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BocNH-PEG7-OH

CAS No.
1292268-13-3
Chemical Name:
BocNH-PEG7-OH
Synonyms
tert-Butyl (20-hydroxy-3,6,9,12,15,18-hexaoxaicosyl)carbamate;NHBoc-PEG7-OH;BocNH-PEG7-OH;BocNH-PEG7-alcohol;t-Boc-Amido-PEG7-Alcohol;N-Boc-PEG7-alcohol N-Boc-;t-boc-N-amido-PEG7-alcohol;20-(Boc-amino)-3,6,9,12,15,18-hexaoxa-1-icosanol;t-butyl20-hydroxy-3,6,9,12,15,18-hexaoxaicosylcarbamate;5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester
CBNumber:
CB53340579
Molecular Formula:
C19H39NO9
Molecular Weight:
425.51
MDL Number:
MFCD29049415
MOL File:
1292268-13-3.mol
Last updated:2024-10-23 13:36:13

BocNH-PEG7-OH Properties

Boiling point 521.1±50.0 °C(Predicted)
Density 1.090±0.06 g/cm3(Predicted)
solubility Soluble in Water, DMSO, DCM, DMF
pka 12.23±0.46(Predicted)
form Liquid
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

BocNH-PEG7-OH price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm BP-23546 N-Boc-PEG7-alcohol 98% 1292268-13-3 500mg $280 2021-12-16 Buy
Activate Scientific AS104083 BocNH-PEG7-OH 95+% 1292268-13-3 1g $615 2021-12-16 Buy
purepeg 432407 BocNH-PEG7-OH min.95% 1292268-13-3 1g $350 2021-12-16 Buy
purepeg 432407 BocNH-PEG7-OH min.95% 1292268-13-3 250mg $185 2021-12-16 Buy
Acrotein B-0973 BocNH-PEG7-OH 97% 1292268-13-3 0.25g $192.5 2021-12-16 Buy
Product number Packaging Price Buy
BP-23546 500mg $280 Buy
AS104083 1g $615 Buy
432407 1g $350 Buy
432407 250mg $185 Buy
B-0973 0.25g $192.5 Buy

BocNH-PEG7-OH Chemical Properties,Uses,Production

Description

N-Boc-PEG7-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Biological Activity

N-Boc-PEG7-alcohol is a PROTAC bridge that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. Also it is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

PEGs

Alkyl/ether

BocNH-PEG7-OH Preparation Products And Raw materials

Raw materials

Preparation Products

BocNH-PEG7-OH Suppliers

Global( 60)Suppliers
Supplier Tel Email Country ProdList Advantage
9i LLC
+18039569191 MWan@NiNeiLab.com United States 418 58
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 17453 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Wuhan Borenpharm Co., Ltd
027-65563561 18717150066 3207347307@qq.com CHINA 1238 58
Hangzhou Huarong Pharm Co., Ltd.
571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3148 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38632 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2995 58

View Lastest Price from BocNH-PEG7-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Boc-PEG7-alcohol pictures 2024-10-24 N-Boc-PEG7-alcohol
1292268-13-3
US $0.00 / mg 10g TargetMol Chemicals Inc.
NHBoc-PEG7-OH pictures 2024-03-25 NHBoc-PEG7-OH
1292268-13-3
US $0.00 / g 5g >98.00% 5g Xian confluore Biological Technology Co., Ltd.
  • NHBoc-PEG7-OH pictures
  • NHBoc-PEG7-OH
    1292268-13-3
  • US $0.00 / g
  • >98.00%
  • Xian confluore Biological Technology Co., Ltd.
BocNH-PEG7-OH NHBoc-PEG7-OH 5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester t-boc-N-amido-PEG7-alcohol t-butyl20-hydroxy-3,6,9,12,15,18-hexaoxaicosylcarbamate tert-Butyl (20-hydroxy-3,6,9,12,15,18-hexaoxaicosyl)carbamate 20-(Boc-amino)-3,6,9,12,15,18-hexaoxa-1-icosanol BocNH-PEG7-OH/5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester BocNH-PEG7-alcohol N-Boc-PEG7-alcohol N-Boc- tert-butyl N-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate t-Boc-Amido-PEG7-Alcohol 1292268-13-3 C19H39NO9 peg