ChemicalBook >> CAS DataBase List >>NGBKFLTYGSREKK-PMACEKPBSA-N

NGBKFLTYGSREKK-PMACEKPBSA-N

NGBKFLTYGSREKK-PMACEKPBSA-N structure

CAS No.: 756485-04-8

Chemical Name:: NGBKFLTYGSREKK-PMACEKPBSA-N

Synonyms: NGBKFLTYGSREKK-PMACEKPBSA-N;Benzyl ((S)-3-methyl-1-oxo-1-(((S)-1-oxo-3-phenylpropan-2-yl)amino)butan-2-yl)carbamate;Carbamic acid, N-[(1S)-1-[[[(1S)-1-formyl-2-phenylethyl]amino]carbonyl]-2-methylpropyl]-, phenylmethyl ester

CBNumber:: CB53393010

Molecular Formula:: C22H26N2O4

Molecular Weight:: 382.45

MDL Number:

MOL File:: 756485-04-8.mol

Last updated:2023-05-04 17:34:42

Request For Quotation

NGBKFLTYGSREKK-PMACEKPBSA-N Properties

Boiling point	595.6±50.0 °C(Predicted)
Density	1.153±0.06 g/cm3(Predicted)
pka	11.05±0.46(Predicted)

NGBKFLTYGSREKK-PMACEKPBSA-N Chemical Properties,Uses,Production

Definition

ChEBI: Z-Val-Phe-H is a dipeptide resulting from the formal condensation of the carboxy group of N-benzyloxycarbonyl-L-valine with the amino group of L-phenylalanine aldehyde. It is a potent cell-permeable inhibitor of calpain I and II, and is also a gamma-secretase inhibitor. It has a role as an EC 3.4.22.53 (calpain-2) inhibitor, an EC 3.4.22.52 (calpain-1) inhibitor, an EC 3.4.23.46 (memapsin 2) inhibitor, an antileishmanial agent and an apoptosis inhibitor. It is an aldehyde, a dipeptide and a carbamate ester.

NGBKFLTYGSREKK-PMACEKPBSA-N Preparation Products And Raw materials

Raw materials

Preparation Products

NGBKFLTYGSREKK-PMACEKPBSA-N Carbamic acid, N-[(1S)-1-[[[(1S)-1-formyl-2-phenylethyl]amino]carbonyl]-2-methylpropyl]-, phenylmethyl ester Benzyl ((S)-3-methyl-1-oxo-1-(((S)-1-oxo-3-phenylpropan-2-yl)amino)butan-2-yl)carbamate 756485-04-8