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2'-Fluoroacetophenone

2'-Fluoroacetophenone structure

CAS No.: 445-27-2

Chemical Name:: 2'-Fluoroacetophenone

Synonyms: 2-FLUOROACETOPHENONE;1-(2-FLUOROPHENYL)ETHANONE;2'-Fluoro;Vonoprazan-041;uoroacetophenone;2-Fluoracetophenon;TAK438 Impurity 97;Fluoroacetophenone1;O-FLUOROACETOPHENONE;2-Acetylfluorobenzene

CBNumber:: CB5330344

Molecular Formula:: C8H7FO

Molecular Weight:: 138.14

MDL Number:: MFCD00000320

MOL File:: 445-27-2.mol

MSDS File:: SDS

Last updated:2025-04-01 17:57:16

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2'-Fluoroacetophenone Properties

Melting point	26-27C
Boiling point	187-189 °C(lit.)
Density	1.137 g/mL at 20 °C(lit.)
refractive index	n20/D 1.507(lit.)
Flash point	143 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Soluble in Acetone, Chloroform, Dichloromethane, Ethanol, Ethyl Acetate and Methanol.
form	Liquid
Specific Gravity	1.121
color	Clear colorless to yellow
BRN	2041344
InChIKey	QMATYTFXDIWACW-UHFFFAOYSA-N
CAS DataBase Reference	445-27-2(CAS DataBase Reference)
NIST Chemistry Reference	o-Fluoroacetophenone(445-27-2)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-37/39-37

RIDADR

1993

WGK Germany

HazardClass

IRRITANT

PackingGroup

III

HS Code

29147090

NFPA 704

	1
2		0

2'-Fluoroacetophenone price More Price(27)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	183717	2′-Fluoroacetophenone 97%	445-27-2	5g	$124	2023-06-20	Buy
TCI Chemical	F0364	2'-Fluoroacetophenone >97.0%(GC)	445-27-2	5g	$16	2024-03-01	Buy
TCI Chemical	F0364	2'-Fluoroacetophenone >97.0%(GC)	445-27-2	25g	$25	2024-03-01	Buy
Alfa Aesar	A15128	2'-Fluoroacetophenone, 97%	445-27-2	5g	$36.65	2024-03-01	Buy
Alfa Aesar	A15128	2'-Fluoroacetophenone, 97%	445-27-2	25g	$115.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
183717	5g	$124	Buy
F0364	5g	$16	Buy
F0364	25g	$25	Buy
A15128	5g	$36.65	Buy
A15128	25g	$115.65	Buy

2'-Fluoroacetophenone Chemical Properties,Uses,Production

Chemical Properties

clear colorless to light yellow or light green

Uses

2'-Fluoroacetophenone is used as starting reagent in the synthesis of ascididemin. It is used to produce 1-(2-piperidin-1-yl-phenyl)-ethanone by reaction with piperidine.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 6179, 1990 DOI: 10.1016/S0040-4039(00)97018-7

General Description

The enantioselective reduction of 2′-fluoroacetophenone has been investigated.

2'-Fluoroacetophenone synthesis

Synthesis of 2'-Fluoroacetophenone from 1-(2-FLUOROPHENYL)-ETHANONE, OXIME

2'-Fluoroacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

5-Fluoro-1-tetralone 5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile ethyl 2-amino-4-(2-fluorophenyl)thiophene-3-carboxylate N-[1-(2-Fluorophenyl)ethylidene]-4-methylbenzenesulfonamide 5-bromo-2-(2-fluorophenyl)-1H-indole

N-Boc-3-Methyl-5-nitroindazole Ethanone, 1-(2-fluorophenyl)-2-(methylthio)- 1-(2-Fluorophenyl)ethanamine hydrochloride 2'-(1-Piperidinyl)acetophenone

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2'-Fluoroacetophenone Suppliers

Global( 581)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shandong Believe Chemical PTE.LTD	+86-18553607090 +8618553607090	1093908296@qq.com	China	1667	58
Nanjing Yushan Wanfang Biotechnology Co., Ltd.	+86-025-84918180 +86-18014482516	3552541679@qq.com	China	997	58
BTC pharm India	+918790379245	banny.janga@btcpharm.com	India	1262	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531157085	abby@chuanghaibio.com	China	8808	58
Hebei Mujin Biotechnology Co.,Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12809	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5868	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18137	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20233	58
Hebei Mujin Biotechnology Co.,Ltd	+8613288715578	angelia@hbmojin.com	China	750	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883 +86-16264648883	niki@zlchemi.com	China	7245	58

Supplier	Advantage
Shandong Believe Chemical PTE.LTD	58
Nanjing Yushan Wanfang Biotechnology Co., Ltd.	58
BTC pharm India	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58

View Lastest Price from 2'-Fluoroacetophenone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-28	2'-Fluoroacetophenone 445-27-2	US $50.00 / kg	1kg	99	5000	Hebei Zhuanglai Chemical Trading Co Ltd
2025-04-27	2'-Fluoroacetophenone 445-27-2	US $300.00 / kg	1kg	98%	100	Hebei Junhua Import and Export Co., LTD
2025-04-23	2'-Fluoroacetophenone 445-27-2	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

2'-Fluoroacetophenone
445-27-2
US $50.00 / kg
99
Hebei Zhuanglai Chemical Trading Co Ltd

2'-Fluoroacetophenone
445-27-2
US $300.00 / kg
98%
Hebei Junhua Import and Export Co., LTD

2'-Fluoroacetophenone
445-27-2
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

2'-Fluoroacetophenone Spectrum

2'-Fluoroacetophenone(445-27-2)MS 2'-Fluoroacetophenone(445-27-2)¹HNMR 2'-Fluoroacetophenone(445-27-2)¹³CNMR 2'-Fluoroacetophenone(445-27-2)IR1 2'-Fluoroacetophenone(445-27-2)Raman

445-27-2(2'-Fluoroacetophenone)Related Search:

L-PICEIN 2-Fluorophenylacetic acid 2',4'-Dichloroacetophenone 2-Fluorobenzyl cyanide 4'-Hydroxyacetophenone

3-Aminoacetophenone Acetophenone 2-Bromoacetophenone 4'-Bromoacetophenone 4'-(Trifluoromethyl)acetophenone

2'-Hydroxyacetophenone 3-Nitroacetophenone 4-Nitroacetophenone 2-BROMO-2'-FLUOROACETOPHENONE ω-Bromo-4-fluoroacetophenone, 4-Fluorophenacyl bromide,2-Bromo-p-fluoroacetophenone,2'-BROMO-4-FLUOROACETOPHENONE,2-BROMO-4'-FLUOROACETOPHENONE

2-Fluoropropiophenone 2'-Bromoacetophenone 5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde

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Fluoroacetophenone1 Fluoroacetophenonemincolorlessliq Ethanone, 1-(2-fluorophenyl)- O-FLUOROACETOPHENONE LABOTEST-BB LT01148268 o-Fluoroacetophenone, min. 97% Adjacent fluorine acetophenone 2'-Flouoroacetophenone 2-Acetylfluorobenzene 2-Fluoroacetophenone,97% 2'-Fluoro 2'-Fluoroacetophenone 97% Vonoprazan Fumarate Impurity 56 Vonoprazan Impurity 31 uoroacetophenone 2-Fluoracetophenon 2'-Fluoroacetophenone> TAK438 Impurity 97 Vonoprazan-041 Vonoprazan Impurity 97 1-(2-Fluorophenyl)ethan-1-one (Vonoprazan Impurity） Methyl 2-fluorophenyl ketone 1-(2-FLUOROPHENYL)ETHANONE 2-FLUOROACETOPHENONE 2'-Fluoroacetophenone 445-27-2 Carbonyl Compounds C7 to C8 Building Blocks Ketones Organic Building Blocks Aromatic Acetophenones & Derivatives (substituted) Fluorobenzene ketone Adehydes, Acetals & Ketones Fluorine Compounds C7 to C8 Acetophenone Series Aryl Fluorinated Building Blocks Building Blocks C7 to C8 C8-C12 Carbonyl Compounds Chemical Synthesis Fluorinated Building Blocks Organic Building Blocks Organic Fluorinated Building Blocks Other Fluorinated Organic Building Blocks Carbonyl Compounds Ketones 11 445-27-2 pharmaceutical