-HEXYL-4-PENTYNOIC ACID Chemical Properties,Uses,Production

Description

2-hexyl-4-Pentynoic acid is a derivative of valproic acid , an inhibitor of histone deacetylases (HDACs). It inhibits HDAC activity more potently (IC₅₀ = 13 μM) than valproic acid (IC₅₀ = 398 μM). 2-hexyl-4-Pentynoic acid induces histone hyperacetylation in cerebellar granule cells significantly at 5 μM. It also induces the expression of heat shock proteins Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity when used at a concentration of 50 μM.

References

1) Eikel et al. (2006), Teratogenic effects mediated by inhibition of histone deacetylases: evidence from quantitative structure activity relationships of 20 valproic acid derivatives; Chem. Res. Toxicol., 19 272 2) Leng et al. (2010), Potent neuroprotective effects of novel structural derivatives of valproic acid: potential roles of HDAC inhibition and HSP70 induction; Neurosci. Lett., 476 127

2-N-HEXYL-4-PENTYNOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

2-N-HEXYL-4-PENTYNOIC ACID Suppliers

Global( 51)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	021-61259108 18621169109	market03@meryer.com	China	40228	62
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24529	81
Shandong Xiya Chemical Co., Ltd	4009903999 13355009207	3007715519@qq.com	China	18738	57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66099280 17798518460	cfzhang@aikonchem.com	China	19915	55

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
TCI (Shanghai) Development Co., Ltd.	81
Shandong Xiya Chemical Co., Ltd	57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	55

View Lastest Price from 2-N-HEXYL-4-PENTYNOIC ACID manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	2-hexyl-4-Pentynoic Acid 96017-59-3	US $59.00-138.00 / mg			10g	TargetMol Chemicals Inc.

2-hexyl-4-Pentynoic Acid
96017-59-3
US $59.00-138.00 / mg
TargetMol Chemicals Inc.

2-N-HEXYL-4-PENTYNOIC ACID Spectrum

2-N-HEXYL-4-PENTYNOIC ACID(96017-59-3)¹HNMR

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2-N-HEXYL-4-PENTYNOIC ACID

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2-(2-PROPYNYL)OCTANOIC ACID 2-N-HEXYL-4-PENTYNOIC ACID 2-PROPARGYLOCTANOIC ACID 2-Hexyl-4-pentynoic Acid 2-Propargyloctanoic Acid 2-(2-Propynyl)octanoic Acid 2-Hexyl-4-pentynoicAcid> 2-(Prop-2-yn-1-yl)octanoic acid Hexyl-4-pentynoic acid (HPA) R-2-(2-propynyl)octanoic acid Hexyl-4-pentynoic Acid HDAC inhibitor,Heat shock proteins,HSP70,Excitotoxicity,Histone deacetylases,inhibit,HDAC,Neuroprotection,2hexyl4Pentynoic Acid,2 hexyl 4 Pentynoic Acid,Inhibitor,Glutamate,HSP,Valproic acid Octanoic acid, 2-(2-propyn-1-yl)- 2-(2-Propyn-1-yl)octanoic Acid 96017-59-3 Acetylenic Carboxylic Acids & Their Derivatives Acetylenes Acetylenic Carboxylic Acids & Their Derivatives Acetylenes