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NGBKFLTYGSREKK-PMACEKPBSA-N
- CAS No.
- 756485-04-8
- Chemical Name:
- NGBKFLTYGSREKK-PMACEKPBSA-N
- Synonyms
- NGBKFLTYGSREKK-PMACEKPBSA-N;Benzyl ((S)-3-methyl-1-oxo-1-(((S)-1-oxo-3-phenylpropan-2-yl)amino)butan-2-yl)carbamate;Carbamic acid, N-[(1S)-1-[[[(1S)-1-formyl-2-phenylethyl]amino]carbonyl]-2-methylpropyl]-, phenylmethyl ester
- CBNumber:
- CB53393010
- Molecular Formula:
- C22H26N2O4
- Molecular Weight:
- 382.45
- MDL Number:
- MOL File:
- 756485-04-8.mol
Last updated:2023-05-04 17:34:42
NGBKFLTYGSREKK-PMACEKPBSA-N Chemical Properties,Uses,Production
Definition
ChEBI: Z-Val-Phe-H is a dipeptide resulting from the formal condensation of the carboxy group of N-benzyloxycarbonyl-L-valine with the amino group of L-phenylalanine aldehyde. It is a potent cell-permeable inhibitor of calpain I and II, and is also a gamma-secretase inhibitor. It has a role as an EC 3.4.22.53 (calpain-2) inhibitor, an EC 3.4.22.52 (calpain-1) inhibitor, an EC 3.4.23.46 (memapsin 2) inhibitor, an antileishmanial agent and an apoptosis inhibitor. It is an aldehyde, a dipeptide and a carbamate ester.
NGBKFLTYGSREKK-PMACEKPBSA-N Preparation Products And Raw materials
Raw materials
Preparation Products
NGBKFLTYGSREKK-PMACEKPBSA-N
Carbamic acid, N-[(1S)-1-[[[(1S)-1-formyl-2-phenylethyl]amino]carbonyl]-2-methylpropyl]-, phenylmethyl ester
Benzyl ((S)-3-methyl-1-oxo-1-(((S)-1-oxo-3-phenylpropan-2-yl)amino)butan-2-yl)carbamate
756485-04-8