PF-06726304
- CAS No.
- 1616287-82-1
- Chemical Name:
- PF-06726304
- Synonyms
- PF-6726304;PF-06726304;antitumor,H3K27me3,PF06726304,Karpas-422,EZH2,PF 06726304,Histone Methyltransferase,inhibit,Inhibitor,PF-06726304,Y641N;5,8-dichloro-2-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-7-(3,5-dimethylisoxazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one,;1(2H)-Isoquinolinone, 5,8-dichloro-2-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-7-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-;5,8-dichloro-7-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one
- CBNumber:
- CB53353528
- Molecular Formula:
- C22H21Cl2N3O3
- Molecular Weight:
- 446.33
- MDL Number:
- MFCD31563584
- MOL File:
- 1616287-82-1.mol
Last updated:2023-05-18 11:31:14
PF-06726304 price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PZ0346 | PF-06726304 acetate ≥98% (HPLC) | 1616287-82-1 | 5mg | $114 | 2024-03-01 | Buy |
| Tocris | 6169 | PF-06726304 acetate ≥97%(HPLC) | 1616287-82-1 | 10 | $173 | 2021-12-16 | Buy |
| ChemScene | CS-8072 | PF-06726304 99.64% | 1616287-82-1 | 25mg | $360 | 2021-12-16 | Buy |
| ChemScene | CS-8072 | PF-06726304 99.64% | 1616287-82-1 | 50mg | $660 | 2021-12-16 | Buy |
| ChemScene | CS-8072 | PF-06726304 99.64% | 1616287-82-1 | 10mg | $156 | 2021-12-16 | Buy |
PF-06726304 Chemical Properties,Uses,Production
Biochem/physiol Actions
PF-06726304 is a selective inhibitor of Histone-lysine N-methyltransferase EZH2 (enhancer of Zeste homolog 2), which catalyzes trimethylation of histone H3 lysine 27 (H3K27) and is amplified and/or overexpressed in several human cancers including breast, prostate and lymphoma. PF-06726304 is a novel structural class of EZH2 inhibitor.
PF-06726304 Preparation Products And Raw materials
Raw materials
Preparation Products
PF-06726304 Suppliers
Global( 36)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| NINGBOBENKANGJS PHARMTECHCO., LTD | +8615990591583 15990591583 | CHINA | 2029 | 58 | |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10978 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4692 | 58 |
| Deyang Yuehe Bio-Pharmaceutical Co.,Ltd | 028-82729560 18030702676 | sales@yuehepharm.com | China | 181 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4217 | 55 |
PF-06726304
5,8-dichloro-2-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-7-(3,5-dimethylisoxazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one,
5,8-dichloro-7-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one
PF-6726304
1(2H)-Isoquinolinone, 5,8-dichloro-2-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-7-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-
antitumor,H3K27me3,PF06726304,Karpas-422,EZH2,PF 06726304,Histone Methyltransferase,inhibit,Inhibitor,PF-06726304,Y641N
1616287-82-1